ChemicalBook > CAS DataBase List > Triphenylphosphine oxide

Triphenylphosphine oxide

Product Name
Triphenylphosphine oxide
CAS No.
791-28-6
Chemical Name
Triphenylphosphine oxide
Synonyms
TPO;TPPO;Ph3PO;TTPO;Triphenylphosphinoxid;triphenylphosphane oxide;Trisphenylphosphine oxide;Triphenyl phosphorus oxide;Orlistat Related CoMpound C;PP 560
CBNumber
CB8296821
Molecular Formula
C18H15OP
Formula Weight
278.28
MOL File
791-28-6.mol
More
Less

Triphenylphosphine oxide Property

Melting point:
150-157 °C(lit.)
Boiling point:
360 °C
Density 
1,212 g/cm3
bulk density
400-450kg/m3
vapor pressure 
<1 hPa (50 °C)
Flash point:
180 °C
storage temp. 
Store below +30°C.
solubility 
methanol: 25 mg/mL, clear
form 
Crystalline Powder or Flakes
color 
White to pink-brown
Specific Gravity
1.212
Water Solubility 
slightly soluble
Hydrolytic Sensitivity
4: no reaction with water under neutral conditions
BRN 
745854
LogP
2.8
CAS DataBase Reference
791-28-6(CAS DataBase Reference)
NIST Chemistry Reference
(C6H5)3PO(791-28-6)
EPA Substance Registry System
Triphenylphosphine oxide (791-28-6)
More
Less

Safety

Hazard Codes 
Xn,Xi
Risk Statements 
22-36/37/38-52/53
Safety Statements 
26-61-36
RIDADR 
3077
WGK Germany 
2
RTECS 
SZ1676000
Autoignition Temperature
590 °C
TSCA 
Yes
HazardClass 
9
PackingGroup 
III
HS Code 
29310095
Toxicity
LD50 orally in Rabbit: 685 mg/kg
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H290May be corrosive to metals

Precautionary statements

P234Keep only in original container.

P390Absorb spillage to prevent material damage.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR2544
Product name
Orlistat Related Compound C
Purity
Pharmaceutical Secondary Standard; Certified Reference Material
Packaging
50MG
Price
$602
Updated
2024/03/01
Sigma-Aldrich
Product number
1478833
Product name
Orlistat Related Compound C
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
25mg
Price
$1490
Updated
2024/03/01
Sigma-Aldrich
Product number
08902
Product name
Triphenylphosphine oxide
Purity
analytical standard
Packaging
100mg
Price
$151
Updated
2024/03/01
TCI Chemical
Product number
T0625
Product name
Triphenylphosphine Oxide
Purity
>98.0%(GC)
Packaging
25g
Price
$27
Updated
2024/03/01
TCI Chemical
Product number
T0625
Product name
Triphenylphosphine Oxide
Purity
>98.0%(GC)
Packaging
100g
Price
$58
Updated
2024/03/01
More
Less

Triphenylphosphine oxide Chemical Properties,Usage,Production

Description

Triphenylphosphine oxide (TPPO) is a coordinating solvent used to activate crystallization of chemical compounds. It has been used in flame retardant applications, as an epoxy cure catalyst, and more recently, to produce nanostructures.

Chemical Properties

White solid

Uses

Triphenylphosphine Oxide (Orlistat USP Related Compound C) is a catalyst in the conversion of aldehydes into 1,1-dichlorides. Triphenylphosphine Oxide is used as a catalyst for the synthesis of hightly functionalized α-CF3 γ-keto esters.

Uses

Triphenylphosphine oxide can be used:
As a catalyst in Appel-type chlorination reaction of acyclic primary and secondary alcohols.
As a catalyst in stereoselective poly and dibromination of α,β-unsaturated esters and β,γ-unsaturated α-ketoester compounds.
As a promotor in the diastereoselective synthesis of α-ribofuranosides through ribofuranosylation of alcohols with ribofuranosyl iodides.

Uses

Triphenylphosphine oxide is a phosphine ligand used for coupling reactions, epoxidations, and Michael reactions

Definition

ChEBI: A phosphine oxide in which the substituents on phosphorus are three phenyl groups.

Synthesis Reference(s)

Tetrahedron Letters, 31, p. 5463, 1990 DOI: 10.1016/S0040-4039(00)97873-0

Flammability and Explosibility

Not classified

reaction suitability

reagent type: ligand
reaction type: Coupling Reactions
reagent type: ligand
reaction type: Epoxidations
reagent type: ligand
reaction type: Michael Reaction

Purification Methods

It crystallises from absolute EtOH and is dried in vacuo. The gold chloride complex has m 177.5-178.5o. [Addison & Sheldon J Chem Soc 2705 1956, Cox & Westheimer J Am Chem Soc 80 5441 1958, Beilstein 16 III 864, 16 1011.]

Triphenylphosphine oxide Preparation Products And Raw materials

Raw materials

Preparation Products

1-METHYLTHYMINE
More
Less

Triphenylphosphine oxide Suppliers

Austria 2 Belgium 4 China 468 China Hong Kong 1 Europe 2 France 1 Germany 9 India 28 Japan 9 Poland 1 Russia 1 Slovakia 1 Switzerland 2 The Netherlands 1 United Kingdom 14 United States 48 Global 592
BTC pharm India
Tel
+918790379245
Email
banny.janga@btcpharm.com
Country
India
ProdList
1262
Advantage
58
GLR Innovations
Tel
+91 9891111994
Email
info@glrgroup.in
Country
India
ProdList
4535
Advantage
58
TCI Chemicals (India) Pvt. Ltd.
Tel
--
Fax
--
Email
sales-in@tcichemicals.com
Country
India
ProdList
6768
Advantage
58
Chemicea Pharmaceuticals Pvt Ltd
Tel
--
Fax
--
Email
sales@chemicea.com
Country
India
ProdList
825
Advantage
58
P C Chem
Tel
--
Fax
--
Email
info@pcchemindia.in
Country
India
ProdList
675
Advantage
58
Triveni chemicals
Tel
--
Fax
--
Email
sales@trivenichemical.com
Country
India
ProdList
6088
Advantage
58
Alfa Aesar
Tel
--
Fax
--
Email
tech@alfa.com
Country
India
ProdList
6905
Advantage
58
Sisco Research Laboratories Pvt. Ltd.
Tel
--
Fax
--
Email
marketing@srlchem.com
Country
India
ProdList
4315
Advantage
58
Spectrochem Pvt., Ltd.
Tel
--
Fax
--
Email
info@spectrochem.in
Country
India
ProdList
183
Advantage
58
Pharma Affiliates
Tel
--
Fax
--
Email
@pharmaffiliates.com
Country
India
ProdList
6754
Advantage
58
Prochem Organics
Tel
--
Fax
--
Email
info@prochemorganics.com
Country
India
ProdList
30
Advantage
58
Opulent Pharma
Tel
--
Fax
--
Country
India
ProdList
810
Advantage
58
HiMedia Laboratories
Tel
--
Fax
--
Email
o@himedialabs.com
Country
India
ProdList
1841
Advantage
58
Anand Agencies
Tel
--
Fax
--
Email
en@gmail.com
Country
India
ProdList
2332
Advantage
58
Resins and Allied Products
Tel
--
Fax
--
Email
info@ranpr.com
Country
India
ProdList
14
Advantage
58
SynZeal Research Pvt Ltd
Tel
--
Fax
--
Email
standards@synzeal.com
Country
India
ProdList
6514
Advantage
58
Thykn (India) International
Tel
--
Fax
--
Email
info@thykn.com
Country
India
ProdList
89
Advantage
58
Clearsynth Labs
Tel
--
Fax
--
Email
fo@clearsynth.com
Country
India
ProdList
3887
Advantage
58
d & d chemical consultancy services
Tel
--
Fax
--
Country
India
ProdList
4
Advantage
58
Pharmaffiliates Analytics and Synthetics P. Ltd
Tel
--
Fax
--
Email
mktg@pharmaffiliates.com
Country
India
ProdList
6739
Advantage
58
A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58
Survival Technologies Pvt Ltd
Tel
--
Fax
--
Email
swami@survivaltechnologies.in
Country
India
ProdList
290
Advantage
50
OCEAN TRADING CORPORATION
Tel
--
Fax
--
Email
otcchem@otcchem.com
Country
India
ProdList
6202
Advantage
58
More
Less

View Lastest Price from Triphenylphosphine oxide manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Triphenylphosphine oxide 791-28-6
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000
Release date
2024-05-10
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Triphenylphosphine oxide 791-28-6
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-02-23
Hebei Weibang Biotechnology Co., Ltd
Product
Triphenylphosphine oxide 791-28-6
Price
US $1.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10 mt
Release date
2024-11-21

791-28-6, Triphenylphosphine oxideRelated Search:

Tri(o-tolyl)phosphine Diphenylphosphine oxide Iron oxide black Zinc oxide Triphenylantimony Rutile NITRIC OXIDE Chlorodiphenylphosphine Boron oxide Iron oxide ETHYLENE OXIDE Triphenylphosphine Tris(triphenylphosphine)ruthenium(II) chloride Triphenylphosphine-3,3',3''-trisulfonic acid trisodium salt Triphenylmethyl Chloride Triphenyl(propyl)phosphonium Orlistat USP RC E (Diethoxymethyl)diphenylphosphine oxide

  • (C6H5)3P=O
  • Trisphenylphosphine oxide
  • Orlistat USP RC C
  • Orlistat Related Compound C (25 mg) (Triphenylphosphine oxide)
  • Triphenylphosphine oxide(TPPO)
  • Triphenylphosphine oxide, 99% 100GR
  • Orlistat USP Related Compound C (Triphenylphosphine Oxide)
  • Ph3PO
  • Mouse Thrombopoietin ELISA Kit
  • Human Thrombopoietin ELISA Kit
  • Orlistat Related CoMpound C
  • PP 560
  • Triphenylphosphine oxide≥ 99.5% (Assay)
  • triphenylphosphane oxide
  • Ph3PO / Triphenylphosphine oxide
  • Phosphine oxide, triphenyl-
  • Triphenyl phosphorus oxide
  • Triphenylphosphanoxid
  • Triphenylphosphanoxide
  • triphenyl-phosphineoxid
  • triphenylphosphorusoxide
  • AURORA KA-1603
  • oxo(triphenyl)phosphorane
  • Di(phenyl)phosphorylbenzene
  • Triphenylphosphine monoxide
  • TRIPHENYLPHOSPHINE OXIDE
  • TPO
  • TriphenylphosphineOxide,>98%
  • Triphenylphosphineoxide,99%
  • TPPO: Triphenylphosphine Oxide
  • Triphenylphosphinoxid
  • TPPO
  • FR-TPPO
  • Ceftriaxone Impurity 17
  • Orlistat Impurity 3（Orlistat USP RC C）
  • Orlistat USP Related Compound C
  • Triphenylphosphine Oxide &gt
  • Triphenylphosphine oxide, 98%, for synthesis
  • Recombinant Human TPO Protein, His Tag
  • Recombinant Human Thrombopoietin/TPO Protein, His Tag & His Tag
  • Orlistat Related Compound C (25 mg)
  • TTPO
  • riphenylphosphaneoxide
  • ethyl (3S,4R,5S)-4-acetamido-5-amino-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylate hydrochloride
  • triphenylphosphine oxyde
  • Alprostadil EP Impurity K
  • Orlistat Related Compound C (Triphenylphosphine Oxide)
  • Triphenylphosphine Oxide (TPPO) pure, 98.5%
  • Orlistat Related Compound C (Triphenylphosphine oxide) (1478833)
  • K.triphenylphosphineoxide.
  • Alprostadil Impurity K
  • Prostaglandin EP Impurity K
  • Prostaglandin (Alprostadil) EP Impurity K（Triphenylphosphine oxide、Oseltamivir Impurity 41）
  • Oseltamivir Impurity 3 (Triphenyl Phosphine Oxide)
  • Acrivastine TPPO
  • Triphenylphosphine oxide in methanol
  • Triphenylphosphinoxid 100 μg/ml Methanol
  • Oseltamivir Impurity 39 (Triphenyl Phosphine Oxide)