N-FORMYL-L-LEUCINE
- Product Name
- N-FORMYL-L-LEUCINE
- CAS No.
- 6113-61-7
- Chemical Name
- N-FORMYL-L-LEUCINE
- Synonyms
- NSC 334321;FOR-LEU-OH;For-L-Leu-OH;N-Formylleucine;N-ForMyl-Leu-OH;FORMYL-L-ALANINE;FORMYL-L-LEUCINE;N-Formyl-L-leucin;N-FORMYL-L-LEUCINE;N-Formyl-S-leucine
- CBNumber
- CB6399029
- Molecular Formula
- C7H13NO3
- Formula Weight
- 159.18
- MOL File
- 6113-61-7.mol
N-FORMYL-L-LEUCINE Property
- Melting point:
- 142 °C
- Boiling point:
- 284.67°C (rough estimate)
- Density
- 1.2013 (rough estimate)
- refractive index
- -39.5 ° (C=1, H2O)
- storage temp.
- -20°C
- solubility
- Ethanol (Sparingly), Methanol (Slightly)
- form
- powder
- pka
- 3.51±0.21(Predicted)
- color
- white
- Water Solubility
- 29.45g/L(temperature not stated)
- InChI
- InChI=1S/C7H13NO3/c1-5(2)3-6(7(10)11)8-4-9/h4-6H,3H2,1-2H3,(H,8,9)(H,10,11)/t6-/m0/s1
- InChIKey
- HFBHOAHFRNLZGN-LURJTMIESA-N
- SMILES
- C(O)(=O)[C@H](CC(C)C)NC=O
- CAS DataBase Reference
- 6113-61-7(CAS DataBase Reference)
Safety
- WGK Germany
- 1
- HazardClass
- IRRITANT
- HS Code
- 2924297099
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- 759945
- Product name
- N-Formyl-Leu-OH
- Purity
- 90%
- Packaging
- 1g
- Price
- $60
- Updated
- 2023/01/07
- Product number
- F0131
- Product name
- N-Formyl-L-leucine
- Packaging
- 1g
- Price
- $27
- Updated
- 2025/07/31
- Product number
- F0131
- Product name
- N-Formyl-L-leucine
- Packaging
- 5g
- Price
- $82
- Updated
- 2025/07/31
- Product number
- F700560
- Product name
- N-Formyl-L-leucine
- Packaging
- 5g
- Price
- $195
- Updated
- 2021/12/16
- Product number
- 012570
- Product name
- N-Formyl-L-leucine
- Packaging
- 1g
- Price
- $418
- Updated
- 2021/12/16
N-FORMYL-L-LEUCINE Chemical Properties,Usage,Production
Chemical Properties
White Solid
Uses
A synthetic substrate of the lipase inhibitor lipstatin.
reaction suitability
reaction type: solution phase peptide synthesis
Synthesis
64-18-6
760-84-9
5338-45-4
General procedure: L-leucine hydrochloride (1 eq.), formic acid (5 eq.), sodium bicarbonate (10 eq.) and glycerol ketone-oxide 1 (2 eq.) were dissolved in H2O (0.2-0.3 M), followed by the addition of EDCI (2 eq.). The reaction mixture was stirred for 3 h. Upon completion of the reaction, it was quenched with 1% HCl aqueous solution. The aqueous phase was extracted with EtOAc (or CHCl3, or CHCl3-MeOH (10/1). The organic extracts were combined and dried with Na2SO4, followed by vacuum evaporation of the solvent. Purification by silica gel chromatography (or Sephadex LH20) afforded N-formyl-DL-leucine (see Table 1 for yields). Similarly, the N-formylation reaction was carried out using oxide 1 in DMF-H2O (9/1).
References
[1] Tetrahedron Letters, 2013, vol. 54, # 16, p. 2077 - 2081
N-FORMYL-L-LEUCINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from N-FORMYL-L-LEUCINE manufacturers
- Product
- N-FORMYL-L-LEUCINE 6113-61-7
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98
- Supply Ability
- 10000KGS
- Release date
- 2025-11-26
- Product
- N-FORMYL-L-LEUCINE 6113-61-7
- Price
- US $10.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20 ton
- Release date
- 2024-12-05
- Product
- N-FORMYL-L-LEUCINE 6113-61-7
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1000KGS
- Release date
- 2023-04-26