4-ACETAMIDOBENZYL ALCOHOL
- Product Name
- 4-ACETAMIDOBENZYL ALCOHOL
- CAS No.
- 16375-88-5
- Chemical Name
- 4-ACETAMIDOBENZYL ALCOHOL
- Synonyms
- N-(4-(Hydroxymethyl);4-ACETAMIDOBENZYL ALCOHOL;4-acetaminobenzyl alcohol;Chloramphenicol Impurity 17;4-Acetamidobenzylalcohol,97%;4-(Acetylamino)benzyl alcohol;N-[4-(HYDROXYMETHYL)PHENYL]ACETAMIDE;Acetamide, N-[4-(hydroxymethyl)phenyl]-
- CBNumber
- CB6358510
- Molecular Formula
- C9H11NO2
- Formula Weight
- 165.19
- MOL File
- 16375-88-5.mol
4-ACETAMIDOBENZYL ALCOHOL Property
- Melting point:
- 120-122°C
- Boiling point:
- 120-122
- Density
- 1.211±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 14.37±0.10(Predicted)
- color
- Off-White
- λmax
- 246nm(MeOH)(lit.)
- InChI
- InChI=1S/C9H11NO2/c1-7(12)10-9-4-2-8(6-11)3-5-9/h2-5,11H,6H2,1H3,(H,10,12)
- InChIKey
- XEYORFKUJZEQCH-UHFFFAOYSA-N
- SMILES
- C(NC1=CC=C(CO)C=C1)(=O)C
- CAS DataBase Reference
- 16375-88-5(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36/37/39
- HS Code
- 2906290090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- H1605
- Product name
- N-[4-(Hydroxymethyl)phenyl]acetamide
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $49
- Updated
- 2025/07/31
- Product number
- H1605
- Product name
- N-[4-(Hydroxymethyl)phenyl]acetamide
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $144
- Updated
- 2025/07/31
- Product number
- B400633
- Product name
- 4-AcetamidobenzylAlcohol
- Packaging
- 500mg
- Price
- $70
- Updated
- 2021/12/16
- Product number
- 003148
- Product name
- 4-Acetamidobenzyl alcohol
- Packaging
- 1g
- Price
- $45
- Updated
- 2021/12/16
- Product number
- FA70499
- Product name
- 4-Acetamidobenzyl alcohol
- Packaging
- 25g
- Price
- $75
- Updated
- 2021/12/16
4-ACETAMIDOBENZYL ALCOHOL Chemical Properties,Usage,Production
Chemical Properties
White to off-white powder
Uses
4-Acetamidobenzyl Alcohol is a useful research chemical, a metabolites of a blocked chloramphenicol producer. It can be used to regulate plant growth.
Synthesis
122-85-0
16375-88-5
4-Acetamidobenzaldehyde (10 g, 61.3 mmol) was dissolved in methanol (100 mL) at room temperature, followed by batchwise addition of sodium borohydride (800 mg). The reaction mixture was stirred overnight at room temperature and the reaction progress was monitored by thin layer chromatography (TLC) using 4:1 hexane:ethyl acetate as eluent. Completion of the reduction reaction was indicated when TLC showed complete disappearance of the feedstock. Subsequently, the reaction mixture was concentrated using a rotary evaporator. The concentrated residue was partitioned between water (25 mL) and ethyl acetate (4 x 50 mL), and the organic layer was separated and washed with brine (25 mL). The organic layer was dried over anhydrous sodium sulfate and the solvent was removed under reduced pressure to give the light yellow solid product N-[4-(hydroxymethyl)phenyl]acetamide. The product was dried under high vacuum to give a final 8.6 g (85% yield). The structure of the product was confirmed by 1H NMR (DMSO-d6): δ 2.0 (s, 3H), 4.5 (d, 2H), 5.2 (t, 1H), 7.25 (d, 2H), 7.55 (d, 2H), 9.95 (s, 1H).
References
[1] Advanced Synthesis and Catalysis, 2018, vol. 360, # 4, p. 676 - 681
[2] Chemical Communications, 2015, vol. 51, # 46, p. 9567 - 9570
[3] Organic Letters, 2017, vol. 19, # 13, p. 3656 - 3659
[4] Catalysis Science and Technology, 2013, vol. 3, # 1, p. 81 - 84
[5] Patent: US2007/149462, 2007, A1. Location in patent: Page/Page column 22
4-ACETAMIDOBENZYL ALCOHOL Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-ACETAMIDOBENZYL ALCOHOL manufacturers
- Product
- 4-ACETAMIDOBENZYL ALCOHOL 16375-88-5
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2019-12-30