RP 001 (hydrochloride)

Product Name: RP 001 (hydrochloride)
CAS No.: 1781880-34-9
Chemical Name: RP 001 (hydrochloride)
Synonyms: RP001 hydrochloride,RP 001 hydrochloride;N-[4-[5-[3-cyano-4-(1-methylethoxy)phenyl]-1,2,4-oxadiazol-3-yl]-2,3-dihydro-1H-inden-1-yl]-β-alanine,monohydrochloride
CBNumber: CB64666596
Molecular Formula: C24H25ClN4O4
Formula Weight: 468.94
MOL File: 1781880-34-9.mol

More

Less

RP 001 (hydrochloride) Property

storage temp.: Store at -20°C
solubility: DMSO: 100 mM
form: A solid
color: White to off-white

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

Cayman Chemical

Product number: 16636
Product name: RP 001 (hydrochloride)
Purity: ≥98%
Packaging: 1mg
Price: $37
Updated: 2024/03/01

Cayman Chemical

Product number: 16636
Product name: RP 001 (hydrochloride)
Purity: ≥98%
Packaging: 5mg
Price: $161
Updated: 2024/03/01

Cayman Chemical

Product number: 16636
Product name: RP 001 (hydrochloride)
Purity: ≥98%
Packaging: 10mg
Price: $249
Updated: 2024/03/01

Cayman Chemical

Product number: 16636
Product name: RP 001 (hydrochloride)
Purity: ≥98%
Packaging: 25mg
Price: $530
Updated: 2024/03/01

TRC

Product number: R700988
Product name: RP001Hydrochloride
Packaging: 50mg
Price: $975
Updated: 2021/12/16

More

Less

RP 001 (hydrochloride) Chemical Properties,Usage,Production

Description

RP 001 is a potent sphingosine-1-phosphate receptor 1 (S1P₁) agonist (EC₅₀ = 9 pM). It is competitive with W146 , a selective S1P₁ antagonist, and induces internalization and polyubiquitination of S1P₁ in a dose-dependent manner. RP 001 induces dose-dependent lymphopenia in mice (EC₅₀ = 0.03 mg/kg). It reduces S1P₁-EGFP expression ex vivo on lymphocytes in the isolated lymph node of Edg1^eGFP/eGFP mice but has no effect in vivo. RP 001 also completely inhibits M. stadtmanae (MSS) rechallenge-induced enlargement of B cell-rich tertiary lymphoid tissues (TLTs) and reduces neutrophil accumulation in the airways of a mouse model of experimental hypersensitivity pneumonitis.

Uses

RP 001 Hydrochloride is a picomolar, short-acting S1P1 agonist.

in vivo

RP-001 hydrochloride causes dose-dependent rapid lymphopenia with an EC₅₀ of 0.03 mg/kg^[1].

storage

Store at -20°C

RP 001 (hydrochloride) Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

RP 001 (hydrochloride) Suppliers

China 9 United States 4 Global 13

Shanghai Beckham Medical Technology Co., Ltd

Tel: 13816613772
Fax: QQ: 12922499
Email: huahero21@sina.com
Country: China
ProdList: 2391
Advantage: 55

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9803
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11218
Advantage: 58

TargetMol Chemicals Inc.

Tel: 15002134094
Email: marketing@targetmol.cn
Country: China
ProdList: 29496
Advantage: 58

R&D Systems, Inc

Tel: 18003437475
Fax: 1-612-656-4400
Email: rdname@qq.com
Country: China
ProdList: 6960
Advantage: 58

Cayman Chemical Company

Tel: 800-364-9897
Email: sales@caymanchem.com
Country: China
ProdList: 6838
Advantage: 58

Biosynth Biological Technology (Suzhou) Co Ltd

Tel: 51288865780
Email: sales@biosynth.com
Country: China
ProdList: 6051
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354;
Email: support@targetmol.com
Country: United States
ProdList: 39035
Advantage: 58

Aladdin Scientific

Tel
Email: tp@aladdinsci.com
Country: United States
ProdList: 52923
Advantage: 58

1781880-34-9, RP 001 (hydrochloride)Related Search:

RP001 hydrochloride,RP 001 hydrochloride

N-[4-[5-[3-cyano-4-(1-methylethoxy)phenyl]-1,2,4-oxadiazol-3-yl]-2,3-dihydro-1H-inden-1-yl]-β-alanine,monohydrochloride

1781880-34-9