CHEMBRDG-BB 9070752
- Product Name
- CHEMBRDG-BB 9070752
- CAS No.
- 719282-11-8
- Chemical Name
- CHEMBRDG-BB 9070752
- Synonyms
- AKOS BC-3333;CHEMBRDG-BB 9070752;5-ACETAMIDO-2-CHLOROBENZOIC ACID;5-(Acetylamino)-2-Chlorobenzoic Acid;2-Chloro-5-(acetylamino)benzoic acid;Benzoic acid, 5-(acetylamino)-2-chloro-;5-(acetylamino)-2-chlorobenzoic acid(SALTDATA: FREE)
- CBNumber
- CB6452188
- Molecular Formula
- C9H8ClNO3
- Formula Weight
- 213.62
- MOL File
- 719282-11-8.mol
CHEMBRDG-BB 9070752 Property
- storage temp.
- Sealed in dry,Room Temperature
- Appearance
- Brown to black Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B400628
- Product name
- 5-Acetamido-2-chlorobenzoicAcid
- Packaging
- 500mg
- Price
- $200
- Updated
- 2021/12/16
- Product number
- FA52904
- Product name
- 5-(Acetylamino)-2-Chlorobenzoic Acid
- Packaging
- 2g
- Price
- $200.6
- Updated
- 2021/12/16
- Product number
- FA52904
- Product name
- 5-(Acetylamino)-2-Chlorobenzoic Acid
- Packaging
- 5G
- Price
- $320.9
- Updated
- 2021/12/16
- Product number
- FA52904
- Product name
- 5-(Acetylamino)-2-Chlorobenzoic Acid
- Packaging
- 500mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- 5742AH
- Product name
- 5-(Acetylamino)-2-chlorobenzoicacid
- Packaging
- 1g
- Price
- $104
- Updated
- 2021/12/16
CHEMBRDG-BB 9070752 Chemical Properties,Usage,Production
Uses
5-Acetamido-2-chlorobenzoic Acid is used for preparation of 2-amino-5-substituted pyrimidine kinase inhibitors and use in therapy.
Synthesis
89-54-3
75-36-5
719282-11-8
1. In a dry reaction flask, 5-amino-2-chlorobenzoic acid (0.50 g, 2.9 mmol) was dissolved in dichloromethane (15 mL). 2. Acetyl chloride (0.30 mL, 4.2 mmol) and triethylamine (1.2 mL, 8.6 mmol) were added sequentially to the above solution. 3. The reaction mixture was stirred at room temperature for 2 h. When the reaction was complete, the mixture was slowly poured into water. 4. The aqueous phase was extracted with ethyl acetate and the organic layers were combined. 5. The combined organic layers were washed sequentially with water and saturated saline. 6. 6. The organic layer was dried over anhydrous sodium sulfate and filtered to remove the desiccant. 7. The filtrate was concentrated under pressure to give 5-(acetylamino)-2-chlorobenzoic acid (0.17 g, 27% yield) as a brown solid.
References
[1] Patent: WO2008/8234, 2008, A1. Location in patent: Page/Page column 115
CHEMBRDG-BB 9070752 Preparation Products And Raw materials
Raw materials
Preparation Products
CHEMBRDG-BB 9070752 Suppliers
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 0371-88888888 272369594
- Fax
- QQ:272369594
- 2723695949@qq.com
- Country
- China
- ProdList
- 4954
- Advantage
- 50
- Tel
- 021-61312847; 18021002903
- Fax
- QQ:3008007432
- 3008007409@qq.com
- Country
- China
- ProdList
- 71826
- Advantage
- 60
- Tel
- 571-89925085
- Fax
- 0086-571-89925065
- sales@amadischem.com
- Country
- China
- ProdList
- 131957
- Advantage
- 58
- Tel
- 021-20432229
- Fax
- QQ2412110556
- 2412110556@qq.com
- Country
- China
- ProdList
- 6017
- Advantage
- 55
- Tel
- 0512-56316828
- Fax
- 0512-56316826
- info@amateksci.com
- Country
- China
- ProdList
- 28785
- Advantage
- 58
- Tel
- 022-59987777 13552403979
- jia_guoqiang@wuxiapptec.com
- Country
- China
- ProdList
- 22345
- Advantage
- 58
- Tel
- 025-58859352 18068836627
- Fax
- (5)02557626880
- dt3@aikonchem.com
- Country
- China
- ProdList
- 15493
- Advantage
- 58
- Tel
- +86-27-50766799 +8618062016861
- contact@labnetwork.com
- Country
- China
- ProdList
- 19987
- Advantage
- 58
- Tel
- 021-58461859 15821823057
- service@aiviche.com
- Country
- China
- ProdList
- 49312
- Advantage
- 58