PF-1163B
- Product Name
- PF-1163B
- CAS No.
- 258871-60-2
- Chemical Name
- PF-1163B
- Synonyms
- PF-1163B;(-)-PF1163B;3S-[[4-(2-hydroxyethoxy)phenyl]methyl]-4,10R-dimethyl-13R-pentyl-1-oxa-4-azacyclotridecane-2,5-dione;1-Oxa-4-azacyclotridecane-2,5-dione, 3-[[4-(2-hydroxyethoxy)phenyl]methyl]-4,10-dimethyl-13-pentyl-, (3S,10R,13R)-
- CBNumber
- CB64666576
- Molecular Formula
- C27H43NO5
- Formula Weight
- 461.63
- MOL File
- 258871-60-2.mol
PF-1163B Property
- Boiling point:
- 649.9±50.0 °C(Predicted)
- Density
- 1.027±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- form
- An oil
- pka
- 14.26±0.10(Predicted)
N-Bromosuccinimide Price
- Product number
- 22066
- Product name
- PF-1163B
- Purity
- ≥95%
- Packaging
- 500μg
- Price
- $189
- Updated
- 2024/03/01
- Product number
- 22066
- Product name
- PF-1163B
- Purity
- ≥95%
- Packaging
- 2.5mg
- Price
- $752
- Updated
- 2024/03/01
- Product number
- 3563CC
- Product name
- CID489140
- Packaging
- 2.5mg
- Price
- $937
- Updated
- 2021/12/16
PF-1163B Chemical Properties,Usage,Production
Description
PF-1163B is an antifungal agent produced by Penicillium sp. II. PF-1163B inhibits ergosterol (ERG) synthesis (IC50 = 34 ng/ml). PF-1163B showed potent growth inhibitory activity against pathogenic fungal strain Candida albicans but did not show cytotoxic activity against mammalian cells.
Definition
ChEBI: PF 1163B is a macrolide antibiotic that is 4,10-dimethyl-1-oxa-4-azacyclotridecane-2,5-dione substituted by a 4-(2-hydroxyethoxy)benzyl group at position 3 and a pentyl group at position 13 (the 3S,10R,13S stereoisomer). It is isolated from Penicillium sp.PF1163 and exhibits antifungal activity against the pathogenic fungal strain Candida albicans TIMM1768. It has a role as an antifungal agent and a Penicillium metabolite. It is a macrolide antibiotic, a lactam and an aromatic ether.
PF-1163B Preparation Products And Raw materials
Raw materials
Preparation Products
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