T-2 TOXIN

ChemicalBook > CAS DataBase List > T-2 TOXIN

Product Name: T-2 TOXIN
CAS No.: 21259-20-1
Chemical Name: T-2 TOXIN
Synonyms: toxint2;Toxin T 2;hothecene;nsc138780;T-2 TOXIN;T-2 toxins;alerate[qr];FUSARITOXIN;t-2mycotoxin;Insariotoxin
CBNumber: CB6469458
Molecular Formula: C24H34O9
Formula Weight: 466.53
MOL File: 21259-20-1.mol

Less

T-2 TOXIN Property

Melting point:: 151.5℃
alpha: D26 +15° (c = 2.58 in ethanol)
Boiling point:: 489.35°C (rough estimate)
Density: 1.1942 (rough estimate)
refractive index: 1.6230 (estimate)
Flash point:: 2 °C
storage temp.: −20°C
solubility: DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml; Ethanol: 20 mg/ml
form: powder
pka: 13.24±0.70(Predicted)
color: white
Merck: 13,9872
IARC: 3 (Vol. 31, Sup 7) 1987

Less

Safety

Hazard Codes: T+,T,Xn,F
Risk Statements: 26/27/28-38-36-20/21/22-11
Safety Statements: 28-36/37-45-36-26-16-36/37/39-22
RIDADR: UN 3462 6.1/PG 1
WGK Germany: 3
RTECS: YD0100000
F: 10-21
HazardClass: 6.1(a)
PackingGroup: I
HS Code: 29329990
Hazardous Substances Data: 21259-20-1(Hazardous Substances Data)
Toxicity: LD50 orally in female rats: 4.0 mg/kg (Marasas); LD50 (mg/kg) in mice: 5.2 i.p., 4.2 i.v.; in rats: 7.0 intragastric, 0.9-1.3 i.p., 0.9 i.v., 2.0 s.c.; in guinea pigs: 3.0-4.0 orally, 5.3 intragastric, 1.0 i.m., 1.0-2.0 i.v., 1.0-2.0 s.c.; in pigs: 5.0 orally, 3.0 i.v. (Yagen, Bailer)

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H315Causes skin irritation

Precautionary statements

P262Do not get in eyes, on skin, or on clothing.

P280Wear protective gloves/protective clothing/eye protection/face protection.

Less

N-Bromosuccinimide Price

Cayman Chemical

Product number: 11444
Product name: T-2 Toxin
Purity: ≥98%
Packaging: 1mg
Price: $57
Updated: 2024/03/01

Cayman Chemical

Product number: 11444
Product name: T-2 Toxin
Purity: ≥98%
Packaging: 5mg
Price: $208
Updated: 2024/03/01

Usbiological

Product number: 021217
Product name: T-2 Toxin
Packaging: 1mg
Price: $263
Updated: 2021/12/16

Biosynth Carbosynth

Product number: BT162749
Product name: T2 Toxin
Packaging: 5mg
Price: $295
Updated: 2021/12/16

AK Scientific

Product number: 9088AJ
Product name: T-2Toxin
Packaging: 5mg
Price: $328
Updated: 2021/12/16

Less

T-2 TOXIN Chemical Properties,Usage,Production

Description

T-2 toxin is a trichothecene mycotoxin that has been found in Fusarium. It binds to and inhibits peptidyltransferase in the 60S ribosomal subunit, inducing a ribotoxic stress response that triggers JNK and p38 MAPK signaling. T-2 toxin (3 nM) decreases toll-like receptor expression and LPS-induced production of IL-1β, TNF-α, and nitric oxide (NO) in, and is cytotoxic to (IC₅₀ = 19.47), primary pig alveolar macrophages (PAMs). In vivo, T-2 toxin induces production of reactive oxygen species (ROS), lipid peroxidation, and glutathione (GSH) depletion in mouse brain and is lethal to mice (LD₅₀s = 1.54-5.94 mg/kg). It also induces hepatocyte apoptosis and dyslipidemias in mice. T-2 toxin has been found in Fusarium-infected wheat, barley, and rice crops both in fields and in storage.

Chemical Properties

White powder

Uses

T-2 Toxin is a tricothecene mycotoxin produced by fungi of the genus Fusarium. T-2 Toxin induces DNA damage and cell death on prolonged administration.

Definition

ChEBI: T-2 toxin is a trichothecene mycotoxin produced by fungi of the genus Fusarium. It is a common contaminant in food and feedstuffs of cereal origin and is known to cause a range of toxic effects in humans and animals. It has a role as a mycotoxin, a cardiotoxic agent, a neurotoxin, an environmental contaminant, an apoptosis inducer, a DNA synthesis inhibitor and a fungal metabolite. It is a trichothecene, an acetate ester and an organic heterotetracyclic compound. It is functionally related to a HT-2 toxin.

General Description

T-2 Toxin is found to be a potent trichothecene mycotoxin produced by the genus fusarium fungi in feedstuffs and cereal grains.

Safety Profile

Poison by ingestion, intramuscular, subcutaneous, intraperitoneal, intracerebral, and intravenous routes. Moderately toxic by inhalation. Experimental teratogenic and reproductive effects. A skin irritant. Questionable carcinogen with experimental neoplastigenic data. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.

T-2 TOXIN Preparation Products And Raw materials

Raw materials

Preparation Products

Less

T-2 TOXIN Suppliers

Australia 1 Canada 2 China 86 France 1 Germany 4 India 2 Japan 1 Norway 1 Switzerland 3 United Kingdom 5 United States 9 Global 115

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32344
Advantage: 50

ShangHai Caerulum Pharma Discovery Co., Ltd.

Tel: 18149758185
Email: sales-cpd@caerulumpharma.com
Country: China
ProdList: 3421
Advantage: 58

ChemStrong Scientific Co.,Ltd

Tel: 0755-0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 17981
Advantage: 56

Shanghai Macklin Biochemical Co.,Ltd.

Tel: 15221275939 15221275939
Fax: 021-50706099
Email: shenlinxing@macklin.cn
Country: China
ProdList: 15878
Advantage: 55

Hangzhou J&H Chemical Co., Ltd.

Tel: +86-571-87396432
Fax: 0571-87396431
Email: sales@jhechem.com
Country: China
ProdList: 10015
Advantage: 53

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51471
Advantage: 80

Alta Scientific Co., Ltd.

Tel: 022-6537-8550 15522853686
Fax: 022-2532-9655
Email: sales@altasci.com.cn
Country: China
ProdList: 4515
Advantage: 55

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9709
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 27322
Advantage: 60

Qingdao IniKem BioPharmaTech Co.,Ltd

Tel: 0532-58268780 18653202088
Fax: -
Email: sales@inikem.com
Country: China
ProdList: 289
Advantage: 55

ShangHai Biochempartner Co.,Ltd

Tel: 17754423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8003
Advantage: 62

Shanghai Rechem science Co., Ltd.

Tel: 21-31433387 15618786686
Fax: QQ:1369748377
Email: sales@rechemscience.com
Country: China
ProdList: 2982
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 12308
Advantage: 58

Anhui kuer Bioengineering Co., Ltd

Tel: 0551-65171243 13810511747
Email: kuer@kuerhuaxue.com
Country: China
ProdList: 2997
Advantage: 55

Chengdu Push Bio-Technology Co., Ltd.

Tel: 028-85370565-229 18080489829
Email: 3004654993@qq.com
Country: China
ProdList: 9176
Advantage: 60

Shanghai Hongye Biotechnology Co. Ltd

Tel: 400-9205774
Email: sales@glpbio.cn
Country: China
ProdList: 6870
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 13028896684
Email: sales@rrkchem.com
Country: China
ProdList: 55827
Advantage: 58

Fan De(Beijing) Biotechnology Co., Ltd.

Tel: 15911056312
Email: liming@bio-fount.com
Country: China
ProdList: 9730
Advantage: 58

TOSUN PHARM

Tel: 020-61855200 13326451905
Email: 2881290884@qq.com
Country: China
ProdList: 7494
Advantage: 58

Hebei Yanxi Chemical Co., Ltd.

Tel: +8617531190177
Email: peter@yan-xi.com
Country: China
ProdList: 5994
Advantage: 58

Hubei Ipure Biology Co., Ltd

Tel: +8613367258412
Fax: 18062427325
Email: ada@ipurechemical.com
Country: China
ProdList: 10326
Advantage: 58

HONG KONG IPURE BIOLOGY CO.,LIMITED

Tel: 86 18062405514 18062405514
Email: ada@ipurechemical.com
Country: CHINA
ProdList: 3465
Advantage: 58

Chengdu Peter-like Biotechnology Co., Ltd.

Tel: 028-81700200 18108052721
Email: 2850505130@qq.com
Country: China
ProdList: 5182
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11289
Advantage: 58

career henan chemical co

Tel: +86-0371-86658258 15093356674;
Fax: 0086-371-86658258
Email: factory@coreychem.com
Country: China
ProdList: 29826
Advantage: 58

ShangHai Anpel Co, Ltd.

Tel: 18501792038; 18501792038
Email: shanpel@anpel.com.cn
Country: China
ProdList: 9614
Advantage: 58

Wuhan lanabai Pharmaceutical Chemical Co., Ltd

Tel: 15307151931
Fax: QQ-2355680
Email: 2355680@qq.com
Country: China
ProdList: 8229
Advantage: 58

Shaanxi Dideu Medichem Co. Ltd

Tel: 029-61856359 18690052321
Fax: 029-88380327
Email: 1027@dideu.com
Country: China
ProdList: 10007
Advantage: 58

Shanghai Hewu Biotechnology Co., LTD

Tel: 021-57886085 17317861055
Email: shhebio@126.com
Country: CHINA
ProdList: 7975
Advantage: 58

Nanjing Shizhou Biology Technology Co.,Ltd

Tel: 025-85560043 13675144456
Fax: 025-85563444
Email: sean.lv@synzest.com
Country: China
ProdList: 11442
Advantage: 58

Wuhan Yanzhe Technology Co., Ltd

Tel: 15527250409
Fax: QQ：2692360204
Email: wenhaotian12@163.com
Country: China
ProdList: 4576
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing@energy-chemical.com
Country: China
ProdList: 44941
Advantage: 58

ChengDu SinoStandards Bio-Tech Co.,Ltd. ，

Tel: 028-83243028 19136088901
Email: sinostandards@163.com
Country: China
ProdList: 5003
Advantage: 58

Wuhan Topule

Tel: +86-02787215551 +86-19945035818
Fax: 027-87215551
Email: 2936752263@qq.com
Country: China
ProdList: 7954
Advantage: 58

TCI (Shanghai) Chemical Trading Co., Ltd.

Tel: 021-61109150
Fax: 021-61105897
Email: sales@tcisct.com
Country: China
ProdList: 31163
Advantage: 58

Changzhou Xianglong Pharmaceutical Technology Co., LTD

Tel: 18661161657
Email: yaoxiangqiu2021@163.com
Country: China
ProdList: 10066
Advantage: 58

Hubei Kele Fine Chemical Co., Ltd

Tel: 027-59101668 19945030958
Fax: 027-59101668
Email: 2881924765@qq.com
Country: China
ProdList: 7980
Advantage: 58

Wuhan Augda Biotechnology Co., Ltd

Tel: 15071299552
Fax: QQ:262933239
Email: 262933239@qq.com
Country: China
ProdList: 6637
Advantage: 58

Chengdu Push Bio-Technology Co., Ltd.

Tel: 18080489829
Email: 3004654993@qq.com
Country: China
ProdList: 9209
Advantage: 58

Wuhan Lvjing Fenghua Biotechnology Co., Ltd.

Tel: 19972070065
Email: 201746457@qq.com
Country: China
ProdList: 6436
Advantage: 58

Wuhan Yingnuo Pharmaceutical Technology Co., Ltd.

Tel: +86-027-59232304 15387063101
Email: 2881924050@qq.com
Country: China
ProdList: 9953
Advantage: 58

Naturewill Biotechnology Co., Ltd.

Tel: 18113192475 18113192475
Email: 3157321941@qq.com
Country: China
ProdList: 5000
Advantage: 58

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 18621169097
Email: market03@meryer.com
Country: China
ProdList: 27996
Advantage: 58

Hubei Enxing Biotechnology Co., Ltd

Tel: 16621771607
Email: exbio_tech@163.com
Country: China
ProdList: 8358
Advantage: 58

Wuhan Jingkangen Biomedical Technology Co., Ltd

Tel: 13720134139 13720134139
Email: orders@jknbiochem.com
Country: China
ProdList: 4958
Advantage: 58

Shanghai Beiwanta Biotechnology Co., Ltd.

Tel: 021-67187366 19901745723
Email: info@bwtlab.com
Country: China
ProdList: 9245
Advantage: 58

Guangzhou Yaoguang Technology Co., Ltd.

Tel: 13020159086
Email: yangjue@ygfuture.com
Country: China
ProdList: 485
Advantage: 58

Shanghai Aladdin Biochemical Technology Co.,Ltd.

Tel: +86-18521732826
Email: market@aladdin-e.com
Country: China
ProdList: 48569
Advantage: 58

Shanghai jerryxing Biomedical Technology Co., Ltd

Tel: 17721492509
Email: 643638326@qq.com
Country: China
ProdList: 5347
Advantage: 58

Less

View Lastest Price from T-2 TOXIN manufacturers

Hebei Yanxi Chemical Co., Ltd.

Product: T-2 TOXIN 21259-20-1
Price: US $50.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 10000
Release date: 2023-09-08

Career Henan Chemical Co

Product: T-2 TOXIN 21259-20-1
Price: US $3.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1kg,5kg,50kg
Release date: 2020-01-18

21259-20-1, T-2 TOXINRelated Search:

Toxin HT 2,T-2, Toxin analog toxin,bluegreenalga,microcystisaeruginos 4-Methyl-2-(2-methyl-1-propenyl)tetrahydropyran (cis- and trans- mixture) TRANS-1,4-CYCLOHEXENEDIOL T-2 TOXIN DIACETOXYSCIRPENOL f-2toxi NEOSOLANIOL deacetyl-ht-2toxi scirpentriol T-2 TETRAOL VERRUCAROL gb2toxi entero-toxin(staphylococcusreduced PERTUSSIS TOXIN BRP DIPHTHERIA TOXIN BRP - * BIOTOX 1KTX SCORPION TOXIN SHK TOXIN

4β,15-Diacetoxy-8α-(3-Methylbutyryloxy)- 12,13-epoxytrichothec-9-en-3α-ol

8α-(3-Methylbutyryloxy)-4β,15- diacetoxyscirp-9-en-3α-ol

T-2 LienoMycin

T-2 Toxin, froM FusariuM tricinctuM

T-2 Toxin, 99%, from Fusarium tricinctum

12,13-epoxytrichothec-9-ene-3-alpha,4-beta,8-alpha,15-tetrol4,15-diacetate8

12,13-trichothecene

3alpha-Hydroxy-4beta,15-diacetoxy-8alpha(3-methylbutyryloxy)-12,13-epoxy-trichothec-9-ene

3alpha-hydroxy-4beta-15-diacetoxy-8alpha-(3-methylbutyryloxy)-12,13-epoxy-delt

3-hydroxy-4,15-diacetoxy-8-(3-methylbutyryloxy)-12,13-epoxy-delta(sup9)-tric

3-hydroxy-4,15-diacetoxy-8-(3-methylbutyryloxy)-12,13-epoxy-delta-(sup9)-trich

3-hydroxy-4,15-diacetoxy-8-[3-methylbutyryloxy]-12,13-epoxytrichothec-9-ene

4,15-diacetoxy-8-(3-methylbutyryloxy)-12,13-epoxy-delta-9-trichothecen-3-ol

4,15-diacetoxy-8-(3-methylbutyryloxy)-12,13-epoxy-delta-9-trichothecen-3-ol[qr

4,15-diacetoxy-8-(3-methylbutyryloxy)scirp-9-en-3-ol

4-beta,15-diacetoxy-8-alpha-(3-methylbutyryloxy)-3-alpha-hydroxy-12,13-epoxy

4beta,8alpha,15-tetrol,12,13-epoxy-,4,15-diacetate8-trichothec-9-ene-3alph

8-(3-methylbutyryloxy)-diacetoxy-scirpeno

8-(3-Methylbutyryloxy)diacetoxyscirpenol

8-(3-methylbutyryloxy)-diacetoxyscirpenol

8-(3-methylbutyryloxy)-diacetoxyscirpenol[qr]

8alpha-(3-methylbutyryloxy)-4beta,15-diacetoxyscirp-9-en-3alpha-ol[qr]

8-isovalerate

a9-tricothecene[qr]

alerate[qr]

fusariotoxinet2

fusariotoxinet2[qr]

t(sub2)-trichothecene[qr]

t-2mycotoxin

t-2mycotoxin[qr]

t2-trichothecene[qr]

Toxin T 2

toxint2

trichothec-9-ene

Trichothec-9-ene-3,4,8,15-tetrol, 12,13-epoxy-, 4,15-diacetate 8-(3-methylbutanoate), (3alpha,4beta,8alpha)-

8alpha-(3-Methylbutyryloxy)-4beta,15-diacetoxyscirp-9-en-3alpha-ol

T2 Toxin / Fusariotoxin T 2 / Insariotoxin / Mycotoxin T 2

T-2 Toxin (T-2 Mycotoxin)

hothecene

Insariotoxin

insariotoxin[qr]

isaritoxin[qr]

-isovalerate

nsc138780

nsc138780[qr]

othecene[qr]

Scirpenol, 8-(3-methylbutyryloxy)-diacetoxy-

trichothec-9-ene-3,4,8,15-tetrol,12,13-epoxy-,4,15-diacetate8-(3-methylbutan

Trichothec-9-ene-3alpha,4beta,8alpha,15-tetrol, 12,13-epoxy-, 4,15-diacetate 8-isovalerate

trichothec-9-ene-3-alpha,4-beta,8-alpha,15-tetrol,12,13-epoxy-,4,15-diacetate

MYCOTOXIN TRICHOTHECENE 2

MYCOTOXIN T 2

T-2 TOXIN

(3-ALPHA, 4-BETA, 8-ALPHA)-TRICHOTHEC-9-ENE-3,4,8,15-TETROL,12,13-EPOXY-, 4,15-DIACETATE 8-(3-METHYLBUTANOATE)

4BETA,15-DIACETOXY-3ALPHA-HYDROXY-8ALPHA-[3-METHYLBUTYRYLOXY]-12,13-EPOXYTRICHOTHEC-9-ENE

100 ug/ml T-2 Toxin in ACN

FUSARIOTOXIN

FUSARIOTOXIN T 2