2-Pyrrolidinepropanoic acid, 1-[(1,1-dimethylethoxy)carbonyl]-β-methoxy-α-methyl-, (αR,βR,2S)-, compd. with N-cyclohexylcyclohexanamine (1:1)

Product Name: 2-Pyrrolidinepropanoic acid, 1-[(1,1-dimethylethoxy)carbonyl]-β-methoxy-α-methyl-, (αR,βR,2S)-, compd. with N-cyclohexylcyclohexanamine (1:1)
CAS No.: 1369427-40-6
Chemical Name: 2-Pyrrolidinepropanoic acid, 1-[(1,1-dimethylethoxy)carbonyl]-β-methoxy-α-methyl-, (αR,βR,2S)-, compd. with N-cyclohexylcyclohexanamine (1:1)
Synonyms: Boc-Dap-OH.DCHA;N-Boc-Dolaproline DCHA;N-Boc-dolaproine (dicyclohexylamine);N-Boc-(2R,3R,4S)-dolaproine DCHA salt;(2R,3R)-BOC-dolaproine dicyclohexylamine;Dicyclohexylamine (2R,3R)-3-[(S)-1-Boc-2-pyrrolidinyl]-3-methoxy-2-methylpropanoate;(2R,3R)-3-((S)-1-(tert-butoxycarbonyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanoic acid.DHEA;dicyclohexylamine (2R,3R)-3-((S)-1-(tert-butoxycarbonyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanoate;(2R,3R)-3-((S)-1-(tert-butoxycarbonyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanoic acid N-cyclohexylcyclohexanamine salt;(2R,3R)-3-((S)-1-(tert-butoxycarbonyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanoic acid N-cyclohexylcyclohexanamine salt(1:1)
CBNumber: CB63367339
Molecular Formula: C26H48N2O5
Formula Weight: 468.68
MOL File: 1369427-40-6.mol

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2-Pyrrolidinepropanoic acid, 1-[(1,1-dimethylethoxy)carbonyl]-β-methoxy-α-methyl-, (αR,βR,2S)-, compd. with N-cyclohexylcyclohexanamine (1:1) Property

storage temp.: 2-8°C, stored under nitrogen, away from moisture
form: Solid
color: White to off-white
InChIKey: PKZALTWOMMNNOL-QNEVMNBPNA-N
SMILES: N(C1CCCCC1)C1CCCCC1.[C@@H]([C@]1([H])CCCN1C(=O)OC(C)(C)C)(OC)[C@@H](C)C(=O)O |&1:13,14,29,r|

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Hazard and Precautionary Statements (GHS)

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2-Pyrrolidinepropanoic acid, 1-[(1,1-dimethylethoxy)carbonyl]-β-methoxy-α-methyl-, (αR,βR,2S)-, compd. with N-cyclohexylcyclohexanamine (1:1) Chemical Properties,Usage,Production

Uses

N-Boc-dolaproine dicyclohexylamine is an amino acid residue of the pentapeptide Dolastatin 10 (HY-15580). Dolastatin 10 inhibits tubulin polymerization and mitosis and has anticancer activity. And contains dicyclohexylamine[1].

References

[1] Almeida W P, et al. An easy and stereoselective synthesis of N-Boc-dolaproine via the Baylis–Hillman reaction[J]. Tetrahedron letters, 2003, 44(5): 937-940.

2-Pyrrolidinepropanoic acid, 1-[(1,1-dimethylethoxy)carbonyl]-β-methoxy-α-methyl-, (αR,βR,2S)-, compd. with N-cyclohexylcyclohexanamine (1:1) Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Pyrrolidinepropanoic acid, 1-[(1,1-dimethylethoxy)carbonyl]-β-methoxy-α-methyl-, (αR,βR,2S)-, compd. with N-cyclohexylcyclohexanamine (1:1) Suppliers

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1369427-40-6, 2-Pyrrolidinepropanoic acid, 1-[(1,1-dimethylethoxy)carbonyl]-β-methoxy-α-methyl-, (αR,βR,2S)-, compd. with N-cyclohexylcyclohexanamine (1:1)Related Search:

2-Pyrrolidinepropanoic acid, 1-[(1,1-dimethylethoxy)carbonyl]-β-methoxy-α-methyl-, (αR,βR,2S)-, compd. with N-cyclohexylcyclohexanamine (1:1)

(2R,3R)-3-((S)-1-(tert-butoxycarbonyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanoic acid.DHEA

dicyclohexylamine (2R,3R)-3-((S)-1-(tert-butoxycarbonyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanoate

(2R,3R)-3-((S)-1-(tert-butoxycarbonyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanoic acid N-cyclohexylcyclohexanamine salt

2-Pyrrolidinepropanoic acid, 1-[(1,1-dimethylethoxy)carbonyl]-β-methoxy-α-methyl-, (αR,βR,2S)-, compd. with N-cyclohexylcyclohexanamine

2-Pyrrolidinepropanoic acid, 1-[(1,1-dimethylethoxy)carbonyl]-b-methoxy-a-methyl-, (aR,bR,2S)-, compd. with N-cyclohexylcyclohexanamine

(2R,3R)-3-((S)-1-(tert-butoxycarbonyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanoic acid N-cyclohexylcyclohexanamine salt(1:1)

2-?Pyrrolidinepropanoic acid, 1-?[(1,?1-?dimethylethoxy)?carbonyl]?-?β-?methoxy-?α-?methyl-?, (αR,?βR,?2S)?-?, compd. with N-?cyclohexylcyclohexan?amine

N-cyclohexylcyclohexanamine (2R,3R)-3-methoxy-2-methyl-3-[(2S)-1-[(2-methylpropan-2-YL)oxycarbonyl]pyrrolidin-2-YL]propanoic acid

2-PYRROLIDINEPROPANOIC ACID, 1-[(1,1-DIMETHYLETHOXY)CARBONYL]-BETA-METHOXY-ALPHA-METHYL-, (ALPHAR,BETAR,2S)-, COMPD WITH N-CYCLOHEXYLCYCLOHEXANAMINE (1:1)

N-Boc-(2R,3R,4S)-dolaproine DCHA salt

Boc-Dap-OH.DCHA

N-Boc-dolaproine (dicyclohexylamine)

N-Boc-Dolaproline DCHA

Dicyclohexylamine (2R,3R)-3-[(S)-1-Boc-2-pyrrolidinyl]-3-methoxy-2-methylpropanoate

2-Pyrrolidinepropanoic acid, 1-[(1,1-dimethylethoxy)carbonyl]-β-methoxy-α-methyl-, (αR,βR,2S)-, compd. with N-cyclohexylcyclohexanamine (1:1)

(2R,3R)-BOC-dolaproine dicyclohexylamine

1369427-40-6

C12H23NC14H25NO5

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