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5-BROMO-2-CHLORO-4-(METHYLTHIO)PYRIMIDINE

Product Name
5-BROMO-2-CHLORO-4-(METHYLTHIO)PYRIMIDINE
CAS No.
59549-51-8
Chemical Name
5-BROMO-2-CHLORO-4-(METHYLTHIO)PYRIMIDINE
Synonyms
5-Bromo-2-chloro-4-(methylthio);5-BROMO-2-CHLORO-4-(METHYLTHIO)PYRIMIDIN;5-BROMO-2-CHLORO-4-(METHYLTHIO)PYRIMIDINE;Pyrimidine, 5-bromo-2-chloro-4-(methylthio)-;5-Bromo-2-chloro-4-(methylsulfanyl)pyrimidine;5-Bromo-2-chloro-4-(methylsulphanyl)pyrimidine;5-BROMO-2-CHLORO-4-(METHYLTHIO)PYRIMIDINE ISO 9001:2015 REACH;5-Bromo-2-chloro-4-(methylsulphanyl)pyrimidine, 5-Bromo-2-chloro-4-(methylthio)-1,3-diazine
CBNumber
CB6382704
Molecular Formula
C5H4BrClN2S
Formula Weight
239.52
MOL File
59549-51-8.mol
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5-BROMO-2-CHLORO-4-(METHYLTHIO)PYRIMIDINE Property

Melting point:
56-58℃
Boiling point:
346.1±27.0 °C(Predicted)
Density 
1.83
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
-1.87±0.29(Predicted)
Appearance
White to light yellow Solid
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Safety

Hazard Codes 
Xi
Hazard Note 
Irritant
HS Code 
2933599590
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B690773
Product name
5-Bromo-2-chloro-4-(methylthio)pyrimidine
Packaging
250mg
Price
$55
Updated
2021/12/16
TRC
Product number
B690773
Product name
5-Bromo-2-chloro-4-(methylthio)pyrimidine
Packaging
1g
Price
$75
Updated
2021/12/16
AK Scientific
Product number
Y9567
Product name
5-Bromo-2-chloro-4-(methylthio)pyrimidine
Packaging
250mg
Price
$87
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB159093
Product name
5-Bromo-2-chloro-4-(methylsulfanyl)pyrimidine
Packaging
1g
Price
$90
Updated
2021/12/16
Matrix Scientific
Product number
124775
Product name
5-Bromo-2-chloro-4-(methylthio)pyrimidine
Purity
95+%
Packaging
1g
Price
$116
Updated
2021/12/16
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5-BROMO-2-CHLORO-4-(METHYLTHIO)PYRIMIDINE Chemical Properties,Usage,Production

Synthesis

36082-50-5

5188-07-8

59549-51-8

General procedure for the preparation of 5-bromo-2-chloro-4-(methylthio)pyrimidine: 2 g of sodium methanethiol (28.5 mmol, 1 eq.) and 6.5 g of 5-bromo-2,4-dichloropyrimidine (28.5 mmol, 1 eq.) were reacted at room temperature with stirring for 24 hr in 50 mL of anhydrous acetonitrile. Upon completion of the reaction, the mixture was poured into water and extracted with dichloromethane, the organic phase was dried over anhydrous sodium sulfate and subsequently concentrated under reduced pressure to remove the solvent. The crude product was purified by recrystallization from hexane to give 4 g of the target compound (70% yield).1H-NMR (400 MHz, CDCl3) data: δ 8.31 (s, 1H), 2.59 (s, 3H).

References

[1] Patent: EP1878726, 2008, A1. Location in patent: Page/Page column 36
[2] Patent: US2008/176866, 2008, A1. Location in patent: Page/Page column 8
[3] Patent: WO2007/71455, 2007, A1. Location in patent: Page/Page column 252-253
[4] Patent: US2007/232632, 2007, A1. Location in patent: Page/Page column 109
[5] Bioorganic and Medicinal Chemistry Letters, 2007, vol. 17, # 22, p. 6206 - 6211

5-BROMO-2-CHLORO-4-(METHYLTHIO)PYRIMIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-BROMO-2-CHLORO-4-(METHYLTHIO)PYRIMIDINE Suppliers

A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58
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View Lastest Price from 5-BROMO-2-CHLORO-4-(METHYLTHIO)PYRIMIDINE manufacturers

Dideu Industries Group Limited
Product
5-BROMO-2-CHLORO-4-(METHYLTHIO)PYRIMIDINE 59549-51-8
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-12-02
Career Henan Chemical Co
Product
5-BROMO-2-CHLORO-4-(METHYLTHIO)PYRIMIDINE 59549-51-8
Price
US $5.50/KG
Min. Order
1KG
Purity
98%min
Supply Ability
1kg-1000kg
Release date
2020-01-08

59549-51-8, 5-BROMO-2-CHLORO-4-(METHYLTHIO)PYRIMIDINERelated Search:


  • 5-BROMO-2-CHLORO-4-(METHYLTHIO)PYRIMIDINE
  • 5-Bromo-2-chloro-4-(methylsulphanyl)pyrimidine
  • 5-Bromo-2-chloro-4-(methylsulfanyl)pyrimidine
  • 5-Bromo-2-chloro-4-(methylsulphanyl)pyrimidine, 5-Bromo-2-chloro-4-(methylthio)-1,3-diazine
  • 5-Bromo-2-chloro-4-(methylthio)
  • Pyrimidine, 5-bromo-2-chloro-4-(methylthio)-
  • 5-BROMO-2-CHLORO-4-(METHYLTHIO)PYRIMIDINE ISO 9001:2015 REACH
  • 5-BROMO-2-CHLORO-4-(METHYLTHIO)PYRIMIDIN
  • 59549-51-8
  • C5H4BrClN2S
  • Building Blocks
  • Pyrimidine