UPCDC30245

Product Name
UPCDC30245
CAS No.
1883351-01-6
Chemical Name
UPCDC30245
Synonyms
UPCDC30245;UPCDC30245 >=98% (HPLC);1-Piperazineethanamine, N-[1-[3-(5-fluoro-1H-indol-2-yl)phenyl]-4-piperidinyl]-4-(1-methylethyl)-
CBNumber
CB64670658
Molecular Formula
C28H38FN5
Formula Weight
463.63
MOL File
1883351-01-6.mol
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UPCDC30245 Property

Boiling point:
647.6±55.0 °C(Predicted)
Density 
1.20±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
form 
powder
pka
16.22±0.30(Predicted)
color 
white to beige
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML1674
Product name
UPCDC30245
Purity
≥98% (HPLC)
Packaging
5MG
Price
$131
Updated
2023/06/20
Sigma-Aldrich
Product number
SML1674
Product name
UPCDC30245
Purity
≥98% (HPLC)
Packaging
25MG
Price
$530
Updated
2023/06/20
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UPCDC30245 Chemical Properties,Usage,Production

Biochem/physiol Actions

UPCDC30245 is an allosteric inhibitor of AAA ATPase p97, also called valosine containing protein (VCP). p97 is an integral component of the ubiquitin fusion degradation (UFD) pathway. It plays a role in degradation of misfolded proteins, Golgi membrane reassembly, membrane transport, myofibril assembly, autophagosome maturation, and cell division, and is overexpressed in many tumor types. UPCDC30245 has an IC50 value of 27 nM, and has been shown to bind at the junction between the D1 and D2 domains of p97. UPCDC30245 has been used in cryo-ECM to show how such inhibitor binding prevents the confomational changes necessary for p97 function.

UPCDC30245 Preparation Products And Raw materials

Raw materials

Preparation Products

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UPCDC30245 Suppliers

China 7 United States 1 Global 8
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
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80
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Tel
86-571-88216897,88216896 13588875226
Fax
86-571-88216895
Email
sales@hzclap.com
Country
CHINA
ProdList
6312
Advantage
58
DC Chemicals
Tel
021-58447131 13564518121
Email
sales@dcchemicals.com
Country
China
ProdList
9410
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58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing1@energy-chemical.com
Country
China
ProdList
44808
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58
Beijing Biocreative Technology Co., Ltd.
Tel
15522676233
Email
3007606172@qq.com
Country
China
ProdList
1248
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58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24648
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58
Nanjing Shizhou Biology Technology Co.,Ltd
Tel
025-85560043 15850508050
Fax
025-85563444
Email
cindy.huang@synzest.com
Country
China
ProdList
12005
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TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38466
Advantage
58

1883351-01-6, UPCDC30245Related Search:


  • UPCDC30245
  • UPCDC30245 >=98% (HPLC)
  • 1-Piperazineethanamine, N-[1-[3-(5-fluoro-1H-indol-2-yl)phenyl]-4-piperidinyl]-4-(1-methylethyl)-
  • 1883351-01-6