CALNEXIN ANTIBODY
Source Reactivity Background References- Product Name
- CALNEXIN ANTIBODY
- Chemical Name
- CALNEXIN ANTIBODY
- Synonyms
- CALNEXIN ANTIBODY
- CBNumber
- CB64720632
- Formula Weight
- 0
- MOL File
- Mol file
N-Bromosuccinimide Price
- Product number
- orb10428
- Product name
- Calnexin antibody
- Purity
- Affinity purified by Protein A
- Packaging
- 100μg
- Price
- $421.6
- Updated
- 2021/12/16
- Product number
- orb10428
- Product name
- Calnexin antibody
- Purity
- Affinity purified by Protein A
- Packaging
- 200μg
- Price
- $673.2
- Updated
- 2021/12/16
CALNEXIN ANTIBODY Chemical Properties,Usage,Production
Source
Rabbit
Reactivity
Human
Background
Secretory and transmembrane proteins are synthesized on polysomes and translocate into the endoplasmic reticulum where they are often modified by the formation of disulfide bonds, amino-linked glycosylation and folding. To help proteins fold properly, the ER contains a pool of molecular chaperones including calnexin. Calnexin was first identified as being involved in the assembly of murine class I histocompatibility molecules. Calnexin is a calcium-binding protein embedded in the ER membrane that retains the newly synthesized glycoproteins inside the ER to ensure proper folding and quality control. The specificity of calnexin for a subset of glycoproteins is defined by a lectin site, which binds an early oligosaccharide intermediate on the folding glycoprotein.
References
[1] Degen, E. and Williams, D.B. (1991) J. Cell Biol. 112, 1099-1115.
[2] Ahluwalia, N. et al. (1992) J. Biol. Chem. 267, 10914-10918.
[3] Rajagopalan, S. et al. (1994) Science 263, 387-390.
[4] Bergeron, J.J. et al. (1994) Trends Biochem. Sci. 19, 124-128.
[5] Williams, D.B. (2006) J. Cell Sci. 119, 615-623.
CALNEXIN ANTIBODY Preparation Products And Raw materials
Raw materials
Preparation Products
CALNEXIN ANTIBODY Suppliers
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