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PF-1163B

Product Name
PF-1163B
CAS No.
258871-60-2
Chemical Name
PF-1163B
Synonyms
PF-1163B;(-)-PF1163B;3S-[[4-(2-hydroxyethoxy)phenyl]methyl]-4,10R-dimethyl-13R-pentyl-1-oxa-4-azacyclotridecane-2,5-dione;1-Oxa-4-azacyclotridecane-2,5-dione, 3-[[4-(2-hydroxyethoxy)phenyl]methyl]-4,10-dimethyl-13-pentyl-, (3S,10R,13R)-
CBNumber
CB64666576
Molecular Formula
C27H43NO5
Formula Weight
461.63
MOL File
258871-60-2.mol
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PF-1163B Property

Boiling point:
649.9±50.0 °C(Predicted)
Density 
1.027±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
form 
An oil
pka
14.26±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
22066
Product name
PF-1163B
Purity
≥95%
Packaging
500μg
Price
$189
Updated
2024/03/01
Cayman Chemical
Product number
22066
Product name
PF-1163B
Purity
≥95%
Packaging
2.5mg
Price
$752
Updated
2024/03/01
AK Scientific
Product number
3563CC
Product name
CID489140
Packaging
2.5mg
Price
$937
Updated
2021/12/16
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PF-1163B Chemical Properties,Usage,Production

Description

PF-1163B is an antifungal agent produced by Penicillium sp. II. PF-1163B inhibits ergosterol (ERG) synthesis (IC50 = 34 ng/ml). PF-1163B showed potent growth inhibitory activity against pathogenic fungal strain Candida albicans but did not show cytotoxic activity against mammalian cells.

Definition

ChEBI: PF 1163B is a macrolide antibiotic that is 4,10-dimethyl-1-oxa-4-azacyclotridecane-2,5-dione substituted by a 4-(2-hydroxyethoxy)benzyl group at position 3 and a pentyl group at position 13 (the 3S,10R,13S stereoisomer). It is isolated from Penicillium sp.PF1163 and exhibits antifungal activity against the pathogenic fungal strain Candida albicans TIMM1768. It has a role as an antifungal agent and a Penicillium metabolite. It is a macrolide antibiotic, a lactam and an aromatic ether.

PF-1163B Preparation Products And Raw materials

Raw materials

Preparation Products

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PF-1163B Suppliers

Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6870
Advantage
58
Meng Cheng Technology (Shanghai) Co., LTD
Tel
400-820-6829
Email
sales@mitachieve.com
Country
China
ProdList
8864
Advantage
58
Nanjing Tengyi Biotechnology Co., Ltd
Tel
025-58851786 17714337195
Email
sales@tybiochem.com
Country
China
ProdList
5597
Advantage
58
Shanghai Yifei Biotechnology Co. , Ltd.
Tel
021-65675885 18964387627
Email
customer_service@efebio.com
Country
China
ProdList
11975
Advantage
58
Shanghai Hao Zhun Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
info@zzsrm.com
Country
CHINA
ProdList
6846
Advantage
58

258871-60-2, PF-1163BRelated Search:


  • PF-1163B
  • (-)-PF1163B
  • 1-Oxa-4-azacyclotridecane-2,5-dione, 3-[[4-(2-hydroxyethoxy)phenyl]methyl]-4,10-dimethyl-13-pentyl-, (3S,10R,13R)-
  • 3S-[[4-(2-hydroxyethoxy)phenyl]methyl]-4,10R-dimethyl-13R-pentyl-1-oxa-4-azacyclotridecane-2,5-dione
  • 258871-60-2