ChemicalBook > CAS DataBase List > 2-hydroxy-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide

2-hydroxy-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide

Product Name
2-hydroxy-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide
CAS No.
1099592-35-4
Chemical Name
2-hydroxy-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide
Synonyms
NASH;NSAH, 10 mM in DMSO;Naphthyl salicylic acyl hydrazone;(E)-2-Hydroxy-N'-((2-hydroxynaphthalen-1-yl)methylene)benzohydrazide;(E)-2-Hydroxy-N'-((2-hydroxynaphthalen-1-yl)methylene)benzohydrazide;DNA/RNA Synthesis,HCT116,MDA-231,Panc1,Inhibitor,NSAH,inhibit,S-phase;2-hydroxy-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide;2-hydroxy-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide;Benzoic acid, 2-hydroxy-, (2E)-2-[(2-hydroxy-1-naphthalenyl)methylene]hydrazide
CBNumber
CB63715947
Molecular Formula
C18H14N2O3
Formula Weight
306.32
MOL File
1099592-35-4.mol
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2-hydroxy-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide Property

storage temp. 
Store at -20°C
solubility 
DMSO : 62.5 mg/mL (204.03 mM; Need ultrasonic)
form 
Solid
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0063330
Product name
NSAH
Purity
98.62%
Packaging
5mg
Price
$80
Updated
2021/12/16
ChemScene
Product number
CS-0063330
Product name
NSAH
Purity
98.62%
Packaging
10mg
Price
$140
Updated
2021/12/16
ChemScene
Product number
CS-0063330
Product name
NSAH
Purity
98.62%
Packaging
25mg
Price
$280
Updated
2021/12/16
ChemScene
Product number
CS-0063330
Product name
NSAH
Purity
98.62%
Packaging
50mg
Price
$450
Updated
2021/12/16
ChemScene
Product number
CS-0063330
Product name
NSAH
Purity
98.62%
Packaging
100mg
Price
$720
Updated
2021/12/16
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2-hydroxy-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide Chemical Properties,Usage,Production

Biological Activity

NSAH is a cell penetrant, potent and selective nonnucleoside reversible inhibitor of large subunit (hRRM1) of hRR (human ribonucleotide reductase). NSAH binds to catalytic site of hRRM1. It inhibits hRR in cells. NSAH exhibit potent cytotoxicity toward cancer cells, while demonstrated very moderate toxicity against normal blood progenitor cells.

2-hydroxy-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide Preparation Products And Raw materials

Raw materials

Preparation Products

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2-hydroxy-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide Suppliers

China 25 Russia 1 United States 4 Global 30
Shandong Jirun Biomedical Technology Co., Ltd.
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0539-0539-8613587 17661611089
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qq2639273505
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China
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Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696，15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4573
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Tianjin Kailiqi Biotechnology Co., Ltd.
Tel
15076683720
Fax
022-23754520
Email
klq@cw-bio.com
Country
China
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ShangHai Biochempartner Co.,Ltd
Tel
17754423994 17754423994
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QQ:2853530913
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China
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Shandong Chenxi Pharmaceutical Co., Ltd.
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sales@chemedpharma.com
Country
China
ProdList
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TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
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marketing@targetmol.com
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United States
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32161
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InvivoChem
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Wuxi Donghe Pharmaceutical Technology Co., Ltd.
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63313187 15358055255
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Jinan Jiuli Biotechnology Co. , Ltd.
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Bide Pharmatech Ltd.
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product02@bidepharm.com
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China
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1099592-35-4, 2-hydroxy-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazideRelated Search:


  • 2-hydroxy-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide
  • Naphthyl salicylic acyl hydrazone
  • Benzoic acid, 2-hydroxy-, (2E)-2-[(2-hydroxy-1-naphthalenyl)methylene]hydrazide
  • (E)-2-Hydroxy-N'-((2-hydroxynaphthalen-1-yl)methylene)benzohydrazide
  • NASH
  • DNA/RNA Synthesis,HCT116,MDA-231,Panc1,Inhibitor,NSAH,inhibit,S-phase
  • (E)-2-Hydroxy-N'-((2-hydroxynaphthalen-1-yl)methylene)benzohydrazide
  • 2-hydroxy-N'-[(E)-(2-hydroxynaphthalen-1-yl)methylidene]benzohydrazide
  • NSAH, 10 mM in DMSO
  • 1099592-35-4