4-FLUORO-7-AZAINDOLE

Product Name: 4-FLUORO-7-AZAINDOLE
CAS No.: 640735-23-5
Chemical Name: 4-FLUORO-7-AZAINDOLE
Synonyms: 1H-Pyrrolo[2;4-FLUORO-7-AZAINDOLE;4-Fluoro-1H-pyrrolo[2,3-b]pyridine;4-Fluoro-1H-pyrrolo[2,3-β]pyridine;1H-PYRROLO[2,3-B]PYRIDINE, 4-FLUORO-;4-FLUORO-7-AZAINDOLE ISO 9001：2015 REACH;1H-Pyrrolo[2,3-b]pyridine,4-fluoro-(9CI)
CBNumber: CB6391634
Molecular Formula: C7H5FN2
Formula Weight: 136.13
MOL File: 640735-23-5.mol

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4-FLUORO-7-AZAINDOLE Property

Melting point:: 118-120°C
Density: 1.370±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,2-8°C
solubility: Dichloromethane, Ethyl Acetate, Methanol, THF
form: Solid
pka: 13.28±0.40(Predicted)
color: Off-White to Pale Yellow
InChI: InChI=1S/C7H5FN2/c8-6-2-4-10-7-5(6)1-3-9-7/h1-4H,(H,9,10)
InChIKey: YZTWCWYRUCKWDR-UHFFFAOYSA-N
SMILES: C12NC=CC1=C(F)C=CN=2

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Safety

HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

TRC

Product number: F588000
Product name: 4-Fluoro-7-azaindole
Packaging: 100mg
Price: $60
Updated: 2021/12/16

Apolloscientific

Product number: PC201273
Product name: 4-Fluoro-7-azaindole
Purity: 97%
Packaging: 1g
Price: $211
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H32-3-2Z
Product name: 4-Fluoro-7-azaindole
Packaging: 1g
Price: $225
Updated: 2021/12/16

Matrix Scientific

Product number: 070516
Product name: 4-Fluoro-1H-pyrrolo[2,3-b]pyridine
Purity: 96%
Packaging: 1g
Price: $245
Updated: 2021/12/16

Apolloscientific

Product number: PC201273
Product name: 4-Fluoro-7-azaindole
Purity: 97%
Packaging: 5g
Price: $633
Updated: 2021/12/16

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4-FLUORO-7-AZAINDOLE Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

4-Fluoro-7-azaindole (cas# 640735-23-5) is a compound useful in organic synthesis.

Synthesis

640735-25-7

640735-23-5

Under argon protection, 4-fluoro-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine (3 g, 10 mmol) was dissolved in THF (15 mL) and cooled to 0°C. To this solution was slowly added a THF solution of tetrabutylammonium fluoride (1 M, 10.5 mL). The reaction mixture was gradually warmed to room temperature and stirred continuously for 1 hour. The progress of the reaction was monitored by TLC and after confirming complete consumption of the raw material, the reaction mixture was diluted with water (50 mL) and extracted with ethyl acetate (2 x 100 mL). The organic phases were combined, dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure. The crude product was purified by column chromatography with 20% ethyl acetate/hexane as eluent to afford 4-fluoro-1H-pyrrolo[2,3-b]pyridine (1.3 g, 94% yield) as an off-white solid.1H NMR (CDCl3, 400MHz): δ 10.52 (brs, 1H), 8.30-8.25 (m, 1H), 7.32-7.30 (m , 1H), 6.81 (dd, 1H), 6.59 (s, 1H); TLC: 20% EtOAc/hexane (Rf = 0.2).

References

[1] Organic Letters, 2003, vol. 5, # 26, p. 5023 - 5025
[2] Tetrahedron Letters, 2007, vol. 48, # 9, p. 1527 - 1529
[3] Patent: WO2017/31325, 2017, A1. Location in patent: Paragraph 0722

4-FLUORO-7-AZAINDOLE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-FLUORO-7-AZAINDOLE Suppliers

Canada 1 China 118 Europe 1 India 2 United States 17 Global 139

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View Lastest Price from 4-FLUORO-7-AZAINDOLE manufacturers

Dideu Industries Group Limited

Product: 4-FLUORO-7-AZAINDOLE 640735-23-5
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-10-26

Career Henan Chemical Co

Product: 4-FLUORO-7-AZAINDOLE 640735-23-5
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 150KG
Release date: 2019-07-09

640735-23-5, 4-FLUORO-7-AZAINDOLERelated Search:

1H-Pyrrolo[2,3-b]pyridine, 6-fluoro- 6-NITRO-1H-PYRROLO[2,3-B]PYRIDINE 4-METHYL-7-AZAINDOLE 1,7-DIDEAZAADENINE 1H-PYRROLO[2,3-B]PYRIDINE-6-CARBONITRILE 7-Azaindole 6-FLUORO-7-AZAINDOLE 5-FLUORO-7-AZAINDOLE 4-FLUORO-7-AZAINDOLE 4-FLUORO-1-(PHENYLSULFONYL)-1H-PYRROLO[2,3-B]PYRIDINE

4-FLUORO-7-AZAINDOLE

1H-PYRROLO[2,3-B]PYRIDINE, 4-FLUORO-

4-Fluoro-1H-pyrrolo[2,3-β]pyridine

4-Fluoro-1H-pyrrolo[2,3-b]pyridine

1H-Pyrrolo[2,3-b]pyridine,4-fluoro-(9CI)

1H-Pyrrolo[2

4-FLUORO-7-AZAINDOLE ISO 9001：2015 REACH

640735-23-5

C7H5N2

PYRIDINE

Indole Derivatives

Bases & Related Reagents

Nucleotides

Azaindoles