ChemicalBook > CAS DataBase List > ETHYLTHIOUREA

ETHYLTHIOUREA

Product Name
ETHYLTHIOUREA
CAS No.
625-53-6
Chemical Name
ETHYLTHIOUREA
Synonyms
N-ETHYLTHIOUREA;Nsc62921;Ent 61326;ETHYLTHIOUREA;1-ETHYLTHIOUREA;ethyl-2-thiourea;Thiourea, ethyl-;Ethylthiourea,99%;1-ETHYL-2-THIOUREA;1-ethyl-2-thio-ure
CBNumber
CB6416447
Molecular Formula
C3H8N2S
Formula Weight
104.17
MOL File
625-53-6.mol
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ETHYLTHIOUREA Property

Melting point:
108-110 °C(lit.)
Boiling point:
132 °C
Density 
1.055 (estimate)
refractive index 
1.5500 (estimate)
storage temp. 
Store at RT
solubility 
methanol: soluble25mg/mL, clear, colorless
form 
Solid
pka
14.97±0.29(Predicted)
color 
White to Off-White
Water Solubility 
Soluble in water (24g/L).
BRN 
1699551
InChIKey
GMEHFXXZSWDEDB-UHFFFAOYSA-N
CAS DataBase Reference
625-53-6(CAS DataBase Reference)
EPA Substance Registry System
Ethylthiourea (625-53-6)
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Safety

Hazard Codes 
T
Risk Statements 
25
Safety Statements 
36/37/39-45
RIDADR 
UN 2811 6.1/PG 3
WGK Germany 
3
RTECS 
YT3700000
TSCA 
Yes
HazardClass 
6.1
PackingGroup 
III
Hazardous Substances Data
625-53-6(Hazardous Substances Data)
Toxicity
mouse,LDLo,oral,500mg/kg (500mg/kg),Teratology, The International Journal of Abnormal Development. Vol. 23, Pg. 335, 1981.
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
252530
Product name
N-Ethylthiourea
Purity
99%
Packaging
10g
Price
$208
Updated
2024/03/01
Alfa Aesar
Product number
B24761
Product name
N-Ethylthiourea, 99%
Packaging
10g
Price
$71.9
Updated
2021/12/16
Alfa Aesar
Product number
B24761
Product name
N-Ethylthiourea, 99%
Packaging
50g
Price
$253
Updated
2021/12/16
Alfa Aesar
Product number
B24761
Product name
N-Ethylthiourea, 99%
Packaging
250g
Price
$1230
Updated
2021/12/16
TRC
Product number
E926975
Product name
Ethylthiourea
Packaging
10g
Price
$110
Updated
2021/12/16
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ETHYLTHIOUREA Chemical Properties,Usage,Production

Uses

N-Ethylthiourea was used in the preparation of Re (III) complexes, which are precursors for the new rhenium complexes, potentially useful in nuclear medicine. It was also used in two-step protocol for the first chemoselective cleavage of 2-hydroxy acid amides

Definition

ChEBI: N-ethylthiourea is a member of the class of thioureas that is thiourea in which one of the hydrogens is replaced by an ethyl group. It is functionally related to a thiourea.

General Description

N-Ethylthiourea forms adduct with silver halides and their single crystal X-ray structural and spectroscopic characterizations are described.

Biological Activity

Potent, selective and reversible inhibitor of isoform II NO synthase (IC 50 = 13 nM; approximately 20- and 30-fold selective over isoforms I and III respectively).

Safety Profile

Poison by ingestion. SYN: 1-ETHYLTHIOUREA Experimental teratogenic effects. Mutation data reported. When heated to decomposition it emits toxic fumes of Sox and NOx.

Purification Methods

Crystallise the thiourea from EtOH, MeOH or ether. [Beilstein 4 IV 374.]

ETHYLTHIOUREA Preparation Products And Raw materials

Raw materials

Preparation Products

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625-53-6, ETHYLTHIOUREARelated Search:


  • 1-ethyl-2-thio-ure
  • 1-ETHYLTHIOUREA
  • 1-ETHYL-2-THIOUREA
  • Ethylthiourea,99%
  • Thiourea, ethyl-
  • ETHYLTHIOUREA
  • N-ETHYLTHIOUREA
  • N-ETHYLTHIOUREA, POLYMER-BOUND
  • N-ETHYL-2-THIOUREA
  • ethyl-2-thiourea
  • N-Ethylthiourea 99%
  • Ent 61326
  • N-Ethylthiocarbamide
  • Nsc62921
  • Urea, 1-ethyl-2-thio-
  • N-Ethylthiourea,1-Ethylthiourea
  • Thiourea, N-ethyl-
  • 625-53-6
  • H2NCSNHC2H5
  • C2H5NHCSNH2
  • Building Blocks
  • Sulfur Compounds
  • Thioureas
  • Organic Building Blocks
  • Catalysis and Inorganic Chemistry
  • Metal Scavengers
  • MetalChemical Synthesis
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  • Supported Synthesis