5-BROMO-2-CHLORO-4-(METHYLTHIO)PYRIMIDINE

Product Name: 5-BROMO-2-CHLORO-4-(METHYLTHIO)PYRIMIDINE
CAS No.: 59549-51-8
Chemical Name: 5-BROMO-2-CHLORO-4-(METHYLTHIO)PYRIMIDINE
Synonyms: 5-Bromo-2-chloro-4-(methylthio);5-BROMO-2-CHLORO-4-(METHYLTHIO)PYRIMIDIN;5-BROMO-2-CHLORO-4-(METHYLTHIO)PYRIMIDINE;Pyrimidine, 5-bromo-2-chloro-4-(methylthio)-;5-Bromo-2-chloro-4-(methylsulfanyl)pyrimidine;5-Bromo-2-chloro-4-(methylsulphanyl)pyrimidine;5-BROMO-2-CHLORO-4-(METHYLTHIO)PYRIMIDINE ISO 9001：2015 REACH;5-Bromo-2-chloro-4-(methylsulphanyl)pyrimidine, 5-Bromo-2-chloro-4-(methylthio)-1,3-diazine
CBNumber: CB6382704
Molecular Formula: C5H4BrClN2S
Formula Weight: 239.52
MOL File: 59549-51-8.mol

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5-BROMO-2-CHLORO-4-(METHYLTHIO)PYRIMIDINE Property

Melting point:: 56-58℃
Boiling point:: 346.1±27.0 °C(Predicted)
Density: 1.83
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: -1.87±0.29(Predicted)
Appearance: White to light yellow Solid

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Safety

Hazard Codes: Xi
Hazard Note: Irritant
HS Code: 2933599590

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: B690773
Product name: 5-Bromo-2-chloro-4-(methylthio)pyrimidine
Packaging: 250mg
Price: $55
Updated: 2021/12/16

TRC

Product number: B690773
Product name: 5-Bromo-2-chloro-4-(methylthio)pyrimidine
Packaging: 1g
Price: $75
Updated: 2021/12/16

AK Scientific

Product number: Y9567
Product name: 5-Bromo-2-chloro-4-(methylthio)pyrimidine
Packaging: 250mg
Price: $87
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB159093
Product name: 5-Bromo-2-chloro-4-(methylsulfanyl)pyrimidine
Packaging: 1g
Price: $90
Updated: 2021/12/16

Matrix Scientific

Product number: 124775
Product name: 5-Bromo-2-chloro-4-(methylthio)pyrimidine
Purity: 95+%
Packaging: 1g
Price: $116
Updated: 2021/12/16

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5-BROMO-2-CHLORO-4-(METHYLTHIO)PYRIMIDINE Chemical Properties,Usage,Production

Synthesis

36082-50-5

5188-07-8

59549-51-8

General procedure for the preparation of 5-bromo-2-chloro-4-(methylthio)pyrimidine: 2 g of sodium methanethiol (28.5 mmol, 1 eq.) and 6.5 g of 5-bromo-2,4-dichloropyrimidine (28.5 mmol, 1 eq.) were reacted at room temperature with stirring for 24 hr in 50 mL of anhydrous acetonitrile. Upon completion of the reaction, the mixture was poured into water and extracted with dichloromethane, the organic phase was dried over anhydrous sodium sulfate and subsequently concentrated under reduced pressure to remove the solvent. The crude product was purified by recrystallization from hexane to give 4 g of the target compound (70% yield).1H-NMR (400 MHz, CDCl3) data: δ 8.31 (s, 1H), 2.59 (s, 3H).

References

[1] Patent: EP1878726, 2008, A1. Location in patent: Page/Page column 36
[2] Patent: US2008/176866, 2008, A1. Location in patent: Page/Page column 8
[3] Patent: WO2007/71455, 2007, A1. Location in patent: Page/Page column 252-253
[4] Patent: US2007/232632, 2007, A1. Location in patent: Page/Page column 109
[5] Bioorganic and Medicinal Chemistry Letters, 2007, vol. 17, # 22, p. 6206 - 6211

5-BROMO-2-CHLORO-4-(METHYLTHIO)PYRIMIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-BROMO-2-CHLORO-4-(METHYLTHIO)PYRIMIDINE Suppliers

China 64 India 1 Switzerland 1 United Kingdom 3 United States 10 Global 79

J & K SCIENTIFIC LTD.

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Heterochem

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Shanghai potentpharm CO.,Ltd

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Hangzhou Milestone Pharmtech Co., Ltd.

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View Lastest Price from 5-BROMO-2-CHLORO-4-(METHYLTHIO)PYRIMIDINE manufacturers

Dideu Industries Group Limited

Product: 5-BROMO-2-CHLORO-4-(METHYLTHIO)PYRIMIDINE 59549-51-8
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-12-02

Career Henan Chemical Co

Product: 5-BROMO-2-CHLORO-4-(METHYLTHIO)PYRIMIDINE 59549-51-8
Price: US $5.50/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 1kg-1000kg
Release date: 2020-01-08

59549-51-8, 5-BROMO-2-CHLORO-4-(METHYLTHIO)PYRIMIDINERelated Search:

5-Bromo-4-chloro-2-(methylthio)pyrimidine ,97%,5-Bromo-4-chloro-2-(methylthio)pyrimidine 2-CHLORO-4-METHYLSULFANYL-PYRIMIDINE 5-Bromo-2-chloropyrimidine 5-BROMO-2-CHLORO-4-(METHYLTHIO)PYRIMIDINE

5-BROMO-2-CHLORO-4-(METHYLTHIO)PYRIMIDINE

5-Bromo-2-chloro-4-(methylsulphanyl)pyrimidine

5-Bromo-2-chloro-4-(methylsulfanyl)pyrimidine

5-Bromo-2-chloro-4-(methylsulphanyl)pyrimidine, 5-Bromo-2-chloro-4-(methylthio)-1,3-diazine

5-Bromo-2-chloro-4-(methylthio)

Pyrimidine, 5-bromo-2-chloro-4-(methylthio)-

5-BROMO-2-CHLORO-4-(METHYLTHIO)PYRIMIDINE ISO 9001：2015 REACH

5-BROMO-2-CHLORO-4-(METHYLTHIO)PYRIMIDIN

59549-51-8

C5H4BrClN2S

Building Blocks

Pyrimidine