GS 143

Product Name: GS 143
CAS No.: 916232-21-8
Chemical Name: GS 143
Synonyms: GS 143;4-(3-Benzyl-4-{[5-(2-fluorophenyl)furan-2-yl]methylidene}-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid;4-[4-[[5-(2-Fluorophenyl)-2-furanyl]methylene]-4,5-dihydro-5-oxo-3-(phenylmethyl)-1H-pyrazol-1-yl]benzoic acid;Benzoic acid, 4-[4-[[5-(2-fluorophenyl)-2-furanyl]methylene]-4,5-dihydro-5-oxo-3-(phenylmethyl)-1H-pyrazol-1-yl]-;E2 conjugating enzyme,inhibit,IκBα,Th2,Ubiquitin conjugating enzyme,GS143,Ubiquitin ligase,IL-4,IκB kinase,βTrCP1,Nuclear factor-kappaB,eosinophil,Ubiquitin activating enzyme,Nuclear factor-κB,I kappa B kinase,NF-κB,E3 ligating enzyme,IKK,E1 activating enzyme,anti-asthma,E1/E2/E3 Enzyme,ubiquitination,Inhibitor,airway,inflammation
CBNumber: CB64721604
Molecular Formula: C28H19FN2O4
Formula Weight: 466.46
MOL File: 916232-21-8.mol

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GS 143 Property

Boiling point:: 667.9±65.0 °C(Predicted)
Density: 1.30±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMF:25.0(Max Conc. mg/mL);53.59(Max Conc. mM)
DMF:PBS (pH 7.2) (1:4):0.2(Max Conc. mg/mL);0.43(Max Conc. mM)
DMSO:31.38(Max Conc. mg/mL);67.28(Max Conc. mM)
form: A crystalline solid
pka: 4.20±0.10(Predicted)
color: Pink to red

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 26138
Product name: GS-143
Packaging: 5mg
Price: $106
Updated: 2024/03/01

Cayman Chemical

Product number: 26138
Product name: GS-143
Packaging: 50mg
Price: $672
Updated: 2024/03/01

Cayman Chemical

Product number: 26138
Product name: GS-143
Packaging: 10mg
Price: $167
Updated: 2024/03/01

Cayman Chemical

Product number: 26138
Product name: GS-143
Packaging: 25mg
Price: $388
Updated: 2024/03/01

Tocris

Product number: 5636
Product name: GS143
Purity: ≥98%(HPLC)
Packaging: 10
Price: $182
Updated: 2021/12/16

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GS 143 Chemical Properties,Usage,Production

Uses

4-[4-[[5-(2-Fluorophenyl)-2-furanyl]methylene]-4,5-dihydro-5-oxo-3-(phenylmethyl)-1H-pyrazol-1-yl]-benzoic Acid blocks LPS-induced expression of inflammatory cytokines in human myelomonocytic cells.

storage

Store at +4°C

GS 143 Preparation Products And Raw materials

Raw materials

Preparation Products

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GS 143 Suppliers

China 20 Japan 1 United Kingdom 1 United States 5 USA 1 Global 28

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4512
Advantage: 55

Struchem Co., Ltd.

Tel: 0512-0512-63009836 15365350169
Fax: 0512-63006936
Email: helen@struchem.com
Country: China
ProdList: 3984
Advantage: 60

Shanghai Chaolan Chemical Technology Center

Tel: 021-QQ：65489617 15618227136
Fax: 21-5161 9052
Email: Sales@ATKchemical.com
Country: China
ProdList: 7269
Advantage: 58

Shanghai Hongye Biotechnology Co. Ltd

Tel: 400-9205774
Email: sales@glpbio.cn
Country: China
ProdList: 6777
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32165
Advantage: 58

DC Chemicals

Tel: 021-58447131 13564518121
Email: sales@dcchemicals.com
Country: China
ProdList: 9409
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11217
Advantage: 58

Jingmo (Xiamen) Biotechnology Co., Ltd

Tel: 13621943973
Email: sales@jamxmpharmatech.com
Country: China
ProdList: 1110
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Jinan Jiuli Biotechnology Co. , Ltd.

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Country: China
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Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 15801484223;
Email: psaitong@jm-bio.com
Country: China
ProdList: 29774
Advantage: 58

916232-21-8, GS 143Related Search:

GS-441524 GS-4361

GS 143

4-[4-[[5-(2-Fluorophenyl)-2-furanyl]methylene]-4,5-dihydro-5-oxo-3-(phenylmethyl)-1H-pyrazol-1-yl]benzoic acid

4-(3-Benzyl-4-{[5-(2-fluorophenyl)furan-2-yl]methylidene}-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid

E2 conjugating enzyme,inhibit,IκBα,Th2,Ubiquitin conjugating enzyme,GS143,Ubiquitin ligase,IL-4,IκB kinase,βTrCP1,Nuclear factor-kappaB,eosinophil,Ubiquitin activating enzyme,Nuclear factor-κB,I kappa B kinase,NF-κB,E3 ligating enzyme,IKK,E1 activating enzyme,anti-asthma,E1/E2/E3 Enzyme,ubiquitination,Inhibitor,airway,inflammation

Benzoic acid, 4-[4-[[5-(2-fluorophenyl)-2-furanyl]methylene]-4,5-dihydro-5-oxo-3-(phenylmethyl)-1H-pyrazol-1-yl]-

916232-21-8