ChemicalBook > CAS DataBase List > 2-amino-6-methyl-4-(pyridin-3-yl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile

2-amino-6-methyl-4-(pyridin-3-yl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile

Product Name
2-amino-6-methyl-4-(pyridin-3-yl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile
CAS No.
642008-81-9
Chemical Name
2-amino-6-methyl-4-(pyridin-3-yl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile
Synonyms
BRD6989;BRD6989 (BRD-6989;BRD6989 >=98% (HPLC);2-Amino-5,6,7,8-tetrahydro-6-methyl-4-(3-pyridinyl)-3-quinolinecarbonitrile;2-amino-6-methyl-4-(pyridin-3-yl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile;CDK8,BRD 6989,Inhibitor,inhibit,CDK19,IL-10,inflammatory,BRD6989,Cyclin dependent kinase,BRD-6989,BMDCs,Interleukin Related,cortistatin-A,CDK
CBNumber
CB63760967
Molecular Formula
C16H16N4
Formula Weight
264.33
MOL File
642008-81-9.mol
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2-amino-6-methyl-4-(pyridin-3-yl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile Property

storage temp. 
2-8°C
solubility 
Soluble in DMSO
form 
powder
color 
white to beige
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML2208
Product name
BRD6989
Purity
≥98% (HPLC)
Packaging
5mg
Price
$102
Updated
2024/03/01
Sigma-Aldrich
Product number
SML2208
Product name
BRD6989
Purity
≥98% (HPLC)
Packaging
25mg
Price
$329
Updated
2024/03/01
Tocris
Product number
6438
Product name
BRD6989
Purity
≥98%(HPLC)
Packaging
10
Price
$133
Updated
2021/12/16
Tocris
Product number
6438
Product name
BRD6989
Purity
≥98%(HPLC)
Packaging
50
Price
$562
Updated
2021/12/16
TRC
Product number
B677688
Product name
BRD6989
Packaging
5mg
Price
$250
Updated
2021/12/16
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2-amino-6-methyl-4-(pyridin-3-yl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile Chemical Properties,Usage,Production

Uses

BRD 6989, is a small molecule inhibitor with high selectivity for CDK8 over CDK19. Increases IL-10 production in stimulated human and murine macrophages and dendritic cells.

Definition

ChEBI: 2-amino-6-methyl-4-(3-pyridinyl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile is a member of bipyridines.

storage

Store at +4°C

2-amino-6-methyl-4-(pyridin-3-yl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

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2-amino-6-methyl-4-(pyridin-3-yl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile Suppliers

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642008-81-9, 2-amino-6-methyl-4-(pyridin-3-yl)-5,6,7,8-tetrahydroquinoline-3-carbonitrileRelated Search:


  • 2-amino-6-methyl-4-(pyridin-3-yl)-5,6,7,8-tetrahydroquinoline-3-carbonitrile
  • BRD6989 (BRD-6989
  • 2-Amino-5,6,7,8-tetrahydro-6-methyl-4-(3-pyridinyl)-3-quinolinecarbonitrile
  • BRD6989
  • BRD6989 >=98% (HPLC)
  • CDK8,BRD 6989,Inhibitor,inhibit,CDK19,IL-10,inflammatory,BRD6989,Cyclin dependent kinase,BRD-6989,BMDCs,Interleukin Related,cortistatin-A,CDK
  • 642008-81-9