ChemicalBook > CAS DataBase List > 4-NITROPHENYL-ALPHA-D-GLUCOPYRANOSIDE

4-NITROPHENYL-ALPHA-D-GLUCOPYRANOSIDE

Product Name
4-NITROPHENYL-ALPHA-D-GLUCOPYRANOSIDE
CAS No.
3767-28-0
Chemical Name
4-NITROPHENYL-ALPHA-D-GLUCOPYRANOSIDE
Synonyms
Glc-a-PNP;alfa-PNPG;PNP -α-D-GLU;PNP-ALPHA-GLU;PNP-ALPHA-D-GLC;PNP-α-D-glucopyranoside;p-Nitrophenyl α-glucoside;PNP ALPHA-D-GLUCOPYRANOSIDE;p-Nitrophenol α-D-Glucoside;4-Nitrophenyl a-D-Glucoside
CBNumber
CB6418148
Molecular Formula
C12H15NO8
Formula Weight
301.25
MOL File
3767-28-0.mol
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4-NITROPHENYL-ALPHA-D-GLUCOPYRANOSIDE Property

Melting point:
210-216 °C
Boiling point:
442.39°C (rough estimate)
Density 
1.3709 (rough estimate)
refractive index 
218.5 ° (C=0.5, H2O)
storage temp. 
Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility 
DMF: 10 mg/ml,DMSO: 10 mg/ml,Ethanol: Slightly soluble,PBS (pH 7.2): 0.3 mg/ml
pka
12.55±0.70(Predicted)
form 
Crystalline Powder
color 
Off-white to light yellow
Water Solubility 
Soluble in water, warm ethanol and methanol.
BRN 
92212
InChI
InChI=1/C12H15NO8/c14-5-8-9(15)10(16)11(17)12(21-8)20-7-3-1-6(2-4-7)13(18)19/h1-4,8-12,14-17H,5H2/t8-,9-,10+,11-,12+/s3
InChIKey
IFBHRQDFSNCLOZ-ZIQFBCGOSA-N
SMILES
O(C1C=CC(N(=O)=O)=CC=1)[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |&1:10,12,15,17,19,r|
CAS DataBase Reference
3767-28-0(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
24/25-36-26
WGK Germany 
3
F 
3-10-21
HS Code 
29389090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P330Rinse mouth.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
487506
Product name
p-Nitrophenyl-α-D-glucopyranoside - CAS 3767-28-0 - Calbiochem
Purity
Chromogenic substrate for α-glucosidase.
Packaging
1g
Price
$56.2
Updated
2025/07/31
Sigma-Aldrich
Product number
487506
Product name
p-Nitrophenyl-α-D-glucopyranoside - CAS 3767-28-0 - Calbiochem
Purity
Chromogenic substrate for α-glucosidase.
Packaging
5G
Price
$214
Updated
2025/07/31
TCI Chemical
Product number
N0493
Product name
4-Nitrophenyl α-D-Glucopyranoside [Substrate for α-D-Glucosidase]
Purity
>98.0%(HPLC)
Packaging
1g
Price
$47
Updated
2025/07/31
TCI Chemical
Product number
N0493
Product name
4-Nitrophenyl α-D-Glucopyranoside [Substrate for α-D-Glucosidase]
Purity
>98.0%(HPLC)
Packaging
5g
Price
$159
Updated
2025/07/31
Sigma-Aldrich
Product number
N1377
Product name
4-Nitrophenyl α-D-glucopyranoside
Purity
≥99%
Packaging
1g
Price
$103
Updated
2025/07/31
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4-NITROPHENYL-ALPHA-D-GLUCOPYRANOSIDE Chemical Properties,Usage,Production

Chemical Properties

White Crystals

Uses

Substrate for a-glucosidase inhibitor

Uses

p-Nitrophenyl α-D-Glucopyranoside is a substrate for α-glucosidase inhibitor.

Definition

ChEBI: An alpha-D-glucoside that is beta-D-glucopyranose in which the anomeric hydroxy hydrogen is replaced by a 4-nitrophenyl group.

Biological Activity

4-Nitrophenyl ǥ-D-glucopyranoside serves as a substrate for glycosidases. Upon cleavage, the substrate is converted to a yellow-colored product.

Purification Methods

Purify 4-nitrophenyl--D-glucopyranoside by recrystallisation from H2O, MeOH or EtOH. [Jermyn Aust J Chem 7 202 1954, Montgomery et al. J Am Chem Soc 64 690 1942.] It is a chromogenic substrate from -glucosidases [Oliviera et al. Anal Biochem 1 1 3 1881981], and is a C5227substrate for glucansucrases [Binder & Robyt Carbohydr Research 124 2871983]. [Beilstein 17/7 V 53.]

4-NITROPHENYL-ALPHA-D-GLUCOPYRANOSIDE Preparation Products And Raw materials

Raw materials

Sodium acetate D(+)-Glucose Ethanol Acetic anhydride Sodium Zinc chloride Phosphorus oxitrichloride Benzenesulfonic acid, ethenyl-, polymer with diethenylbenzene Butyl acetate 4-Nitrophenol Methanol Sodium hydroxide

Preparation Products

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4-NITROPHENYL-ALPHA-D-GLUCOPYRANOSIDE Suppliers

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View Lastest Price from 4-NITROPHENYL-ALPHA-D-GLUCOPYRANOSIDE manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
4-NITROPHENYL-ALPHA-D-GLUCOPYRANOSIDE 3767-28-0
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
10000KGS
Release date
2025-05-08
WUHAN FORTUNA CHEMICAL CO., LTD
Product
4-Nitrophenyl α-D-glucopyranoside 3767-28-0
Price
US $0.00/G
Min. Order
5G
Purity
98%min
Supply Ability
30kg/month
Release date
2023-02-08
Henan Fengda Chemical Co., Ltd
Product
4-NITROPHENYL-ALPHA-D-GLUCOPYRANOSIDE 3767-28-0
Price
US $5.00-0.10/KG
Min. Order
1KG
Purity
98%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-03

3767-28-0, 4-NITROPHENYL-ALPHA-D-GLUCOPYRANOSIDERelated Search:

4-NITROPHENYL-ALPHA-D-MALTOPENTAOSIDE 4-NITROPHENYL-ALPHA-D-GLUCOPYRANOSIDE P-NITROPHENYL-ALPHA-D-MALTOSIDE BETA-GLUCOSIDASE PHENYL ALPHA-D-GLUCOPYRANOSIDE 4-Nitrophenyl6-O-(a-D-glucopyranosyl)-a-D-glucopyranoside 4-NITROPHENYL-ALPHA-D-MALTOHEXAOSIDE 4-Nitrophenyla-D-maltotetraoside 2-CHLORO-4-NITROPHENYL-2,3,4,6-TETRA-O-ACETYL-ALPHA-D-GLUCOPYRANOSIDE 4-NITROPHENYL-ALPHA-D-MALTOHEPTAOSIDE 4-NITROPHENYL-6'''''-DEOXY-6'''''-(2-PYRIDYLAMINO)-ALPHA-D-PENTA-(1->4)-GLUCOPYRANOSIDE (4-NITRO)PHENYL-2,3,4,6-TETRA-O-ACETYL-ALPHA-D-GLUCOPYRANOSIDE 4-Nitrophenyl3-O-(a-D-glucopyranosyl)-a-D-glucopyranoside 4-NITROPHENYL 2,3,4-TRI-O-ACETYL-ALPHA-D-GLUCOPYRANOSIDE 4-NITROPHENYL 2,4,6-TRI-O-ACETYL-3-O-(2,3,4,6-TETRA-O-ACETYL-B-D-GLUCOPYRANOSYL)-A-D-GLUCOPYRANOSIDE 4-Nitrophenyl4,6-benzylidene-a-D-glucopyranoside 4-Nitrophenyl2-O-(a-D-glucopyranosyl)-a-D-glucopyranoside 4-NITROPHENYL 2,3,4-TRI-O-ACETYL-6-O-ALPHA-D-GLUCOPYRANOSYL-ALPHA-D-GLUCOPYRANOSIDE

  • 4-nitrophenylalpha-glucoside
  • P-NITROPHENYL A-D-GLUCOPYRANOSIDE
  • P-NITROPHENYL ALPHA-D-GLUCOPYRANOSIDE
  • P-NITROPHENYL-ALPHA-D-GLUCOSIDE
  • PNP-ALPHA-D-GLC
  • PNP ALPHA-D-GLUCOPYRANOSIDE
  • PNP-ALPHA-GLU
  • 4'-NITROPHENYL ALPHA-D-GLUCOPYRANOSIDE
  • 4-NITROPHENYL-ALPHA-D-GLUCOPYRANOSIDE
  • 4-nitrophenyl -Α-D- glucosaMine pyranoside
  • PNP-α-D-glucopyranoside
  • 4-nitrophenyl alpha-D-glucoside
  • p-Nitrophenyl-α-D-glucopyranoside - CAS 3767-28-0 - Calbiochem
  • Glc-a-PNP
  • a-D-Glucopyranoside, 4-nitrophenyl
  • (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-(4-nitrophenoxy)oxane-3,4,5-triol
  • P-Nitrophenyl-Alpha-D-GlucopyranosideA.R.
  • .alpha.-D-Glucopyranoside, 4-nitrophenyl
  • 4-nitrophenyl-à-d-glucopyranoside
  • 4-Nitrophenyla-D-glucopyranoside
  • p-Nitrophenol α-D-Glucoside
  • 4-Nitrophenyl-ɑ-D-glucopyranoside, 98+%
  • 4-Nitrophenyl alpha-D-Glucopyranoside [Substrate for alpha-D-Glucosidase]
  • 4-Nitrophenyl a-D-Glucoside
  • p-Nitrophenol a-D-Glucoside
  • 4-Nitrophenyl-alpha-D-glucopyranoside, 98+%
  • p-Nitrophenyl α-glucoside
  • 4-Nitrophenyl-^a-D-glucopyranoside, 98+%
  • 4-Nitrophenyl α-D-glucopyranoside,p-Nitrophenyl α-D-glucopyranoside
  • [Substrate for alpha-D-Glucosidase]
  • 4-Nitrophenyl alpha-D-Glucopyranoside&nbsp
  • 4-Nitrophenyl-alpha-D-glucopyranoside, 99% 1GR
  • 4-Nitrophenyl-alpha-D-glucopyranoside, 99% 5GR
  • 4-Nitrophenyl α-D-Glucopyranoside [Substrate for α-D-Glucosidase]
  • 4-Nitrophenyl-alpha-D-glucopyranoside,99%
  • α-D-Glucopyranoside, 4-nitrophenyl
  • (2R,3S,4S,5R,6R)-2-(Hydroxymethyl)-6-(4-nitrophenoxy)tetrahydropyran-3,4,5-triol
  • 4-NITROPHENYL-ALPHA-D-GLUCOPYRANOSIDE USP/EP/BP
  • pNitrophenyl α-Dglucopyranoside
  • 4-Nitrophenyl α-D-glucopyranoside, ≥99%
  • 4-nitrophenyl α-D-glucopyranoside
  • alfa-PNPG
  • 4-Nitrophenyl-α-D-glucopyranosid
  • 4-Nitrophenyl alpha-D-glucosaminide
  • P-nitrobenzene- α- D-glucopyranoside
  • PNP -α-D-GLU
  • 4-nitrophenyl α-D-glucoside
  • (2R,3S,4S,5R,6R)-2-(Hydroxymethyl)-6-(4-nitrophenoxy)tetrahydro-2H-pyran-3,4,5-triol
  • 4'-Nitrophenyl-α-D-glucopyranoside
  • 1-O-(4-NITROPHENYL)-ALPHA-D-GLUCOSIDE
  • 4-Nitrophenyl Alpha-D-Pyranoside Glucoside (PNPG)
  • 4-Nitrophenyl α-<sc>D</sc>-glucopyranoside
  • <i>p</i>-Nitrophenyl-α-D-glucopyranoside
  • 4-Nitrobenzene- Α- D-glucopyranoside
  • 4-Nitrophenyl-alpha-D-glucopyranoside, beta-Anomer < 0.1%
  • 3767-28-0
  • Sugars
  • Glycosides