6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-CYCLOPROPYL]-NICOTINIC ACID

Product Name: 6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-CYCLOPROPYL]-NICOTINIC ACID
CAS No.: 153559-76-3
Chemical Name: 6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-CYCLOPROPYL]-NICOTINIC ACID
Synonyms: LG 268;CD 3127;lg100268;ALRT 268;LGD 1268;AGN 192620;LGD 100268;hthalenyl)cyclopropyl)-;3-pyridinecarboxylicacid,6-(1-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-nap;6-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)cyclopropyl]nicotinic Acid
CBNumber: CB6458625
Molecular Formula: C24H29NO2
Formula Weight: 363.49
MOL File: 153559-76-3.mol

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6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-CYCLOPROPYL]-NICOTINIC ACID Property

Melting point:: 275-277°C
Boiling point:: 487.0±33.0 °C(Predicted)
Density: 1.115±0.06 g/cm3(Predicted)
storage temp.: -20°C
solubility: DMSO: ≥5mg/mL (warmed)
pka: 2.35±0.10(Predicted)
form: powder
color: white to beige

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0279
Product name: LG100268
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $144
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML0279
Product name: LG100268
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $568
Updated: 2024/03/01

Cayman Chemical

Product number: 21606
Product name: LG 100268
Purity: ≥98%
Packaging: 1mg
Price: $44
Updated: 2024/03/01

Cayman Chemical

Product number: 21606
Product name: LG 100268
Purity: ≥98%
Packaging: 5mg
Price: $118
Updated: 2024/03/01

Cayman Chemical

Product number: 21606
Product name: LG 100268
Purity: ≥98%
Packaging: 10mg
Price: $214
Updated: 2024/03/01

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6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-CYCLOPROPYL]-NICOTINIC ACID Chemical Properties,Usage,Production

Chemical Properties

Off-White Solid

Uses

LG 100268 is a potent RXR agonist for evaluation in the treatment of non-insulin-dependent (type II) diabetes mellitus (NIDDM).

Biochem/physiol Actions

LG100268 (LG268) is a potent and selective rexinoid and retinoid-X receptor (RXR) agonist. LG100268 binds to the α, β and γ RXR receptors with an IC50 = 3-4 nM and has no activity at the RAR retinoic acid receptors.

storage

Store at -20°C

6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-CYCLOPROPYL]-NICOTINIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-CYCLOPROPYL]-NICOTINIC ACID Suppliers

Canada 1 China 36 India 1 United Kingdom 1 United States 10 Global 49

153559-76-3, 6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-CYCLOPROPYL]-NICOTINIC ACIDRelated Search:

6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-CYCLOPROPYL]-NICOTINIC ACID 6-TERT-BUTYL-3-FORMYLPYRIDINE 1,4,6,7-TETRAMETHYL-1,2,3,4-TETRAHYDRONAPHTHALENE 1,2,4-TRI-ISO-PROPYLBENZENE METHYL 6-(1-(1,2,3,4-TETRAHYDRO-1,1,4,4,6-PENTAMETHYLNAPHTHALEN-7-YL)CYCLOPROPYL)PYRIDINE-3-CARBOXYLATE

2-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)cyclopropyl]pyridine-5-carboxylic acid

6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-CYCLOPROPYL]-NICOTINIC ACID

6-[1-(3,5,5,8,8-PentaMethyl-5,6,7,8-tetrahydronaphthalen-2-yl)cyclopropyl]pyridine-3-carboxylic acid

3-Pyridinecarboxylicacid,6-[1-(5,6,7,8-tetrahydro-3,5,5,8,8-pentaMethyl-2-naphthalenyl)cyclopropyl]-

3-pyridinecarboxylicacid,6-(1-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-nap

hthalenyl)cyclopropyl)-

lg100268

6-[1-(3,5,5,8,8-PENTAMETHYL-5,6,7,8-TETRAHYDRO-NAPHTHALEN-2-YL)-CYCLOPROPYL]-NICOTINIC ACID (FOR R&D ONLY)

6-[1-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)cyclopropyl]- 3-Pyridinecarboxylic Acid

AGN 192620

ALRT 268

CD 3127

LG 268

LGD 100268

LGD 1268

6-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)cyclopropyl]nicotinic Acid

153559-76-3

Intermediates & Fine Chemicals

Pharmaceuticals

Retinoids