ChemicalBook > CAS DataBase List > 2-Pyrrolidinepropanoic acid, 1-[(1,1-dimethylethoxy)carbonyl]-β-methoxy-α-methyl-, (αR,βR,2S)-, compd. with N-cyclohexylcyclohexanamine (1:1)

2-Pyrrolidinepropanoic acid, 1-[(1,1-dimethylethoxy)carbonyl]-β-methoxy-α-methyl-, (αR,βR,2S)-, compd. with N-cyclohexylcyclohexanamine (1:1)

Product Name
2-Pyrrolidinepropanoic acid, 1-[(1,1-dimethylethoxy)carbonyl]-β-methoxy-α-methyl-, (αR,βR,2S)-, compd. with N-cyclohexylcyclohexanamine (1:1)
CAS No.
1369427-40-6
Chemical Name
2-Pyrrolidinepropanoic acid, 1-[(1,1-dimethylethoxy)carbonyl]-β-methoxy-α-methyl-, (αR,βR,2S)-, compd. with N-cyclohexylcyclohexanamine (1:1)
Synonyms
Boc-Dap-OH.DCHA;N-Boc-Dolaproline DCHA;N-Boc-dolaproine (dicyclohexylamine);N-Boc-(2R,3R,4S)-dolaproine DCHA salt;(2R,3R)-BOC-dolaproine dicyclohexylamine;Dicyclohexylamine (2R,3R)-3-[(S)-1-Boc-2-pyrrolidinyl]-3-methoxy-2-methylpropanoate;(2R,3R)-3-((S)-1-(tert-butoxycarbonyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanoic acid.DHEA;dicyclohexylamine (2R,3R)-3-((S)-1-(tert-butoxycarbonyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanoate;(2R,3R)-3-((S)-1-(tert-butoxycarbonyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanoic acid N-cyclohexylcyclohexanamine salt;(2R,3R)-3-((S)-1-(tert-butoxycarbonyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanoic acid N-cyclohexylcyclohexanamine salt(1:1)
CBNumber
CB63367339
Molecular Formula
C26H48N2O5
Formula Weight
468.68
MOL File
1369427-40-6.mol
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2-Pyrrolidinepropanoic acid, 1-[(1,1-dimethylethoxy)carbonyl]-β-methoxy-α-methyl-, (αR,βR,2S)-, compd. with N-cyclohexylcyclohexanamine (1:1) Property

storage temp. 
2-8°C, stored under nitrogen, away from moisture
form 
Solid
color 
White to off-white
InChIKey
PKZALTWOMMNNOL-QNEVMNBPNA-N
SMILES
N(C1CCCCC1)C1CCCCC1.[C@@H]([C@]1([H])CCCN1C(=O)OC(C)(C)C)(OC)[C@@H](C)C(=O)O |&1:13,14,29,r|
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Hazard and Precautionary Statements (GHS)

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2-Pyrrolidinepropanoic acid, 1-[(1,1-dimethylethoxy)carbonyl]-β-methoxy-α-methyl-, (αR,βR,2S)-, compd. with N-cyclohexylcyclohexanamine (1:1) Chemical Properties,Usage,Production

Uses

N-Boc-dolaproine dicyclohexylamine is an amino acid residue of the pentapeptide Dolastatin 10 (HY-15580). Dolastatin 10 inhibits tubulin polymerization and mitosis and has anticancer activity. And contains dicyclohexylamine[1].

References

[1] Almeida W P, et al. An easy and stereoselective synthesis of N-Boc-dolaproine via the Baylis–Hillman reaction[J]. Tetrahedron letters, 2003, 44(5): 937-940.

2-Pyrrolidinepropanoic acid, 1-[(1,1-dimethylethoxy)carbonyl]-β-methoxy-α-methyl-, (αR,βR,2S)-, compd. with N-cyclohexylcyclohexanamine (1:1) Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Pyrrolidinepropanoic acid, 1-[(1,1-dimethylethoxy)carbonyl]-β-methoxy-α-methyl-, (αR,βR,2S)-, compd. with N-cyclohexylcyclohexanamine (1:1) Suppliers

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1369427-40-6, 2-Pyrrolidinepropanoic acid, 1-[(1,1-dimethylethoxy)carbonyl]-β-methoxy-α-methyl-, (αR,βR,2S)-, compd. with N-cyclohexylcyclohexanamine (1:1)Related Search:


  • 2-Pyrrolidinepropanoic acid, 1-[(1,1-dimethylethoxy)carbonyl]-β-methoxy-α-methyl-, (αR,βR,2S)-, compd. with N-cyclohexylcyclohexanamine (1:1)
  • (2R,3R)-3-((S)-1-(tert-butoxycarbonyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanoic acid.DHEA
  • dicyclohexylamine (2R,3R)-3-((S)-1-(tert-butoxycarbonyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanoate
  • (2R,3R)-3-((S)-1-(tert-butoxycarbonyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanoic acid N-cyclohexylcyclohexanamine salt
  • 2-Pyrrolidinepropanoic acid, 1-[(1,1-dimethylethoxy)carbonyl]-β-methoxy-α-methyl-, (αR,βR,2S)-, compd. with N-cyclohexylcyclohexanamine
  • 2-Pyrrolidinepropanoic acid, 1-[(1,1-dimethylethoxy)carbonyl]-b-methoxy-a-methyl-, (aR,bR,2S)-, compd. with N-cyclohexylcyclohexanamine
  • (2R,3R)-3-((S)-1-(tert-butoxycarbonyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanoic acid N-cyclohexylcyclohexanamine salt(1:1)
  • 2-?Pyrrolidinepropanoic acid, 1-?[(1,?1-?dimethylethoxy)?carbonyl]?-?β-?methoxy-?α-?methyl-?, (αR,?βR,?2S)?-?, compd. with N-?cyclohexylcyclohexan?amine
  • N-cyclohexylcyclohexanamine (2R,3R)-3-methoxy-2-methyl-3-[(2S)-1-[(2-methylpropan-2-YL)oxycarbonyl]pyrrolidin-2-YL]propanoic acid
  • 2-PYRROLIDINEPROPANOIC ACID, 1-[(1,1-DIMETHYLETHOXY)CARBONYL]-BETA-METHOXY-ALPHA-METHYL-, (ALPHAR,BETAR,2S)-, COMPD WITH N-CYCLOHEXYLCYCLOHEXANAMINE (1:1)
  • N-Boc-(2R,3R,4S)-dolaproine DCHA salt
  • Boc-Dap-OH.DCHA
  • N-Boc-dolaproine (dicyclohexylamine)
  • N-Boc-Dolaproline DCHA
  • Dicyclohexylamine (2R,3R)-3-[(S)-1-Boc-2-pyrrolidinyl]-3-methoxy-2-methylpropanoate
  • 2-Pyrrolidinepropanoic acid, 1-[(1,1-dimethylethoxy)carbonyl]-β-methoxy-α-methyl-, (αR,βR,2S)-, compd. with N-cyclohexylcyclohexanamine (1:1)
  • (2R,3R)-BOC-dolaproine dicyclohexylamine
  • 1369427-40-6
  • C12H23NC14H25NO5
  • ADC
  • ADCs