Bromo-PEG3-CH2CO2tBu

Product Name: Bromo-PEG3-CH2CO2tBu
CAS No.: 2100306-71-4
Chemical Name: Bromo-PEG3-CH2CO2tBu
Synonyms: tert-butyl 2-(2-(2-(2-bromoethoxy)ethoxy)ethoxy)acetate;Br-PEG3-CH2-Boc;Br-PEG3-CH2COOtBu;Bromo-PEG3-CH2-Boc;Bromo-PEG3-CH2CO2tBu;CH2COOH t-Bu Ester-PEG3-Bromide;t-butyl acetate-PEG3-bromide BROMO-PEG3-CH2CO2TBU;Acetic acid, 2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester;Br-PEG3-CH2COOtBu/Acetic acid, 2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester
CBNumber: CB63373596
Molecular Formula: C12H23BrO5
Formula Weight: 327.21
MOL File: 2100306-71-4.mol

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Bromo-PEG3-CH2CO2tBu Property

Boiling point:: 360.9±27.0 °C(Predicted)
Density: 1.246±0.06 g/cm3(Predicted)
storage temp.: Storage temp. 2-8°C
solubility: Soluble in DMSO, DCM, DMF
form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Activate Scientific

Product number: AS104005
Product name: Br-PEG3-CH2COOtBu
Purity: 95+%
Packaging: 250mg
Price: $350
Updated: 2021/12/16

BroadPharm

Product number: BP-23572
Product name: Bromo-PEG3-CH2CO2tBu
Purity: 98%
Packaging: 250mg
Price: $650
Updated: 2021/12/16

Activate Scientific

Product number: AS104005
Product name: Br-PEG3-CH2COOtBu
Purity: 95+%
Packaging: 1g
Price: $745
Updated: 2021/12/16

Activate Scientific

Product number: AS104005
Product name: Br-PEG3-CH2COOtBu
Purity: 95+%
Packaging: 5G
Price: $1613
Updated: 2021/12/16

Acrotein

Product number: B-0863
Product name: Br-PEG3-CH2COOtBu
Purity: 97%
Packaging: 0.25g
Price: $201.66
Updated: 2021/12/16

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Bromo-PEG3-CH2CO2tBu Chemical Properties,Usage,Production

Description

Bromo-PEG3-CH2CO2tBu is a PEG linker containing a bromide group and a t-butyl protected carboxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Uses

Bromo-PEG3-CH2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Bromo-PEG3-CH2CO2tBu Preparation Products And Raw materials

Raw materials

Preparation Products

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Bromo-PEG3-CH2CO2tBu Suppliers

China 43 United States 4 Global 47

T&W GROUP

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2100306-71-4, Bromo-PEG3-CH2CO2tBuRelated Search:

Bromo-PEG3-CH2CO2tBu

Br-PEG3-CH2COOtBu

Bromo-PEG3-CH2-Boc

t-butyl acetate-PEG3-bromide BROMO-PEG3-CH2CO2TBU

Acetic acid, 2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester

tert-butyl 2-(2-(2-(2-bromoethoxy)ethoxy)ethoxy)acetate

Br-PEG3-CH2COOtBu/Acetic acid, 2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester

Br-PEG3-CH2-Boc

CH2COOH t-Bu Ester-PEG3-Bromide

2100306-71-4