ETHYL ADENINE-9-ACETATE
- Product Name
- ETHYL ADENINE-9-ACETATE
- CAS No.
- 25477-96-7
- Chemical Name
- ETHYL ADENINE-9-ACETATE
- Synonyms
- ETHYL ADENINE-9-ACETATE;ETHYL ADENINE-9-ACETATE 97%;Adenine acetic acid ethyl ester;ethyl 2-(9H-adenin-9-yl)acetate;Ethyl2-(6-amino-9H-purin-9-yl)acetate;6-Amino-9H-purine-9-acetic acid ethyl ester;9H-Purine-9-acetic acid, 6-amino-, ethyl ester;(6-Amino-9H-purine-9-yl)acetic acid ethyl ester;2-(6-Amino-9H-purin-9-yl)acetic acid ethyl ester
- CBNumber
- CB6375621
- Molecular Formula
- C9H11N5O2
- Formula Weight
- 221.22
- MOL File
- 25477-96-7.mol
ETHYL ADENINE-9-ACETATE Property
- Melting point:
- 224-228 °C (dec.)(lit.)
- Boiling point:
- 443.1±55.0 °C(Predicted)
- Density
- 1.52±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- pka
- 3.78±0.10(Predicted)
- Appearance
- Off-white to pink Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B433858
- Product name
- EthylAdenine-9-acetate
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- CS-0037933
- Product name
- Ethyl2-(6-amino-9H-purin-9-yl)acetate
- Packaging
- 1g
- Price
- $71
- Updated
- 2021/12/16
- Product number
- CS-0037933
- Product name
- Ethyl2-(6-amino-9H-purin-9-yl)acetate
- Packaging
- 5g
- Price
- $291
- Updated
- 2021/12/16
- Product number
- J50080
- Product name
- Ethyladenine-9-acetate
- Packaging
- 10g
- Price
- $312
- Updated
- 2021/12/16
- Product number
- A174863
- Product name
- Ethyladenine-9-acetate
- Purity
- 95%
- Packaging
- 250mg
- Price
- $25
- Updated
- 2021/12/16
ETHYL ADENINE-9-ACETATE Chemical Properties,Usage,Production
Synthesis
105-36-2
66224-66-6
25477-96-7
Example 26 Synthesis of ethyl 9-carboxymethyladenine: Adenine (10 g, 74 mmol) and potassium carbonate (10.29 g, 74 mmol) were suspended in N,N-dimethylformamide (DMF) followed by the addition of ethyl bromoacetate (8.24 mL, 74 mmol). The reaction mixture was stirred at room temperature and under nitrogen protection for 2.5 h. After completion of the reaction, it was filtered. The solid residue was washed three times with DMF (10 mL). All filtrates were combined and the solvent was removed by distillation under reduced pressure to give a yellow-orange solid. To this solid, water (200 mL) was added and the pH was adjusted to 6 with 4 N hydrochloric acid. after stirring for 10 min at 0 °C, the precipitate was collected, washed with water and purified by recrystallization in 96% ethanol (150 mL). Isolation by filtration gave N-ethyl acetate adenopyrimidine and the product was washed thoroughly with ether. The final yield was 3.4 g (20% yield) with a melting point of 215.5-220°C. Elemental analysis results (C9H11N5O2 calculated/measured values): C: 48.65/48.86; H: 4.91/5.01; N: 31.42/31.66. Nuclear magnetic resonance hydrogen spectrum (250 MHz, DMSO-d6): δ 7.25 (broad single peak, 2H, NH), 5.06 (single peak, 2H, NCH2), 4.17 (quadruple peak , 2H, J=7.11Hz, OCH2), 1.21 (triple peak, 3H, J=7.13Hz, CH3). NMR carbon spectrum showed major peaks located at 152.70, 141.30, 61.41, 43.97 and 14.07 ppm. fast atom bombardment mass spectrometry (FAB-MS) showed molecular ion peak m/z 222 (MH+). IR spectra (cm-1, intensity): 3855 (54.3), 3274 (10.4), 3246 (14.0), 3117 (5.3), 2989 (22.3), 2940 (33.9), 2876 (43.4), 2753 (49.0), 2346 (56.1), 2106 (57.1), 1899 ( 55.7), 1762 (14.2), 1742 (14.2), 1671 (1.8), 1644 (10.9), 1606 (0.6), 1582 (7.1), 1522 (43.8), 1477 (7.2), 1445 (35.8), 1422 (8.6).
References
[1] Journal of Organic Chemistry, 1994, vol. 59, # 19, p. 5767 - 5773
[2] Tetrahedron, 2005, vol. 61, # 34, p. 8295 - 8305
[3] Journal of the Chemical Society, Perkin Transactions 1, 2000, # 1, p. 19 - 26
[4] Bioorganic and Medicinal Chemistry, 2006, vol. 14, # 7, p. 2300 - 2313
[5] Dalton Transactions, 2012, vol. 41, # 33, p. 10043 - 10051
ETHYL ADENINE-9-ACETATE Preparation Products And Raw materials
Raw materials
Preparation Products
ETHYL ADENINE-9-ACETATE Suppliers
- Tel
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- Country
- United Kingdom
- ProdList
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- Advantage
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View Lastest Price from ETHYL ADENINE-9-ACETATE manufacturers
- Product
- ETHYL ADENINE-9-ACETATE 25477-96-7
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-11
- Product
- ETHYL ADENINE-9-ACETATE 25477-96-7
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09