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(-)-BICUCULLINE METHOCHLORIDE

Product Name
(-)-BICUCULLINE METHOCHLORIDE
CAS No.
53552-05-9
Chemical Name
(-)-BICUCULLINE METHOCHLORIDE
Synonyms
l-Bicuculline methochloride;(-)-BICUCULLINE METHOCHLORIDE;(?)-Bicuculline methochloride;(-)-Bicuculline methylchloride;( ) Bicuculline methochloride,()Bicuculline methochloride;[R-(R,S)]-5-(6,8-Dihydro-8-oxofuro[3,4-e]-1,3-benzodioxol-6-yl)-5,6,7,8-tetrahydro-6,6-dimethyl-1,3-dioxolo[4,5-g]isoquinolinium chloride;[R-(R*,S*)]-5-(6,8-DIHYDRO-8-OXOFURO[3,4-E]-1,3-BENZODIOXOL-6-YL)-5,6,7,8-TETRAHYDRO-6,6-DIMETHYL-1,3-DIOXOLO[4,5-G]ISOQUINOLINIUM CHLORIDE;1,3-Dioxolo[4,5-g]isoquinolinium,5-[(6S)-6,8-dihydro-8-oxofuro[3,4-e]-1,3-benzodioxol-6-yl]-5,6,7,8-tetrahydro-6,6-dimethyl-,chloride (1:1), (5R)-
CBNumber
CB6373056
Molecular Formula
C21H20ClNO6
Formula Weight
417.84
MOL File
53552-05-9.mol
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(-)-BICUCULLINE METHOCHLORIDE Property

storage temp. 
Store at RT
solubility 
DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 10 mg/ml
form 
Powder
Water Solubility 
Soluble to 100 mM in water
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H300Fatal if swallowed

H311Toxic in contact with skin

H331Toxic if inhaled

H400Very toxic to aquatic life

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P311Call a POISON CENTER or doctor/physician.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P322Specific measures (see …on this label).

P330Rinse mouth.

P361Remove/Take off immediately all contaminated clothing.

P363Wash contaminated clothing before reuse.

P391Collect spillage. Hazardous to the aquatic environment

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
27802
Product name
(−)-Bicuculline methochloride
Packaging
10mg
Price
$115
Updated
2024/03/01
Cayman Chemical
Product number
27802
Product name
(−)-Bicuculline methochloride
Packaging
50mg
Price
$410
Updated
2024/03/01
Cayman Chemical
Product number
27802
Product name
(−)-Bicuculline methochloride
Packaging
5mg
Price
$64
Updated
2024/03/01
Cayman Chemical
Product number
27802
Product name
(−)-Bicuculline methochloride
Packaging
25mg
Price
$252
Updated
2024/03/01
TRC
Product number
B382510
Product name
(-)-BicucullineMethochloride
Packaging
5mg
Price
$225
Updated
2021/12/16
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(-)-BICUCULLINE METHOCHLORIDE Chemical Properties,Usage,Production

Uses

(-)-Bicuculline Methochloride is a GABA receptor inhibitor. Convulsant.

Biological Activity

Methochloride salt of (+)-bicuculline ([R-(R*,S*)]-6-(5,6,7,8-Tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)furo[3,4-e]-1,3-benzodioxol-8(6H)-one ). Water soluble and more stable than bicuculline. Non-GABA receptor-mediated actions reported.

target

GABA Receptor

(-)-BICUCULLINE METHOCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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53552-05-9, (-)-BICUCULLINE METHOCHLORIDERelated Search:


  • [R-(R*,S*)]-5-(6,8-DIHYDRO-8-OXOFURO[3,4-E]-1,3-BENZODIOXOL-6-YL)-5,6,7,8-TETRAHYDRO-6,6-DIMETHYL-1,3-DIOXOLO[4,5-G]ISOQUINOLINIUM CHLORIDE
  • (-)-BICUCULLINE METHOCHLORIDE
  • [R-(R,S)]-5-(6,8-Dihydro-8-oxofuro[3,4-e]-1,3-benzodioxol-6-yl)-5,6,7,8-tetrahydro-6,6-dimethyl-1,3-dioxolo[4,5-g]isoquinolinium chloride
  • l-Bicuculline methochloride
  • 1,3-Dioxolo[4,5-g]isoquinolinium,5-[(6S)-6,8-dihydro-8-oxofuro[3,4-e]-1,3-benzodioxol-6-yl]-5,6,7,8-tetrahydro-6,6-dimethyl-,chloride (1:1), (5R)-
  • (?)-Bicuculline methochloride
  • ( ) Bicuculline methochloride,()Bicuculline methochloride
  • (-)-Bicuculline methylchloride
  • 53552-05-9
  • C21H20NO6Cl
  • GABA/Glycine receptor
  • GABA