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Tri(1-naphthyl)phosphine

Product Name
Tri(1-naphthyl)phosphine
CAS No.
3411-48-1
Chemical Name
Tri(1-naphthyl)phosphine
Synonyms
P(1-nap)3;Tri(1-nap;Tri(naphthalen-1-yl);tri-1-napthylphosphine;Tri(1-naphtyl)phosphine;Tri-(1-naphthyl)phosphin;TRI(1-NAPHTHYL)PHOSPHINE;TRIS(1-NAPHTHYL)PHOSPHINE;III (1-naphthyl) phosphine;rinaphthalen-1-ylphosphane
CBNumber
CB6406499
Molecular Formula
C30H21P
Formula Weight
412.46
MOL File
3411-48-1.mol
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Tri(1-naphthyl)phosphine Property

Melting point:
261-265 °C
Boiling point:
599.4±19.0 °C(Predicted)
storage temp. 
Sealed in dry,Room Temperature
form 
Powder
color 
Slightly yellow
Water Solubility 
Insoluble
CAS DataBase Reference
3411-48-1(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn
Risk Statements 
20/21/22-22-36/37/38
Safety Statements 
22-36/37/39-37/39-26-24/25
WGK Germany 
3
TSCA 
No
HS Code 
29319090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
667218
Product name
Tri-1-naphthylphosphine
Purity
97%
Packaging
1g
Price
$105
Updated
2025/07/31
Sigma-Aldrich
Product number
667218
Product name
Tri-1-naphthylphosphine
Purity
97%
Packaging
5g
Price
$186.5
Updated
2025/07/31
TCI Chemical
Product number
T4121
Product name
Tri(naphthalen-1-yl)phosphane
Packaging
1G
Price
$132
Updated
2025/07/31
Strem Chemicals
Product number
15-6610
Product name
Tri(1-naphthyl)phosphine, min. 98%
Packaging
1g
Price
$58
Updated
2024/03/01
Strem Chemicals
Product number
15-6610
Product name
Tri(1-naphthyl)phosphine, min. 98%
Packaging
5g
Price
$191
Updated
2024/03/01
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Tri(1-naphthyl)phosphine Chemical Properties,Usage,Production

Chemical Properties

Sightly yellow powder

reaction suitability

reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling
reagent type: ligand

Synthesis

90-11-9

91-20-3

13440-07-8

3411-48-1

General procedure for the synthesis of naphthalene, 1,1'-dinaphthylphosphine oxide, and tris(1-naphthyl)phosphine from 1-bromonaphthalene: To an anhydrous and degassed solution of t-BuOK (8.14 g, 72.5 mmol) in DMSO (73 mL), purged with argon and saturated with dry phosphine, an anhydrous DMSO solution of 1-bromonaphthalene (10.01 g, 48.3 mmol) was obtained ( 7 mL dropwise at 70 °C) for 1 h under stirring and continuous drumming of phosphine. The reaction mixture was heated in a stream of phosphine (70 °C) for 0.5 h. The supply of phosphine was stopped, but the mixture was stirred continuously for 1.5 h (70 °C). In the 31P NMR spectrum of the reaction mixture, the following signals were observed: -62.03 (d, 1JPH 227 Hz) for 1-Np2PH, -33.37 (s) for 1-Np3P, and -2.49 (t, 1JPH 463 Hz) for 1-NpP(O)H2, in a ratio of ~5:1.5:0.1. Trace amounts of 1,2 -Np2PH (-49.78 ppm) and 1,1,2-Np3P (-22.70 ppm). The mixture was then purged with argon, cooled and diluted with cold water (80 mL) to give a white precipitate (1.15 g). The latter was filtered out, washed with water (5 x 30 mL) and Et2O (3 x 25 mL) and dried in air to give 1-Np3P (0.68 g). The filtrate was sequentially extracted with Et2O (50 mL) and CH2Cl2 (2 × 50 mL). (a) The ether extract was washed with cold water (3 × 20 mL), dried with K2CO3, and the solvent was removed under reduced pressure to give a white waxy crude product (5.51 g), which was heated at 1 Torr (100-150 °C, sand bath) to sublimate naphthalene (1.37 g) and distill unreacted BrNp (0.95 g, 91% conversion). The residue was dissolved in EtOH (22 mL) and a white precipitate was filtered out, washed with EtOH (10 × 5 mL) and dried in vacuum to give an emulsion solid (0.62 g, 1-Np3P). After removal of the solvent and drying in vacuum, secondary phosphine oxide 1-Np2P(O)H (2.30 g) was isolated from the alcoholic extract. (b) The CH2Cl2 extract was washed with brine (10% aqueous, KCl), the orange precipitate was filtered out, dried with K2CO3, and the solvent was removed to give a white waxy product (1.21 g). The latter was heated at 1 torr (100-150 °C, sand bath) to sublimate naphthalene (0.17 g), and the residue was washed with EtOH (3 × 20 mL), 1-Np3P (0.08 g) was filtered out, and 1-Np2P(O)H (0.65 g) was removed by EtOH. the total yield of 1-Np2P(O)H was 2.95 g (45%). the total yield of 1-Np3P was 1.38g (23%). The yield of naphthalene was 1.54 g (27%).

References

[1] Tetrahedron, 2017, vol. 73, # 32, p. 4723 - 4729

Tri(1-naphthyl)phosphine Preparation Products And Raw materials

Raw materials

Preparation Products

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Tri(1-naphthyl)phosphine Suppliers

Hubei Xishaonian biotechnology co., ltd
Tel
0711-3700636 18827410479
Email
xujin@boronicgroup.com
Country
China
ProdList
50
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J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
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62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
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Beijing HwrkChemical Technology Co., Ltd
Tel
18515581800 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
9400
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Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
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Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
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Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18729
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Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12984
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57
Chengdu Ai Keda Chemical Technology Co., Ltd.
Tel
4008-755-333 18080918076
Fax
028-86757656
Email
800078821@qq.com
Country
China
ProdList
9718
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55
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View Lastest Price from Tri(1-naphthyl)phosphine manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Tri(1-naphthyl)phosphine 3411-48-1
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-02-06
Shaanxi Dideu Medichem Co. Ltd
Product
Tri(1-naphthyl)phosphine 3411-48-1
Price
US $1.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 tons
Release date
2020-01-16
Honest Joy Holdings Limited
Product
trinaphthalen-1-ylphosphane 3411-48-1
Price
US $0.00/KG
Min. Order
1KG
Purity
99.5%
Supply Ability
100 tons
Release date
2022-01-17

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