ChemicalBook > CAS DataBase List > Risdiplam

Risdiplam

Product Name
Risdiplam
CAS No.
1825352-65-5
Chemical Name
Risdiplam
Synonyms
RG7916;2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)-7-(4,7-diazaspiro[2.5]octan-7-yl)-4H-pyrido[1,2-a]pyrimidin-4-one;Lispran;RO7034067;Risdiplam;Risdiplam (RG7916);Risdiplam (RG-7916, RO-7034067);7-amino-2,3-dihydro-1H-inden-4-ol;RG 7916,Inhibitor,RG-7916,Risdiplam,RO 7034067,DNA/RNA Synthesis,RO-7034067,inhibit;7-(4,7-diazaspiro[2.5]octan-7-yl)-2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)pyrido[1,2-a]pyrimidin-4-one
CBNumber
CB64674494
Molecular Formula
C22H23N7O
Formula Weight
401.46
MOL File
1825352-65-5.mol
More
Less

Risdiplam Property

Density 
1.50±0.1 g/cm3(Predicted)
solubility 
Soluble in DMSO
pka
9.41±0.20(Predicted)
form 
solid
color 
Light yellow to yellow
InChI
InChI=1S/C22H23N7O/c1-14-9-18(26-29-11-15(2)24-21(14)29)17-10-20(30)28-12-16(3-4-19(28)25-17)27-8-7-23-22(13-27)5-6-22/h3-4,9-12,23H,5-8,13H2,1-2H3
InChIKey
ASKZRYGFUPSJPN-UHFFFAOYSA-N
SMILES
C12C=CC(N3CC4(CC4)NCC3)=CN1C(=O)C=C(C1=NN3C=C(C)N=C3C(C)=C1)N=2
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Cayman Chemical
Product number
29028
Product name
Risdiplam
Packaging
5mg
Price
$116
Updated
2024/03/01
Cayman Chemical
Product number
29028
Product name
Risdiplam
Packaging
25mg
Price
$353
Updated
2024/03/01
Cayman Chemical
Product number
29028
Product name
Risdiplam
Packaging
1mg
Price
$37
Updated
2024/03/01
Cayman Chemical
Product number
29028
Product name
Risdiplam
Packaging
10mg
Price
$213
Updated
2024/03/01
ChemScene
Product number
CS-0039501
Product name
Risdiplam
Purity
99.35%
Packaging
10mg
Price
$250
Updated
2021/12/16
More
Less

Risdiplam Chemical Properties,Usage,Production

Description

Risdiplam is a survival of motor neuron 2 (SMN2) splicing modifier.

Chemical Properties

light yellow powder to yellow powder

Uses

Risdiplam is used in preparation of Imidazopyridazinyl Pyridopyrimidinones for treating spinal muscular atrophy. Gene splicing modulator.

Side effects

Body aches or pain, chest pain or tightness, chills, cough, ear congestion, fever, headache, loss of voice, runny or stuffy nose, sneezing, sore throat, trouble breathing, unusual tiredness or weakness and so on.

storage

0-4℃ for short term (days to weeks) or -20℃ for long term (months)

Risdiplam Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Risdiplam Suppliers

Zhengzhou Converging Chemical Co. LTD
Tel
0371-0371-53399770 18037166334
Email
2853031800@qq.com
Country
China
ProdList
3253
Advantage
58
Shanghai Changyu Medical Technology Co. Ltd.
Tel
+86-13301875428
Email
sales@changyuhe.com
Country
China
ProdList
307
Advantage
58
Xuzhou Maikai Biotechnology Co., Ltd.
Tel
13921770081
Email
SVP01@magicbiotech.cn
Country
China
ProdList
511
Advantage
58
Jilin Lianben Technology Development Co., Ltd
Tel
13756693631
Fax
0432-62601618
Email
sunting@lianben.com
Country
China
ProdList
46
Advantage
58
Biopole Pharmatech Co., Ltd.
Tel
0512-65974739-0 15151475053
Email
mengqi_biopole@163.com
Country
China
ProdList
45
Advantage
58
Hubei Kailong Biotechnology Co.,Ltd.
Tel
19526384105
Email
3671394075@qq.com
Country
China
ProdList
2864
Advantage
58
Zhengzhou Runkai Pharmaceutical Technology Co., Ltd
Tel
19137044811; 19137644811
Email
shisx1211@163.com
Country
China
ProdList
504
Advantage
58
Jinan Good Medical &Technology Ltd Co.,
Tel
+86-0086-531-55562571,18953105926 +86-13553167512
Email
935170726@qq.com
Country
China
ProdList
75
Advantage
58
Chembest Research Laboratories Limited
Tel
+86-21-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6005
Advantage
61
Nanjing Sunlida Biological Technology Co., Ltd.
Tel
025-57798810
Fax
025-57019371
Email
sales@sunlidabio.com
Country
China
ProdList
3239
Advantage
55
More
Less

View Lastest Price from Risdiplam manufacturers

Jinan Good Medical Technology Co.,Ltd
Product
Risdiplam 1825352-65-5
Price
US $0.00/g
Min. Order
5g
Purity
99%
Supply Ability
10, 000grams
Release date
2024-09-03
Apeloa production Co.,Limited
Product
Risdiplam 1825352-65-5
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
10000
Release date
2024-06-05
Hebei Yanxi Chemical Co., Ltd.
Product
Risdiplam 1825352-65-5
Price
US $0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20tons
Release date
2023-10-08

1825352-65-5, RisdiplamRelated Search:


  • 7-amino-2,3-dihydro-1H-inden-4-ol
  • Risdiplam
  • RO7034067
  • RG7916
  • 4H-Pyrido[1,2-a]pyrimidin-4-one, 7-(4,7-diazaspiro[2.5]oct-7-yl)-2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)-
  • 2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)-7-(4,7-diazaspiro[2.5]octan-7-yl)-4H-pyrido[1,2-a]pyrimidin-4-one
  • Risdiplam (RG-7916, RO-7034067)
  • RG 7916,Inhibitor,RG-7916,Risdiplam,RO 7034067,DNA/RNA Synthesis,RO-7034067,inhibit
  • 2-(4,6-dimethylpyrrolo[1,2-b]pyridazin-2-yl)-7-(4,7-diazaspiro[2.5]octan-7-yl)-4H-pyrido[1,2-a]pyrimidin-4-one
  • 7-(4,7-diazaspiro[2.5]octan-7-yl)-2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)pyrido[1,2-a]pyrimidin-4-one
  • Risdiplam (RG7916)
  • Lispran
  • 1825352-65-5
  • 1825352-65-6