(D-Ala2)-Gastric Inhibitory Polypeptide (human)
- Product Name
- (D-Ala2)-Gastric Inhibitory Polypeptide (human)
- CAS No.
- 444073-04-5
- Chemical Name
- (D-Ala2)-Gastric Inhibitory Polypeptide (human)
- Synonyms
- [D-Ala2]-GIP (human);Y（D-A）EGTFISDYSIAMDKIHQQDFVNWLLAQKGKKNDWKHNITQ;(D-Ala2)-Gastric Inhibitory Polypeptide (human);(D-Ala2)-Gastric Inhibitory Polypeptide (human) TFA;(D-Ala?)-Gastric Inhibitory Polypeptide (human) trifluoroacetate salt
- CBNumber
- CB63864308
- Molecular Formula
- C22H27NO11
- Formula Weight
- 481.44988
- MOL File
- 444073-04-5.mol
(D-Ala2)-Gastric Inhibitory Polypeptide (human) Property
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- form
- Solid
- color
- White to off-white
- Water Solubility
- Soluble to 1 mg/ml in water
N-Bromosuccinimide Price
- Product number
- 6699
- Product name
- [D-Ala2]-GIP(human)
- Packaging
- 1
- Price
- $381
- Updated
- 2021/12/16
(D-Ala2)-Gastric Inhibitory Polypeptide (human) Chemical Properties,Usage,Production
Uses
[D-Ala2]-GIP (human) is a GIP receptor agonist. [D-Ala2]-GIP (human) improves glucose tolerance. [D-Ala2]-GIP (human) shows neuroprotective activity in MPTP-induced Parkinson's disease model. [D-Ala2]-GIP (human) also improves cognitive function and hippocampal synaptic plasticity in obese diabetic rats. [D-Ala2]-GIP (human) can be used for research of type 2 diabetes, Parkinson's disease, etc[1]
storage
Store at -20°C
References
[1] Hinke SA, et al. Dipeptidyl peptidase IV-resistant [D-Ala(2)]glucose-dependent insulinotropic polypeptide (GIP) improves glucose tolerance in normal and obese diabetic rats. Diabetes. 2002 Mar;51(3):652-61. DOI:10.2337/diabetes.51.3.652
[2] Porter DW,et al. Prolonged GIP receptor activation improves cognitive function, hippocampal synaptic plasticity and glucose homeostasis in high-fat fed mice. Eur J Pharmacol. 2011 Jan 15;650(2-3):688-93. DOI:10.1016/j.ejphar.2010.10.059
[3] Verma MK, et al. Effect of D-Ala2GIP, a stable GIP receptor agonist on MPTP-induced neuronal impairments in mice. Eur J Pharmacol. 2017 Jun 5;804:38-45. DOI:10.1016/j.ejphar.2017.03.059
(D-Ala2)-Gastric Inhibitory Polypeptide (human) Preparation Products And Raw materials
Raw materials
Preparation Products
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