GGTI-298

Product Name: GGTI-298
CAS No.: 180977-44-0
Chemical Name: GGTI-298
Synonyms: CS-2228;GGTI-298;GGTI298 (GGTI-298;GGTI-298 free base;GGTI298 (CF3CO2H)salt;GGTI-298 trifluoroacetate salt;N-4-[2(R)-AMINO-3-MERCAPTOPROPYL]AMINO-2-NAPHTHYLBENZOYL-(L)-LEUCINE METHYL ESTER, TFA;L-Leucine, N-[4-[[(2R)-2-amino-3-mercaptopropyl]amino]-2-(1-naphthalenyl)benzoyl]-, methyl ester;(S)-Methyl 2-(4-(((R)-2-amino-3-mercaptopropyl)amino)-2-(naphthalen-1-yl)benzamido)-4-methylpentanoate;N-[[4-(2-(R)-AMINO-3-MERCAPTOPROPYL)AMINO]-2-NAPHTHYLBENZOYL]LEUCINE METHYL ESTER TRIFLUOROACETATE SALT
CBNumber: CB6450528
Molecular Formula: C27H33N3O3S
Formula Weight: 479.63
MOL File: Mol file

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GGTI-298 Property

Melting point:: 99.5-100 °C
Boiling point:: 673.7±55.0 °C(Predicted)
Density: 1.190±0.06 g/cm3(Predicted)
storage temp.: −20°C
solubility: DMSO: 22 mg/mL
form: solid
pka: 9.83±0.10(Predicted)
color: off-white

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris

Product number: 2430
Product name: GGTI298
Purity: ≥95%(HPLC)
Packaging: 1
Price: $212
Updated: 2021/12/16

Usbiological

Product number: 255374
Product name: GGTI 298
Packaging: 1mg
Price: $460
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb611699
Product name: GGTI298
Packaging: 5mg
Price: $555.9
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: INB0001112
Product name: GGTI-298
Purity: 95.00%
Packaging: 0.25MG
Price: $599.45
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb611699
Product name: GGTI298
Packaging: 1mg
Price: $306
Updated: 2021/12/16

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GGTI-298 Chemical Properties,Usage,Production

Uses

GGTI 298 is a CAAX peptidomimetic that selectively inhibits geranylgeranyltransferase I (GGTase I). It has been shown to arrest human tumor cells and induce apoptosis.

Definition

ChEBI: (2S)-2-[[[4-[[(2R)-2-amino-3-mercaptopropyl]amino]-2-(1-naphthalenyl)phenyl]-oxomethyl]amino]-4-methylpentanoic acid methyl ester is a leucine derivative.

GGTI-298 Preparation Products And Raw materials

Raw materials

Preparation Products

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GGTI-298 Suppliers

China 57 Japan 2 Switzerland 1 United Kingdom 2 United States 10 Global 72

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15848
Advantage: 69

VDM Biochemicals

Tel: 0330-2528181
Fax: 0330-2528171
Email: sales@vdmbio.com
Country: United States
ProdList: 510
Advantage: 64

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51471
Advantage: 80

Shanghai Chaolan Chemical Technology Center

Tel: QQ:65489617 15618227136
Fax: 21-5161 9052
Email: info@SuperLan-chem.com
Country: China
ProdList: 9737
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 12308
Advantage: 58

Musechem

Tel: +1-800-259-7612
Fax: +1-800-259-7612
Email: info@musechem.com
Country: United States
ProdList: 4662
Advantage: 60

Twochem Co.Ltd.

Tel: 021-58111628 15800915896
Fax: QQ 3285589261
Country: China
ProdList: 1988
Advantage: 58

Jinan Yaoyan Pharmaceutical Co., Ltd.

Tel
Fax: -
Email: jnyaoyan@163.com
Country: China
ProdList: 3069
Advantage: 58

Fan De(Beijing) Biotechnology Co., Ltd.

Tel: 15911056312
Email: liming@bio-fount.com
Country: China
ProdList: 9730
Advantage: 58

Nanjing Meihao Pharmaceutical Technology Co., Ltd.

Tel: meitaochem@126.com
Email: meitaochem@126.com
Country: China
ProdList: 19105
Advantage: 58

180977-44-0, GGTI-298Related Search:

GGTI-298

N-[[4-(2-(R)-AMINO-3-MERCAPTOPROPYL)AMINO]-2-NAPHTHYLBENZOYL]LEUCINE METHYL ESTER TRIFLUOROACETATE SALT

N-4-[2(R)-AMINO-3-MERCAPTOPROPYL]AMINO-2-NAPHTHYLBENZOYL-(L)-LEUCINE METHYL ESTER, TFA

GGTI-298 trifluoroacetate salt

N-[[4-(2-(R)-Amino-3-mercaptopropyl)amino]-2-naphthylbenzoyl]leucine methyl ester trifluoroacetate salt

N-[4-[2(R)-Amino-3-mercaptopropyl]amino-2-(1-naphthalenyl)benzoyl]-L-leucinemethylestertrifluoroacetatesalt

GGTI298 (CF3CO2H)salt

CS-2228

GGTI298 (GGTI-298

methyl (2S)-2-[[4-[[(2R)-2-amino-3-sulfanylpropyl]amino]-2-naphthalen-1-ylbenzoyl]amino]-4-methylpentanoate,2,2,2-trifluoroacetic acid

L-Leucine, N-[4-[[(2R)-2-amino-3-mercaptopropyl]amino]-2-(1-naphthalenyl)benzoyl]-, methyl ester

GGTI-298 free base

(S)-Methyl 2-(4-(((R)-2-amino-3-mercaptopropyl)amino)-2-(naphthalen-1-yl)benzamido)-4-methylpentanoate

180977-44-0

C27H33N3O3SC2HF3O2

C27H33N3O3SCF3CO2H

A cell-permeable, prodrug form of the GGTase I inhibitor GGTI-297.