ChemicalBook > CAS DataBase List > PYRAZINE-2-CARBOXAMIDINE HYDROCHLORIDE

PYRAZINE-2-CARBOXAMIDINE HYDROCHLORIDE

Product Name: PYRAZINE-2-CARBOXAMIDINE HYDROCHLORIDE
CAS No.: 138588-41-7
Chemical Name: PYRAZINE-2-CARBOXAMIDINE HYDROCHLORIDE
Synonyms: AIDS070607;AIDS-070607;BUTTPARK 32\03-57;pyrazine-2-carboximidamide;pyrazinamidine hydrochloride;PYRAZINE-2-CARBOXAMIDINE HCL;2-pyrazinecarboxamidine hydrochloride;PYRAZINE-2-CARBOXAMIDINE HYDROCHLORIDE;PYRAZINE-2-CARBOXIMIDAMIDE HYDROCHLORIDE;Pyrazine-2-carboximidamide monohydrochloride
CBNumber: CB6457613
Molecular Formula: C5H7ClN4
Formula Weight: 158.59
MOL File: 138588-41-7.mol

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PYRAZINE-2-CARBOXAMIDINE HYDROCHLORIDE Property

storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
form: solid
color: White
CAS DataBase Reference: 138588-41-7(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 22
HazardClass: IRRITANT
HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: P840883
Product name: Pyrazine-2-carboxamidineHydrochloride
Packaging: 10g
Price: $200
Updated: 2021/12/16

Apolloscientific

Product number: OR3402
Product name: Pyrazine-2-carboxamidinehydrochloride
Purity: 97%
Packaging: 25g
Price: $182
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H41-5-X4
Product name: Pyrazine-2-carboxamidinehydrochloride
Purity: 97%
Packaging: 25g
Price: $200
Updated: 2021/12/16

AK Scientific

Product number: R154
Product name: Pyrazine-2-carboximidamide
Packaging: 5g
Price: $109
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H41-5-X4
Product name: Pyrazine-2-carboxamidinehydrochloride
Purity: 97%
Packaging: 10g
Price: $109
Updated: 2021/12/16

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PYRAZINE-2-CARBOXAMIDINE HYDROCHLORIDE Chemical Properties,Usage,Production

Synthesis

19847-12-2

138588-41-7

The general procedure for the synthesis of 2-pyrazinamidine hydrochloride from 2-cyanopyrazine was as follows: 2-cyanopyrazine (1.00 kg, 9.53 mol) was slowly added to a solution of sodium methanol (NaOCH3, 51.4 g, 0.952 mol) in methanol (3800 mL) at room temperature. The reaction mixture was heated to 30 °C and stirred for 6 hours. Upon completion of the reaction, the mixture was cooled to 25 °C, followed by the addition of ammonium chloride (NH4Cl, 572 g, 10.5 mol). Stirring of the reaction mixture was continued for 22 hours. At the end of the reaction, methyl tert-butyl ether (4000 mL) was added and stirred for 15 minutes to promote solid formation. The solid product was collected by filtration and washed with methyl tert-butyl ether (2 x 1000 mL). Finally, the product was dried at 40 °C, 0-10 mmHg for 17 h to give the white solid product 2-pyrazinamidine hydrochloride (1435 g) in 95% yield and 95% purity by HPLC.1H NMR (DMSO-D6) data were as follows: δ 9.7 (broad single peak, 3H), 9.49 (double peak, 1H, J=1.5Hz), 9.04 (multiple peaks, 1H), 8.93 (multiple peaks, 1H), 9.04 (multiple peaks, 1H), 8.93 (multiple peaks 1H), 8.93 (triple peak, 1H, J=1.5Hz).

References

[1] Patent: US2006/281760, 2006, A1. Location in patent: Page/Page column 5; 8
[2] Bioorganic and Medicinal Chemistry, 2009, vol. 17, # 1, p. 111 - 118
[3] Patent: US2005/75357, 2005, A1. Location in patent: Page/Page column 35
[4] Patent: WO2005/79798, 2005, A1. Location in patent: Page/Page column 150
[5] Bioorganic and Medicinal Chemistry Letters, 2010, vol. 20, # 1, p. 299 - 301

PYRAZINE-2-CARBOXAMIDINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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PYRAZINE-2-CARBOXAMIDINE HYDROCHLORIDE Suppliers

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View Lastest Price from PYRAZINE-2-CARBOXAMIDINE HYDROCHLORIDE manufacturers

Career Henan Chemical Co

Product: PYRAZINE-2-CARBOXAMIDINE HYDROCHLORIDE 138588-41-7
Price: US $3.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 100KG
Release date: 2020-03-13

138588-41-7, PYRAZINE-2-CARBOXAMIDINE HYDROCHLORIDERelated Search:

PYRAZINE-2-CARBOXAMIDINE HYDROCHLORIDE N'-HYDROXY-2-PYRAZINECARBOXIMIDAMIDE Pyrazine Formamidine hydrochloride BU 239 HYDROCHLORIDE PYRAZINE-2-CARBOXIMIDOHYDRAZIDE Pyrazinecarboximidamide,3-chloro-N-hydroxy- 3-CHLORO-N'-([(4-CHLOROANILINO)CARBONYL]OXY)PYRAZINE-2-CARBOXIMIDAMIDE o2-(4-Chlorobenzoyl)-3-chloropyrazine-2-carboximidamide 3-CHLORO-N'-(([4-(TRIFLUOROMETHOXY)ANILINO]CARBONYL)OXY)PYRAZINE-2-CARBOXIMIDAMIDE 4-Amino-1,7-diethyl-6-methylpyrazino(2,3-c)(1,2,6)thiadiazine 2,2-diox ide O2-[3-(TRIFLUOROMETHYL)BENZOYL]-3-CHLOROPYRAZINE-2-CARBOHYDROXIMAMIDE N-HYDROXY-PYRAZINE-2-CARBOXAMIDINE RARECHEM BG FB 0001 O2-(4-CHLOROBENZOYL)-3-CHLOROPYRAZINE-2-CARBOHYDROXIMAMIDE N'-[(2-CHLOROACETYL)OXY]-2-PYRAZINECARBOXIMIDAMIDE o2-[3-(Trifluoromethyl)benzoyl]-3-chloropyrazine-2-carboximidamide O2-[(2-CHLORO-4-PYRIDYL)CARBONYL]PYRAZINE-2-CARBOHYDROXIMAMIDE

PYRAZINE-2-CARBOXIMIDAMIDE HYDROCHLORIDE

PYRAZINE-2-CARBOXAMIDINE HCL

PYRAZINE-2-CARBOXAMIDINE HYDROCHLORIDE

BUTTPARK 32\03-57

pyrazine-2-carboximidamide

Pyrazine-2-carboximidamide monohydrochloride

pyrazinamidine hydrochloride

Pyrazine-2-carboximidamide hydrochloride, 2-Carbamimidoyl-1,4-diazine hydrochloride

(amino-pyrazin-2-yl-methylene)ammonium chloride

(amino-pyrazin-2-ylmethylidene)azanium chloride

(amino-pyrazin-2-yl-methylidene)azanium chloride

[amino-(2-pyrazinyl)methylene]ammonium chloride

2-pyrazinecarboxamidine hydrochloride

AIDS070607

AIDS-070607

2-Pyrazinecarboximidamide, hydrochloride (1:1)

138588-41-7

Pyrazines, Pyrimidines & Pyridazines

pharmacetical

Pyrazines, Pyrimidines & Pyridazines

Pyrazine