ChemicalBook > CAS DataBase List > SEMBL
SEMBL
- Product Name
- SEMBL
- CAS No.
- 1443448-82-5
- Chemical Name
- SEMBL
- Synonyms
- SEMBL;2-hydroxy-N-[(3S)-4-methylene-5-oxo-tetrahydrofuran-3-yl]benzamide;Benzamide, 2-hydroxy-N-[(3S)-tetrahydro-4-methylene-5-oxo-3-furanyl]-;SEMBL (S)-beta-Salicyloylamino-alpha-exo-methylene-gamma- butyrolactone
- CBNumber
- CB64668499
- Molecular Formula
- C12H11NO4
- Formula Weight
- 233.22
- MOL File
- 1443448-82-5.mol
More
Less
SEMBL Property
- Boiling point:
- 536.7±50.0 °C(Predicted)
- Density
- 1.36±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- pka
- 8.29±0.30(Predicted)
- form
- Solid
- color
- White to off-white
More
Less
SEMBL Chemical Properties,Usage,Production
Uses
SEMBL is a potent NF-κB inhibitor. SEMBL can inhibit NF-κB-DNA binding, and also inhibits NF-κB-dependent inflammatory cytokine secretions. SEMBL inhibits cancer cell migration and invasion via decreasing MMP expression. SEMBL can be used for researching anticancer[1].
References
[1] Umezawa K, et al. Inhibition of matrix metalloproteinase expression and cellular invasion by NF-κB inhibitors of microbial origin. Biochim Biophys Acta Proteins Proteom. 2020;1868(6):140412. DOI:10.1016/j.bbapap.2020.140412
SEMBL Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
SEMBL Suppliers
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32435
- Advantage
- 58
- Tel
- +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 19961
- Advantage
- 58