2-BROMO-N,N-DIMETHYLANILINE
- Product Name
- 2-BROMO-N,N-DIMETHYLANILINE
- CAS No.
- 698-00-0
- Chemical Name
- 2-BROMO-N,N-DIMETHYLANILINE
- Synonyms
- 2-Bromo-N,N-dimethyL;2-bromo-N,N-dimethylben;2-BroMo-N,N-diMrthylaniline;n,n-dimethyl-2-bromoaniline;2-BROMO-N,N-DIMETHYLANILINE;O-BROMO-N,N-DIMETHYLANILINE;O-BROMO-N,N'-DIMETHYLANILINE;2-broMo-N,N-diMethylbenzenaMin;(2-bromophenyl)-dimethyl-amine;1-Bromo-2-dimethylaminobenzene
- CBNumber
- CB6437839
- Molecular Formula
- C8H10BrN
- Formula Weight
- 200.08
- MOL File
- 698-00-0.mol
2-BROMO-N,N-DIMETHYLANILINE Property
- Boiling point:
- 108°C 14mm
- Density
- 1.388
- refractive index
- 1.5745
- Flash point:
- 108°C/14mm
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- form
- clear liquid
- pka
- 4.40±0.18(Predicted)
- color
- Colorless to Light orange to Yellow
- BRN
- 2205741
- InChI
- InChI=1S/C8H10BrN/c1-10(2)8-6-4-3-5-7(8)9/h3-6H,1-2H3
- InChIKey
- ONMSBNJJCUCYED-UHFFFAOYSA-N
- SMILES
- C1(N(C)C)=CC=CC=C1Br
- CAS DataBase Reference
- 698-00-0(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,N,T
- Risk Statements
- 36/37/38-42/43-50/53-40-36-33-23/24/25
- Safety Statements
- 26-36-61-60-36/37
- RIDADR
- 2810
- WGK Germany
- 3
- HazardClass
- IRRITANT
- PackingGroup
- Ⅲ
- HS Code
- 29214990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H319Causes serious eye irritation
H351Suspected of causing cancer
H373May cause damage to organs through prolonged or repeated exposure
H410Very toxic to aquatic life with long lasting effects
- Precautionary statements
-
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 590517
- Product name
- 2-Bromo-N,N-dimethylaniline
- Purity
- 97%
- Packaging
- 5g
- Price
- $24.64
- Updated
- 2025/07/31
- Product number
- B3243
- Product name
- 2-Bromo-N,N-dimethylaniline
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $64
- Updated
- 2025/07/31
- Product number
- B3243
- Product name
- 2-Bromo-N,N-dimethylaniline
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $190
- Updated
- 2025/07/31
- Product number
- B700543
- Product name
- 2-Bromo-N,N-dimethylaniline
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- J56736
- Product name
- 2-Bromo-N,N-dimethylaniline
- Packaging
- 10g
- Price
- $60
- Updated
- 2021/12/16
2-BROMO-N,N-DIMETHYLANILINE Chemical Properties,Usage,Production
Chemical Properties
Light yellow liquid
Uses
2-Bromo-N,N-dimethylaniline may be used in the synthesis of the following:
- bis[(2-dimethylamino)phenyl]amine via a multi-step reaction procedure
- 2-(N,N-dimethylaminophenyl)-bis(diethylamino)phosphine
- 6-[2-(dimethylamino)phenyl]-2,2-bipyridine obtained via lithiation followed by reaction with 2,2-bipyridine
- 1-(2′-(dimethylamino)phenyl)-2-diphenylphosphino-3-methylimidazolium trifluoromethanesulfonate via a multi-step reaction procedure
Uses
suzuki reaction
Synthesis
615-36-1
74-88-4
698-00-0
In a 250 mL round bottom flask, 4.0 g (23.3 mmol) of o-bromoaniline, 16.1 g (116.5 mmol) of anhydrous potassium carbonate, 7.3 mL (116.5 mmol) of iodomethane, and 50 mL of acetonitrile were added sequentially. The reaction mixture was heated to 70 °C and stirred at this temperature for 18 hours. Upon completion of the reaction, the mixture was cooled to room temperature. Subsequently, extraction was carried out with 100 mL of deionized water and 100 mL of diethyl ether. After separation of the organic phase, the aqueous phase was further washed with 3 x 50 mL of ether. All organic phases were combined and washed with 5 x 50 mL saturated saline. The organic phase was dried over anhydrous magnesium sulfate and then distilled under reduced pressure to remove the volatile solvent to obtain the crude product. The crude product was purified by silica gel column chromatography with the eluent of ether/hexane (5/95 v/v), resulting in 2.7 g of light yellow oily liquid product in 69% yield. The characterization data of the obtained product were consistent with those reported in the literature.
References
[1] Organic Letters, 2009, vol. 11, # 22, p. 5130 - 5133
[2] Organic Letters, 2014, vol. 16, # 14, p. 3832 - 3835
[3] Journal of Organic Chemistry, 2008, vol. 73, # 16, p. 6330 - 6340
[4] Patent: CN108586536, 2018, A. Location in patent: Paragraph 0011-0012; 0034-0036; 0038
[5] Chemische Berichte, 1907, vol. 40, p. 2528
2-BROMO-N,N-DIMETHYLANILINE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-BROMO-N,N-DIMETHYLANILINE manufacturers
- Product
- 2-Bromo-N,N-dimethylaniline 698-00-0
- Price
- US $2.20-8.80/kg
- Min. Order
- 1kg
- Purity
- 99%min
- Supply Ability
- 100kg
- Release date
- 2025-08-29
- Product
- 2-bromo-N,N-dimethylaniline 698-00-0
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- Customise
- Release date
- 2025-08-16
- Product
- 2-BROMO-N,N-DIMETHYLANILINE 698-00-0
- Price
- US $750.00/KG
- Min. Order
- 1KG
- Purity
- 99
- Supply Ability
- 10000KG
- Release date
- 2020-11-09