RP 001 (hydrochloride)

Product Name: RP 001 (hydrochloride)
CAS No.: 1781880-34-9
Chemical Name: RP 001 (hydrochloride)
Synonyms: RP001 hydrochloride,RP 001 hydrochloride;N-[4-[5-[3-cyano-4-(1-methylethoxy)phenyl]-1,2,4-oxadiazol-3-yl]-2,3-dihydro-1H-inden-1-yl]-β-alanine,monohydrochloride
CBNumber: CB64666596
Molecular Formula: C24H25ClN4O4
Formula Weight: 468.94
MOL File: 1781880-34-9.mol

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RP 001 (hydrochloride) Property

storage temp.: Store at -20°C
solubility: DMSO: 100 mM
form: A solid

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 16636
Product name: RP 001 (hydrochloride)
Purity: ≥98%
Packaging: 1mg
Price: $37
Updated: 2024/03/01

Cayman Chemical

Product number: 16636
Product name: RP 001 (hydrochloride)
Purity: ≥98%
Packaging: 5mg
Price: $161
Updated: 2024/03/01

Cayman Chemical

Product number: 16636
Product name: RP 001 (hydrochloride)
Purity: ≥98%
Packaging: 10mg
Price: $249
Updated: 2024/03/01

Cayman Chemical

Product number: 16636
Product name: RP 001 (hydrochloride)
Purity: ≥98%
Packaging: 25mg
Price: $530
Updated: 2024/03/01

TRC

Product number: R700988
Product name: RP001Hydrochloride
Packaging: 50mg
Price: $975
Updated: 2021/12/16

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RP 001 (hydrochloride) Chemical Properties,Usage,Production

Description

RP 001 is a potent sphingosine-1-phosphate receptor 1 (S1P₁) agonist (EC₅₀ = 9 pM). It is competitive with W146 , a selective S1P₁ antagonist, and induces internalization and polyubiquitination of S1P₁ in a dose-dependent manner. RP 001 induces dose-dependent lymphopenia in mice (EC₅₀ = 0.03 mg/kg). It reduces S1P₁-EGFP expression ex vivo on lymphocytes in the isolated lymph node of Edg1^eGFP/eGFP mice but has no effect in vivo. RP 001 also completely inhibits M. stadtmanae (MSS) rechallenge-induced enlargement of B cell-rich tertiary lymphoid tissues (TLTs) and reduces neutrophil accumulation in the airways of a mouse model of experimental hypersensitivity pneumonitis.

Uses

RP 001 Hydrochloride is a picomolar, short-acting S1P1 agonist.

storage

Store at -20°C

RP 001 (hydrochloride) Preparation Products And Raw materials

Raw materials

Preparation Products

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RP 001 (hydrochloride) Suppliers

China 6 United States 4 Global 10

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9804
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32159
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11218
Advantage: 58

Changzhou Furuisi Biotechnology Co., Ltd

Tel: 0519-85524369
Email: 3477467573@qq.com
Country: China
ProdList: 8617
Advantage: 58

TargetMol Chemicals Inc.

Tel: 15002134094
Email: marketing@targetmol.cn
Country: China
ProdList: 19699
Advantage: 58

R&D Systems, Inc

Tel: 18003437475 18003437475
Fax: 1-612-656-4400
Email: rdname@qq.com
Country: China
ProdList: 35733
Advantage: 58

TargetMol Chemicals Inc.

Tel
Email: support@targetmol.com
Country: United States
ProdList: 38630
Advantage: 58

Aladdin Scientific

Tel
Email: tp@aladdinsci.com
Country: United States
ProdList: 52924
Advantage: 58

1781880-34-9, RP 001 (hydrochloride)Related Search:

RP001 hydrochloride,RP 001 hydrochloride

N-[4-[5-[3-cyano-4-(1-methylethoxy)phenyl]-1,2,4-oxadiazol-3-yl]-2,3-dihydro-1H-inden-1-yl]-β-alanine,monohydrochloride

1781880-34-9