(5-METHOXY-1H-INDOL-2-YL)PHENYLMETHANONE
- Product Name
- (5-METHOXY-1H-INDOL-2-YL)PHENYLMETHANONE
- CAS No.
- 74588-78-6
- Chemical Name
- (5-METHOXY-1H-INDOL-2-YL)PHENYLMETHANONE
- Synonyms
- D-6413;CS-888;D-64131;D 64131; D64131;D-64131(sc-203908);(5-METHOXY-1H-INDOL-2-YL)PHENYLMETHANONE;Methanone,(5-methoxy-1H-indol-2-yl)phenyl-;tubulin-inhibitory,D64131,Inhibitor,D-64131,G2/M,antiproliferative,inhibit,Microtubule/Tubulin,phase,carcinoma,antimitotic,activity,cytotoxicity,D 64131,astrocytoma
- CBNumber
- CB6390031
- Molecular Formula
- C16H13NO2
- Formula Weight
- 251.28
- MOL File
- 74588-78-6.mol
(5-METHOXY-1H-INDOL-2-YL)PHENYLMETHANONE Property
- Melting point:
- 162 °C
- Boiling point:
- 455.2±25.0 °C(Predicted)
- Density
- 1.231±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Store in freezer, under -20°C
- solubility
- Soluble in DMSO
- pka
- 14.81±0.30(Predicted)
- form
- Crystalline solid
- color
- Light yellow to yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- J65995
- Product name
- D-64131
- Packaging
- 10mg
- Price
- $154
- Updated
- 2021/12/16
- Product number
- 22944
- Product name
- D-64131
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $97
- Updated
- 2024/03/01
- Product number
- 22944
- Product name
- D-64131
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $175
- Updated
- 2024/03/01
- Product number
- 22944
- Product name
- D-64131
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $385
- Updated
- 2024/03/01
- Product number
- 22944
- Product name
- D-64131
- Purity
- ≥98%
- Packaging
- 50mg
- Price
- $577
- Updated
- 2024/03/01
(5-METHOXY-1H-INDOL-2-YL)PHENYLMETHANONE Chemical Properties,Usage,Production
Uses
Novel inhibitor of tubulin polymerization
Definition
ChEBI: (5-methoxy-1H-indol-2-yl)-phenylmethanone is a N-acylindole.
Biological Activity
Novel inhibitor of tubulin polymerization; cytotoxic and inhibits tumor cell proliferation in vitro (IC 50 = 74 nM). Prevents growth of tumor models in mice following oral administration in vivo .
References
1. beckers t, reissmann t, schmidt m et al. 2-aroylindoles, a novel class of potent, orally active small molecule tubulin inhibitors. cancer res. 2002 jun 1;62(11):3113-9.
(5-METHOXY-1H-INDOL-2-YL)PHENYLMETHANONE Preparation Products And Raw materials
Raw materials
Preparation Products
(5-METHOXY-1H-INDOL-2-YL)PHENYLMETHANONE Suppliers
- Tel
- --
- Fax
- --
- sales@alsachim.com
- Country
- France
- ProdList
- 424
- Advantage
- 0
View Lastest Price from (5-METHOXY-1H-INDOL-2-YL)PHENYLMETHANONE manufacturers
- Product
- (5-METHOXY-1H-INDOL-2-YL)PHENYLMETHANONE 74588-78-6
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 85.0-99.8%
- Supply Ability
- 20tons
- Release date
- 2020-11-05