1-[2-[BIS[4-(TRIFLUOROMETHYL)PHENYL]METHOXY]ETHYL]-1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXYLIC ACID HYDROCHLORIDE

Product Name: 1-[2-[BIS[4-(TRIFLUOROMETHYL)PHENYL]METHOXY]ETHYL]-1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXYLIC ACID HYDROCHLORIDE
CAS No.: 110283-66-4
Chemical Name: 1-[2-[BIS[4-(TRIFLUOROMETHYL)PHENYL]METHOXY]ETHYL]-1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXYLIC ACID HYDROCHLORIDE
Synonyms: ci966;CI966HCl;CI 966 hydrochlorid;CI 966 HYDROCHLORIDE;CI-966 hydrochloride (CI966);3-pyridinecarboxylicacid,1,2,5,6-tetrahydro-1-(2-(bis(4-(trifluoromethyl)phen;1-[2-[BIS(4-(TRIFLUOROMETHYL)PHENYL)METHOXY]ETHYL]-1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXYLIC ACID;1-[2-[bis[4-(trifluoromethyl)phenyl]methoxy]ethyl]-3,6-dihydro-2H-pyridine-5-carboxylic acid hydrochloride;1-[2-bis[4-(Trifluormethyl)phenyl]methoxy]ethyl]-1,2,5,6-tetrahydropyridine3-carboxylic acid hydrochloride;1-(2-(Bis(4-(trifluoromethyl)phenyl)methoxy)ethyl)-1,2,5,6-tetrahydropyridine-3-carboxylicacidhydrochloride
CBNumber: CB6386777
Molecular Formula: C23H22ClF6NO3
Formula Weight: 509.87
MOL File: 110283-66-4.mol

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1-[2-[BIS[4-(TRIFLUOROMETHYL)PHENYL]METHOXY]ETHYL]-1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXYLIC ACID HYDROCHLORIDE Property

Melting point:: 240-244 °C
storage temp.: Desiccate at RT
solubility: Soluble to 10 mM in ethanol and to 100 mM in DMSO
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Tocris

Product number: 1296
Product name: CI966hydrochloride
Purity: ≥98%(HPLC)
Packaging: 10
Price: $216
Updated: 2021/12/16

Tocris

Product number: 1296
Product name: CI966hydrochloride
Purity: ≥98%(HPLC)
Packaging: 50
Price: $908
Updated: 2021/12/16

TRC

Product number: C475823
Product name: CI966Hydrochloride
Packaging: 2.5mg
Price: $235
Updated: 2021/12/16

Usbiological

Product number: 254973
Product name: CI 966 hydrochloride
Packaging: 10mg
Price: $466
Updated: 2021/12/16

ApexBio Technology

Product number: B6677
Product name: CI966hydrochloride
Packaging: 10mg
Price: $314
Updated: 2021/12/16

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1-[2-[BIS[4-(TRIFLUOROMETHYL)PHENYL]METHOXY]ETHYL]-1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXYLIC ACID HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

CI-966 Hydrochloride is highly selective for the cloned GABA transporter GAT-1. CI 966 Hydrochloride is a GABA transport inhibitor.

Biological Activity

Selective inhibitor of the GABA transporter GAT-1 (IC 50 values are 0.26 and 1.2 μ M at cloned human and rat GAT-1 respectively). Displays over 200-fold selectivity over GAT-2 and GAT-3. Centrally active upon systemic administration in vivo . Anticonvulsive and neuroprotective.

storage

Desiccate at RT

1-[2-[BIS[4-(TRIFLUOROMETHYL)PHENYL]METHOXY]ETHYL]-1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXYLIC ACID HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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1-[2-[BIS[4-(TRIFLUOROMETHYL)PHENYL]METHOXY]ETHYL]-1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXYLIC ACID HYDROCHLORIDE Suppliers

China 16 Europe 1 Germany 2 United Kingdom 5 United States 7 USA 1 Global 32

3B Pharmachem (Wuhan) International Co.,Ltd.

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110283-66-4, 1-[2-[BIS[4-(TRIFLUOROMETHYL)PHENYL]METHOXY]ETHYL]-1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXYLIC ACID HYDROCHLORIDERelated Search:

GUVACINE HYDROCHLORIDE 1-[4-(TRIFLUOROMETHYL)PHENYL]ETHANOL 4,4'-DIMETHYLBENZHYDROL (S)-1-[4-(TRIFLUOROMETHYL)PHENYL]ETHANOL 1-BENZYL-4-TRIFLUOROMETHYLBENZENE CHEMBRDG-BB 4017707 2-DIETHYLAMINOMETHYL-ACRYLIC ACID ARECAIDINE HYDROCHLORIDE 4-(TRIFLUOROMETHYL)BENZHYDROL 4,4'-BIS(TRIFLUOROMETHYL)BENZHYDROL (R)-1-[4-(TRIFLUOROMETHYL)PHENYL]ETHANOL 4-Methylbenzhydrol 4,4'-BIS(TRIFLUOROMETHYL)DIPHENYLMETHANE 1-[2-[BIS[4-(TRIFLUOROMETHYL)PHENYL]METHOXY]ETHYL]-1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXYLIC ACID HYDROCHLORIDE

1-[2-[bis[4-(trifluoromethyl)phenyl]methoxy]ethyl]-3,6-dihydro-2H-pyridine-5-carboxylic acid hydrochloride

3-pyridinecarboxylicacid,1,2,5,6-tetrahydro-1-(2-(bis(4-(trifluoromethyl)phen

ci966

CI 966 HYDROCHLORIDE

1-[2-[BIS(4-(TRIFLUOROMETHYL)PHENYL)METHOXY]ETHYL]-1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXYLIC ACID

1-[2-[BIS[4-(TRIFLUOROMETHYL)PHENYL]METHOXY]ETHYL]-1,2,5,6-TETRAHYDROPYRIDINE-3-CARBOXYLIC ACID HYDROCHLORIDE

1-[2-bis[4-(Trifluormethyl)phenyl]methoxy]ethyl]-1,2,5,6-tetrahydropyridine3-carboxylic acid hydrochloride

CI 966 hydrochlorid

1-(2-(Bis(4-(trifluoromethyl)phenyl)methoxy)ethyl)-1,2,5,6-tetrahydropyridine-3-carboxylicacidhydrochloride

CI966HCl

CI-966 hydrochloride (CI966)

110283-66-4

C23H21F6NO3HCl

GABA/Glycine receptor