ChemicalBook > CAS DataBase List > Ethyl 2-(triphenylphosphoranylidene)propionate

Ethyl 2-(triphenylphosphoranylidene)propionate

Product Name
Ethyl 2-(triphenylphosphoranylidene)propionate
CAS No.
5717-37-3
Chemical Name
Ethyl 2-(triphenylphosphoranylidene)propionate
Synonyms
(CARBETHOXYETHYLIDENE)TRIPHENYLPHOSPHORANE;CEETPP;CEY;AURORA KA-4803;idene)triphenyL;(CarbethoxyethyL;LABOTEST-BB LT00454031;Sacubitril Impurity 81;Sacubitril/Valsartan intermediates;1-Ethoxycarbonyl-ethyliden-phosphoran
CBNumber
CB6381055
Molecular Formula
C23H23O2P
Formula Weight
362.4
MOL File
5717-37-3.mol
More
Less

Ethyl 2-(triphenylphosphoranylidene)propionate Property

Melting point:
158-162 °C (lit.)
Boiling point:
497.2±28.0 °C(Predicted)
Density 
1.14±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Crystalline Powder
color 
Yellow
Water Solubility 
Soluble in water.
Sensitive 
Air Sensitive
BRN 
757112
InChIKey
KZENFXVDPUMQOE-UHFFFAOYSA-N
CAS DataBase Reference
5717-37-3(CAS DataBase Reference)
NIST Chemistry Reference
Propanoic acid, 2-(triphenylphosphoranylidene)-, ethyl ester(5717-37-3)
More
Less

Safety

Hazard Codes 
T
Risk Statements 
36/37/38-25
Safety Statements 
45-37/39-26
RIDADR 
2811
WGK Germany 
3
HazardClass 
6.1
PackingGroup 
Ⅲ
HS Code 
29319090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
377708
Product name
(Carbethoxyethylidene)triphenylphosphorane
Purity
94%
Packaging
5g
Price
$62.2
Updated
2024/03/01
Sigma-Aldrich
Product number
377708
Product name
(Carbethoxyethylidene)triphenylphosphorane
Purity
94%
Packaging
25g
Price
$217
Updated
2024/03/01
TCI Chemical
Product number
C1641
Product name
Ethyl 2-(Triphenylphosphoranylidene)propionate
Purity
>97.0%(HPLC)
Packaging
5g
Price
$84
Updated
2024/03/01
Alfa Aesar
Product number
A15619
Product name
(1-Ethoxycarbonylethylidene)triphenylphosphorane, 97%
Packaging
10g
Price
$77.65
Updated
2024/03/01
Alfa Aesar
Product number
A15619
Product name
(1-Ethoxycarbonylethylidene)triphenylphosphorane, 97%
Packaging
25g
Price
$168.65
Updated
2024/03/01
More
Less

Ethyl 2-(triphenylphosphoranylidene)propionate Chemical Properties,Usage,Production

Chemical Properties

yellow crystalline powder

Uses

(1-Ethoxycarbonylethylidene)triphenylphosphorane is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals. It?s also a Horner-Wadsworth-Emmons reagent. It can be used for olefination. It can also be utilized for the synthesis of more complex compounds, such as (29S,37S)-isomer of malevamide E, a potent ion-channel inhibitor.

Synthesis

Ethyl 2-(triphenylphosphoranylidene)propionate was prepared this reagent from ethyl 2-bromopropanoate and triphenylphosphine.A 500-mL, one-necked, round-bottomed flask equipped with an egg-shaped magnetic stirring bar is charged with triphenylphosphine (52.46 g, 200.0 mmol), ethyl acetate (130 mL), and ethyl 2-bromopropanoate (26.03 mL, 200.0 mmol). A reflux condenser is attached to the flask and the solution is heated under reflux (oil bath temperature: 75-80 °C) under argon for 24 h. The resulting white precipitate is collected through suction filtration on a Büchner funnel and washed with ethyl acetate (100 mL). The salt is dissolved in dichloromethane (500 mL) and the solution is transferred to a 1-L separation funnel. Aqueous sodium hydroxide solution (2 M, 200 mL) is added and, after vigorously shaking, the organic and aqueous layers are separated. The aqueous phase is extracted with dichloromethane (100 mL). The combined organic phases are washed with brine, dried over anhydrous Na2SO4, filtered, and concentrated at 30 °C under rotary evaporation (20-25 mmHg); drying under vacuum (0.1-0.2 mmHg) affords 54.51 g (75.2%) of ethyl 2-(triphenylphosphoranylidene)propionate as a light-yellow solid, mp 156-158 °C.

Ethyl 2-(triphenylphosphoranylidene)propionate Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Ethyl 2-(triphenylphosphoranylidene)propionate Suppliers

Americas 1 Austria 1 Belgium 3 Canada 3 China 348 Denmark 1 Europe 1 France 4 Germany 9 Hungary 1 India 34 Japan 7 Switzerland 2 The Netherlands 3 United Kingdom 15 United States 49 Global 482
Integrity（Anhui）Biopharma Co., Ltd.
Tel
18655878467
Fax
-
Email
fayinzheng@163.com
Country
China
ProdList
37
Advantage
55
Shanghai TongYuan Chemical Co., Ltd.
Tel
021-021-69182866 13701855675
Fax
021-69182022
Email
tongyuanchem@126.com
Country
China
ProdList
4331
Advantage
58
Shandong Sihuan Pharmaceutical Co., Ltd.
Tel
0531-88993893 13335127975
Fax
QQ:787658403
Email
fairouz@sdsihuanpharm.com
Country
China
ProdList
91
Advantage
58
Creasyn Finechem(Tianjin) Co., Ltd.
Tel
022-022-83946278 13820372920
Fax
022-83945176
Email
sales@creasyn.com
Country
China
ProdList
992
Advantage
68
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40240
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2341
Advantage
56
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
BeiJing Hwrk Chemicals Limted
Tel
0757-86329057 18501085097
Fax
010-89508210
Email
sales3.gd@hwrkchemical.com
Country
China
ProdList
7639
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Shijiazhuang Sdyano Fine Chemical Co., Ltd.
Tel
0311-89250318 031166536426
Fax
4000311741
Email
master@sjzsdyn.com
Country
China
ProdList
2882
Advantage
65
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12458
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9984
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9551
Advantage
66
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
17989
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
Country
China
ProdList
42982
Advantage
64
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768850
Email
1791901229@qq.com
Country
China
ProdList
8849
Advantage
52
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12990
Advantage
57
BEST-REAGENT
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11726
Advantage
57
RYSS TECH LTD
Tel
400-188-0725 +86 21 34310725 13611771617
Fax
+86 21 34311076
Country
China
ProdList
2002
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14443
Advantage
57
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9823
Advantage
79
Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel
+8613162137806 18575662672
Fax
021 51613951
Email
mzeng@3wpharm.com
Country
China
ProdList
9746
Advantage
57
Hunan Hui Bai Shi Biotechnology Co., Ltd.
Tel
0731-85526065 13308475853
Email
ivy@hnhbsj.com
Country
China
ProdList
4550
Advantage
62
Nanjing Vital Chemical Co., Ltd.
Tel
Please Send Email 18652950785
Fax
025-87193546
Email
chemweiao@163.com
Country
China
ProdList
4388
Advantage
65
Aemon Chemical
Tel
0086-755-86198205
Email
acinfo@aemonchem.com
Country
China
ProdList
1937
Advantage
57
ZhengZhou HuaWen Chemical Co.Ltd
Tel
0370-2785118 15343847665
Fax
QQ：3470079902
Email
huawenchem@163.com
Country
China
ProdList
3205
Advantage
55
Sci General Material & Chemical Ltd
Tel
21-58388037 13472507714
Fax
0086-21-56829747 Company QQ: 1589045147
Email
1589045147@qq.com
Country
China
ProdList
675
Advantage
55
Wuhan Fortuna Chemical Co., Ltd
Tel
027-027-59207852 13308628970
Fax
QQ3130921841
Email
buy@fortunachem.com
Country
China
ProdList
2893
Advantage
58
Chengdu Ai Keda Chemical Technology Co., Ltd.
Tel
4008-755-333 18080918076
Fax
028-86757656
Email
800078821@qq.com
Country
China
ProdList
9725
Advantage
55
Shanghai civi chemical technology co.,Ltd
Tel
86-21-34053660
Fax
86-21-34053661
Email
sale@labgogo.com
Country
China
ProdList
9872
Advantage
52
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17779
Advantage
75
Beijing innoChem Science & Technology Co.,Ltd.
Tel
400-810-7969 010-59572699
Fax
010-59572688
Email
ningzi.li@inno-chem.com.cn
Country
China
ProdList
6139
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22519
Advantage
55
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
18521735133 18521732826;
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25015
Advantage
65
Sichuan Weibo Science and Technology Co., Ltd.
Tel
028-87578473
Fax
+86 (28) 8757-8473
Email
ellnn@163.com
Country
China
ProdList
50
Advantage
60
The future of Shanghai Industrial Co., Ltd.
Tel
021-61552785
Fax
021-55660885
Email
sales@shshiji.com
Country
China
ProdList
9552
Advantage
55
Shanghai Yolne Chemical Co., Ltd.
Tel
021-62960152
Fax
021-52212593
Email
934678158@qq.com
Country
China
ProdList
9906
Advantage
55
Shanghai Raise Chemical Technology Co.,Ltd
Tel
+86-021-50935922
Fax
+86-021-33847795
Country
China
ProdList
7876
Advantage
55
BeiJing Greenchem Technology Co.,Ltd.
Tel
13842764302; 13842764302
Fax
010-62925455
Email
chemrocking@bjgreenchem.com
Country
China
ProdList
461
Advantage
58
Shanghai Carlow Chemicals Co., Ltd.
Tel
21-33526724 18930996265
Fax
37023730
Email
info@carlowchem.com
Country
China
ProdList
1974
Advantage
58
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9986
Advantage
55
Huainan Kedi Chemical Factory
Tel
0554-2106669
Fax
0554-2666215
Email
sales1@kedichem.com
Country
China
ProdList
4928
Advantage
55
Bide Pharmatech Ltd.
Tel
400-1647117 15221909166
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41438
Advantage
60
Beijing Guofang Dingsheng Technology Co., Ltd.
Tel
18610472091 18610472091
Fax
010-59092859
Email
gfdskj@163.com
Country
China
ProdList
494
Advantage
58
Shanghai Worldyang Chemical Co.,Ltd.
Tel
021-021-56795766
Fax
+86-21-56795266
Email
sales@worldyachem.com
Country
China
ProdList
9352
Advantage
58
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
17994
Advantage
56
Beijing FYF Chemicals Co., Ltd
Tel
010-61647239; 15318973357
Fax
010-57903446
Email
1460285141@qq.com
Country
China
ProdList
2945
Advantage
58
Shanghai CanSpecsci Instrument Co., Ltd.
Tel
400-6087598 15021221957
Fax
4006087598-8012
Email
order@canspecsci.com
Country
China
ProdList
2071
Advantage
56
More
Less

View Lastest Price from Ethyl 2-(triphenylphosphoranylidene)propionate manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
Ethyl 2-(triphenylphosphoranylidene)propionate 5717-37-3
Price
US $1.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 tons
Release date
2020-01-14
Henan Fengda Chemical Co., Ltd
Product
(Carbethoxyethylidene)triphenylphosphorane 5717-37-3
Price
US $5.00-0.50/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-01-13
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Ethyl 2-(triphenylphosphoranylidene)propionate 5717-37-3
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-02-23

5717-37-3, Ethyl 2-(triphenylphosphoranylidene)propionateRelated Search:

Acetal Ethyl cyanoacetate Ethoxyquin Ethanol Triphenylphosphine 2-Ethoxyphenol DIETHOXYMETHANE Oxyfluorfen 2-(2-Aminoethylamino)ethanol ISOXADIFEN-ETHYL Ethyl (triphenylphosphoranylidene)acetate Phenetidine 4-Ethylacetophenone Calcium Propionate Trinexapac-ethyl Ethyl acetate Ethoxyethyne Ethyl acrylate

  • 1-CARBOETHOXYETHYLIDENE TRIPHENYLPHOSPHORANE
  • 1-CARBETHOXYETHYLIDENE TRIPHENYLPHOSPHORANE
  • (1-ETHOXYCARBONYLETHYLETHYLIDENE)TRIPHENYLPHOSPORANE
  • (1-ETHOXYCARBONYLETHYLIDENE)TRIPHENYLPHOSPHORANE
  • LABOTEST-BB LT00454031
  • (1-Carbethoxyethylidene)triphenylphosphorane~(1-Carboethoxyethylidene)triphenylphosphorane~Ethyl 2-(triphenylphosphoranylidene)propionate
  • (CARBETHOXYETHYLIDENE)TRIPHENYL-PHOSPHOR ANE, TECH., 94%
  • 1-Carbethoxyethylidene triphenylphosphorane, 97+%
  • (Carbethoxyethylidene)triphenylphosphorane, balance TPPO, ca. 94%
  • (Carbethoxyethylidine)triphenylphosphorane
  • 1-Ethoxycarbonyl-ethyliden-phosphoran
  • Ethyl 2-(triphenylphosphoranylidene)propanoate
  • Propionic acid, 2-(triphenylphosphoranylidene)-, ethyl ester
  • AURORA KA-4803
  • (CARBETHOXYETHYLIDENE)TRIPHENYLPHOSPHORANE
  • (CARBOETHOXYETHYLIDENE)TRIPHENYLPHOSPHORANE
  • CEY
  • ETHYL 2-(TRIPHENYLPHOSPHORANYLIDENE)PROPIONATE
  • (ETHOXYCARBONYLETHYLIDENE)TRIPHENYLPHOSPHORANE
  • CEETPP
  • PROPANOICACID,2-(TRIPHENYLPHOSPHORANYLIDENE)-,ETHYLESTER
  • 1-CARBETHOXYETHYLIDENE TRIPHENYLPHOSPORANE
  • (1-Ethoxycarbonylethylidene)triphenylphosphorane, 97 %
  • (Carbethoxyethylidene)triphenylphosphorane, balance TPPO
  • 2-(Triphenylphosphoranylidene)propionic acid ethyl ester
  • (Carbethoxyethylidene)triphenylphosphorane ,97%
  • (Carbethoxyethylidene)triphenylphosphorane, ca. 94%, balance tppo
  • Ethyl 2-(triphenyl-lambda5-phosphanylidene)propanoate
  • (1-Carbethoxyethylidene)triphenylphosphorane (1-Ethoxycarbonylethylidene)triphenylphosphorane 2-(Triphenylphosphoranylidene)propionic Acid Ethyl Ester
  • (Carbethoxyethylidene)triphenylphosphorane, balance TPPO, ca. 94% 5GR
  • ethyl(2-triphenylphoshoranylidene propio
  • (Carbethoxyethylidene)triphenylphosphorane 94%
  • Ethyl 2-(triphenylphosphoranylidene)propionate≥ 99% (HPLC)
  • Ethyl 2-(triphenylphosphoranylidene)propiote
  • ETHYL 2-(TRIPHENYLPHOSPHORANYLIDENE)PROPIONATEETHYL 2-(TRIPHENYLPHOSPHORANYLIDENE)PROPIONATE
  • (Ethoxycarbonylethylidene)triphenylphosphorane 95%
  • Ethyl 2-(Triphenylphosphoranylidene)propionate &gt
  • (CarbethoxyethyL
  • idene)triphenyL
  • LCZ696 intermediates，Ethyl 2- (triphenylphosphoranylidene)propionate
  • 1-ETHYLOXYCARBONYLETHYLIDENETRIPHENYLPHOSPHORANE
  • Ethyl 2-(Triphenyl-5- Phosphaneylidene) Propanoate
  • Ethyl 2-(triphenylphosphoranylidene)propanoateQ: What is Ethyl 2-(triphenylphosphoranylidene)propanoate Q: What is the CAS Number of Ethyl 2-(triphenylphosphoranylidene)propanoate Q: What is the storage condition of Ethyl 2-(triphenylphosphoranylidene)propanoate Q: What are the applications of Ethyl 2-(triphenylphosphoranylidene)propanoate
  • TIANFU-CHEM --Ethyl 2-(triphenylphosphoranylidene)propionate
  • Ethoxy formyl ethyl triphenyl phosphine
  • Carbethoxyethylidene triphenylphosphorane(CEETPP)
  • Ethoxyformyl ethylidene triphenylphosphine
  • 1-CARBETHOXYETHYLIDENE TRIPHENYL PHOSPHR
  • ETHYL-2-(TRIPHENYLPHOSPHORANYLIEDINE)PROPANOATE
  • Sacubitril Impurity 81
  • ETHYL-2- (TRIPHENYLPHOSPHORANYLIDENE)PROPIONATE 1-Carbethoxyethylidene triphenylphosphorane 1-(Ethoxycarbonyl)ethylidenetriphenylphosphorane
  • Sacubitril/Valsartan intermediates
  • Ethyl 2-(TriPhenylPhosphoranylidene) Propionat Commercial
  • 5717-37-3
  • CH3CPC6H53CO2C2H5
  • C23H23O2P
  • C-C Bond Formation
  • Olefination