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SEMBL

Product Name
SEMBL
CAS No.
1443448-82-5
Chemical Name
SEMBL
Synonyms
SEMBL;2-hydroxy-N-[(3S)-4-methylene-5-oxo-tetrahydrofuran-3-yl]benzamide;Benzamide, 2-hydroxy-N-[(3S)-tetrahydro-4-methylene-5-oxo-3-furanyl]-;SEMBL (S)-beta-Salicyloylamino-alpha-exo-methylene-gamma- butyrolactone
CBNumber
CB64668499
Molecular Formula
C12H11NO4
Formula Weight
233.22
MOL File
1443448-82-5.mol
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SEMBL Property

Boiling point:
536.7±50.0 °C(Predicted)
Density 
1.36±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
pka
8.29±0.30(Predicted)
form 
Solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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SEMBL Chemical Properties,Usage,Production

Uses

SEMBL is a potent NF-κB inhibitor. SEMBL can inhibit NF-κB-DNA binding, and also inhibits NF-κB-dependent inflammatory cytokine secretions. SEMBL inhibits cancer cell migration and invasion via decreasing MMP expression. SEMBL can be used for researching anticancer[1].

References

[1] Umezawa K, et al. Inhibition of matrix metalloproteinase expression and cellular invasion by NF-κB inhibitors of microbial origin. Biochim Biophys Acta Proteins Proteom. 2020;1868(6):140412. DOI:10.1016/j.bbapap.2020.140412

SEMBL Preparation Products And Raw materials

Raw materials

Preparation Products

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SEMBL Suppliers

Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696,15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4768
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55
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
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58
ShangHai Biochempartner Co.,Ltd
Tel
177-54423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
8000
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62
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
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58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Tel
86-571-88216897,88216896 13588875226
Fax
86-571-88216895
Email
sales@hzclap.com
Country
CHINA
ProdList
6312
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58
Changzhou Chenhong Biotechnology Co., Ltd.
Tel
+86-0519-85788828 +86-13775037613
Email
sales@chemrenpharm.com
Country
China
ProdList
3934
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58
Shanghai Kaiwei Chemical Technology Co., Ltd.
Tel
021-58461859 15821823057
Email
service@aiviche.com
Country
China
ProdList
49312
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58
Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd
Tel
15317229551
Fax
QQ:3607245178
Email
15151849396@163.com
Country
China
ProdList
989
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58
ShangHai ChuanQian Chemcial Technique Centre
Tel
15869524721
Email
3525679403@qq.com
Country
China
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4989
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58
cjbscvictory
Tel
13348960310
Email
3003867561@qq.com
Country
China
ProdList
10503
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1443448-82-5, SEMBLRelated Search:


  • SEMBL
  • Benzamide, 2-hydroxy-N-[(3S)-tetrahydro-4-methylene-5-oxo-3-furanyl]-
  • SEMBL (S)-beta-Salicyloylamino-alpha-exo-methylene-gamma- butyrolactone
  • 2-hydroxy-N-[(3S)-4-methylene-5-oxo-tetrahydrofuran-3-yl]benzamide
  • 1443448-82-5