ChemicalBook > CAS DataBase List > Triphenylphosphine oxide

Triphenylphosphine oxide

Product Name
Triphenylphosphine oxide
CAS No.
791-28-6
Chemical Name
Triphenylphosphine oxide
Synonyms
TPO;TPPO;Ph3PO;TTPO;Triphenylphosphinoxid;triphenylphosphane oxide;Trisphenylphosphine oxide;Triphenyl phosphorus oxide;Orlistat Related CoMpound C;PP 560
CBNumber
CB8296821
Molecular Formula
C18H15OP
Formula Weight
278.28
MOL File
791-28-6.mol
More
Less

Triphenylphosphine oxide Property

Melting point:
150-157 °C(lit.)
Boiling point:
360 °C
Density 
1,212 g/cm3
vapor pressure 
<1 hPa (50 °C)
Flash point:
180 °C
storage temp. 
Store below +30°C.
solubility 
methanol: 25 mg/mL, clear
form 
Crystalline Powder or Flakes
color 
White to pink-brown
Specific Gravity
1.212
Water Solubility 
slightly soluble
Hydrolytic Sensitivity
4: no reaction with water under neutral conditions
BRN 
745854
LogP
2.8
CAS DataBase Reference
791-28-6(CAS DataBase Reference)
NIST Chemistry Reference
(C6H5)3PO(791-28-6)
EPA Substance Registry System
Triphenylphosphine oxide (791-28-6)
More
Less

Safety

Hazard Codes 
Xn,Xi
Risk Statements 
22-36/37/38-52/53
Safety Statements 
26-61-36
RIDADR 
3077
WGK Germany 
2
RTECS 
SZ1676000
Autoignition Temperature
590 °C
TSCA 
Yes
HazardClass 
9
PackingGroup 
III
HS Code 
29310095
Toxicity
LD50 orally in Rabbit: 685 mg/kg
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H290May be corrosive to metals

Precautionary statements

P234Keep only in original container.

P390Absorb spillage to prevent material damage.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR2544
Product name
Orlistat Related Compound C
Purity
Pharmaceutical Secondary Standard; Certified Reference Material
Packaging
50MG
Price
$602
Updated
2024/03/01
Sigma-Aldrich
Product number
1478833
Product name
Orlistat Related Compound C
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
25mg
Price
$1490
Updated
2024/03/01
Sigma-Aldrich
Product number
08902
Product name
Triphenylphosphine oxide
Purity
analytical standard
Packaging
100mg
Price
$151
Updated
2024/03/01
TCI Chemical
Product number
T0625
Product name
Triphenylphosphine Oxide
Purity
>98.0%(GC)
Packaging
25g
Price
$27
Updated
2024/03/01
TCI Chemical
Product number
T0625
Product name
Triphenylphosphine Oxide
Purity
>98.0%(GC)
Packaging
100g
Price
$58
Updated
2024/03/01
More
Less

Triphenylphosphine oxide Chemical Properties,Usage,Production

Description

Triphenylphosphine oxide (TPPO) is a coordinating solvent used to activate crystallization of chemical compounds. It has been used in flame retardant applications, as an epoxy cure catalyst, and more recently, to produce nanostructures.

Chemical Properties

White solid

Uses

Triphenylphosphine Oxide (Orlistat USP Related Compound C) is a catalyst in the conversion of aldehydes into 1,1-dichlorides. Triphenylphosphine Oxide is used as a catalyst for the synthesis of hightly functionalized α-CF3 γ-keto esters.

Uses

Triphenylphosphine oxide can be used:
As a catalyst in Appel-type chlorination reaction of acyclic primary and secondary alcohols.
As a catalyst in stereoselective poly and dibromination of α,β-unsaturated esters and β,γ-unsaturated α-ketoester compounds.
As a promotor in the diastereoselective synthesis of α-ribofuranosides through ribofuranosylation of alcohols with ribofuranosyl iodides.

Uses

Triphenylphosphine oxide is a phosphine ligand used for coupling reactions, epoxidations, and Michael reactions

Definition

ChEBI: A phosphine oxide in which the substituents on phosphorus are three phenyl groups.

Synthesis Reference(s)

Tetrahedron Letters, 31, p. 5463, 1990 DOI: 10.1016/S0040-4039(00)97873-0

Flammability and Explosibility

Not classified

Purification Methods

It crystallises from absolute EtOH and is dried in vacuo. The gold chloride complex has m 177.5-178.5o. [Addison & Sheldon J Chem Soc 2705 1956, Cox & Westheimer J Am Chem Soc 80 5441 1958, Beilstein 16 III 864, 16 1011.]

Triphenylphosphine oxide Preparation Products And Raw materials

Raw materials

Preparation Products

1-METHYLTHYMINE
More
Less

Triphenylphosphine oxide Suppliers

Austria 2 Belgium 4 China 434 China Hong Kong 1 Europe 2 France 1 Germany 9 India 28 Japan 9 Poland 1 Russia 1 Slovakia 1 Switzerland 2 The Netherlands 1 United Kingdom 14 United States 48 Global 558
Shanghai Chang-Gen Chemical Technology Co., Ltd.
Tel
021-69106814 13917161715
Email
3007500651@qq.com
Country
China
ProdList
79
Advantage
60
Dongying Shengpai Chemical Co. , Ltd.
Tel
18678649889 18678649889
Email
469278790@qq.com
Country
China
ProdList
10
Advantage
58
Hubei xingongli Chemical Co., Ltd
Tel
027-59503710 15172325309
Fax
027-59503710
Email
1400858877@qq.com
Country
China
ProdList
9967
Advantage
58
Creasyn Finechem(Tianjin) Co., Ltd.
Tel
022-022-83946278 13820372920
Fax
022-83945176
Email
sales@creasyn.com
Country
China
ProdList
1003
Advantage
68
Shanghai Boyle Chemical Co., Ltd.
Tel
021-50182298 021-50180596
Fax
+86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2210
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
BeiJing Hwrk Chemicals Limted
Tel
0757-86329057 18501085097
Fax
010-89508210
Email
sales3.gd@hwrkchemical.com
Country
China
ProdList
7583
Advantage
55
More
Less

View Lastest Price from Triphenylphosphine oxide manufacturers

Henan Fengda Chemical Co., Ltd
Product
Triphenylphosphine oxide 791-28-6
Price
US $5.00-0.50/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-01-13
Hebei Yanxi Chemical Co., Ltd.
Product
Triphenylphosphine oxide 791-28-6
Price
US $50.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
10000
Release date
2023-10-23
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Triphenylphosphine oxide 791-28-6
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-02-23

791-28-6, Triphenylphosphine oxideRelated Search:

Tri(o-tolyl)phosphine Diphenylphosphine oxide Iron oxide black Zinc oxide Triphenylantimony Rutile NITRIC OXIDE Chlorodiphenylphosphine Boron oxide Iron oxide ETHYLENE OXIDE Triphenylphosphine Tris(triphenylphosphine)ruthenium(II) chloride Triphenylphosphine-3,3',3''-trisulfonic acid trisodium salt Triphenylmethyl Chloride Triphenyl(propyl)phosphonium Orlistat USP RC E (Diethoxymethyl)diphenylphosphine oxide

  • (C6H5)3P=O
  • Trisphenylphosphine oxide
  • Orlistat USP RC C
  • Orlistat Related Compound C (25 mg) (Triphenylphosphine oxide)
  • Triphenylphosphine oxide(TPPO)
  • Triphenylphosphine oxide, 99% 100GR
  • Orlistat USP Related Compound C (Triphenylphosphine Oxide)
  • Ph3PO
  • Mouse Thrombopoietin ELISA Kit
  • Human Thrombopoietin ELISA Kit
  • Orlistat Related CoMpound C
  • PP 560
  • Triphenylphosphine oxide≥ 99.5% (Assay)
  • triphenylphosphane oxide
  • Ph3PO / Triphenylphosphine oxide
  • Phosphine oxide, triphenyl-
  • Triphenyl phosphorus oxide
  • Triphenylphosphanoxid
  • Triphenylphosphanoxide
  • triphenyl-phosphineoxid
  • triphenylphosphorusoxide
  • AURORA KA-1603
  • oxo(triphenyl)phosphorane
  • Di(phenyl)phosphorylbenzene
  • Triphenylphosphine monoxide
  • TRIPHENYLPHOSPHINE OXIDE
  • TPO
  • TriphenylphosphineOxide,>98%
  • Triphenylphosphineoxide,99%
  • TPPO: Triphenylphosphine Oxide
  • Triphenylphosphinoxid
  • TPPO
  • FR-TPPO
  • Ceftriaxone Impurity 17
  • Orlistat Impurity 3（Orlistat USP RC C）
  • Orlistat USP Related Compound C
  • Triphenylphosphine Oxide &gt
  • Triphenylphosphine oxide, 98%, for synthesis
  • Recombinant Human TPO Protein, His Tag
  • Recombinant Human Thrombopoietin/TPO Protein, His Tag & His Tag
  • Orlistat Related Compound C (25 mg)
  • TTPO
  • riphenylphosphaneoxide
  • ethyl (3S,4R,5S)-4-acetamido-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylate hydrochloride
  • triphenylphosphine oxyde
  • Alprostadil EP Impurity K
  • Orlistat Related Compound C (Triphenylphosphine Oxide)
  • Triphenylphosphine Oxide (TPPO) pure, 98.5%
  • Orlistat Related Compound C (Triphenylphosphine oxide) (1478833)
  • K.triphenylphosphineoxide.
  • Alprostadil Impurity K
  • Prostaglandin EP Impurity K
  • Prostaglandin (Alprostadil) EP Impurity K（Triphenylphosphine oxide、Oseltamivir Impurity 41）
  • Oseltamivir Impurity 3 (Triphenyl Phosphine Oxide)
  • Acrivastine TPPO
  • Oseltamivir Impurity 39 (Triphenyl Phosphine Oxide)
  • 791-28-6
  • 5980-60-8