ChemicalBook > CAS DataBase List > 2-CHLORO-3-HYDROXY-4-METHOXYBENZALDEHYDE

2-CHLORO-3-HYDROXY-4-METHOXYBENZALDEHYDE

Product Name: 2-CHLORO-3-HYDROXY-4-METHOXYBENZALDEHYDE
CAS No.: 37687-57-3
Chemical Name: 2-CHLORO-3-HYDROXY-4-METHOXYBENZALDEHYDE
Synonyms: AKOS B028960;chloroisovanilin;Chloroisovaniline;2-CHLOROISOVANILLIN;TIMTEC-BB SBB003704;2-CHLORO-3-HYDROXY-P-ANISALDEHYDE;a-Bromo-5'-fluoro-3'-methoxyacetophenone;2-CHLORO-3-HYDROXY-4-METHOXYBENZALDEHYDE;Benzaldehyde, 2-chloro-3-hydroxy-4-methoxy-;2-Chloro-3-hydroxy-4-methoxybenzaldehyde 97%
CBNumber: CB6472548
Molecular Formula: C8H7ClO3
Formula Weight: 186.59
MOL File: 37687-57-3.mol

Less

2-CHLORO-3-HYDROXY-4-METHOXYBENZALDEHYDE Property

Melting point:: 204-208 °C(lit.)
Boiling point:: 291.3±35.0 °C(Predicted)
Density: 1.377±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
form: solid
pka: 7.77±0.15(Predicted)
Appearance: White to off-white Solid

Less

Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
HS Code: 2913000090

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 565997
Product name: 2-Chloro-3-hydroxy-4-methoxybenzaldehyde
Purity: 97%
Packaging: 5g
Price: $197
Updated: 2023/06/20

TRC

Product number: C585850
Product name: 2-Chloro-3-hydroxy-4-methoxybenzaldehyde
Packaging: 500mg
Price: $75
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC30101
Product name: 2-Chloro-3-hydroxy-4-methoxybenzaldehyde
Packaging: 1g
Price: $52.5
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC30101
Product name: 2-Chloro-3-hydroxy-4-methoxybenzaldehyde
Packaging: 2g
Price: $84
Updated: 2021/12/16

Apolloscientific

Product number: OR929791
Product name: 2-Chloro-3-hydroxy-4-methoxybenzaldehyde
Purity: 95%
Packaging: 1g
Price: $124
Updated: 2021/12/16

Less

2-CHLORO-3-HYDROXY-4-METHOXYBENZALDEHYDE Chemical Properties,Usage,Production

Uses

Reactant for:

BODIPY fluorescent sensors

Synthesis

621-59-0

37687-57-3

Step 1 Synthesis of 2-chloro-3-hydroxy-4-methoxybenzaldehyde: 41.2 g (0.271 mol) of isovanillin was dissolved in 160 mL of 90% acetic acid under heating conditions. 29.41 g of tert-butyl hypochlorite (t-BuOCl) was added slowly and dropwise to the above solution at 35°C to 40°C. The reaction mixture was stirred at room temperature. The reaction mixture was stirred at room temperature for 3 hours, followed by the addition of 200 mL of ether. The mixture was allowed to stand overnight and the precipitated crystals were separated by filtration and washed with ether. The crude product (42.0 g) was purified by recrystallization from acetonitrile to give 35 g of 2-chloro-3-hydroxy-4-methoxybenzaldehyde in 69% yield. The melting point of the product was 203-205 °C. NMR hydrogen spectrum (90 MHz, DMSO-d6) δ: 3.94 (3H, s, OCH3), 7.10 (1H, d, Ar-H), 7.42 (1H, d, Ar-H), 9.84 (1H, s, CHO), 10.16 (1H, s, OH).

References

[1] Journal of Medicinal Chemistry, 1986, vol. 29, # 11, p. 2315 - 2325
[2] Organic Process Research and Development, 2001, vol. 5, # 1, p. 45 - 49
[3] Synlett, 2014, vol. 25, # 20, p. 2891 - 2894
[4] Journal of Organic Chemistry, 2012, vol. 77, # 2, p. 977 - 984
[5] Journal of Heterocyclic Chemistry, 1986, vol. 23, # 6, p. 1805 - 1814

2-CHLORO-3-HYDROXY-4-METHOXYBENZALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

Less

2-CHLORO-3-HYDROXY-4-METHOXYBENZALDEHYDE Suppliers

Belgium 1 China 74 Germany 1 India 1 Japan 1 Switzerland 1 United Kingdom 4 United States 12 Global 95

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Hangzhou Minsuo Technology Co., Ltd.

Tel: 571-88199336 18957129209
Fax: 0571-88190523
Email: 309645123@qq.com
Country: China
ProdList: 53
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Nanjing Norris-Pharm Technology Co., Ltd

Tel: 18652989687
Fax: +86-25-52131256
Email: sales@norris-pharm.com
Country: China
ProdList: 8878
Advantage: 55

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-6206333 13167063860
Fax: 021-50323701
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

Cantotech Chemicals, Ltd.

Tel: 86-0755-86635001
Fax: 86-0755-22642228
Email: cantotech@126.com
Country: China
ProdList: 4566
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Wuxi Zhongkun Biochemical Technology Co., Ltd.

Tel: 0510-85629785 18013409632
Fax: 051085625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 15178
Advantage: 58

Shanghai ChuangYan Chemical Technology Co., Ltd.

Tel: 021-11111111 11111111111
Fax: qq:546919421
Email: 546919421@qq.com
Country: China
ProdList: 3526
Advantage: 55

Tianjin Anhao Biological Technology Co., Ltd.

Tel
Email: sales@ahpharmatech.com
Country: China
ProdList: 5734
Advantage: 55

Changzhou Tianrui Pharmaceutical Technology Co., Ltd.

Tel: 0519-85386832 13382812559
Fax: 0519-85386832
Email: sales@cztrchem.com
Country: China
ProdList: 1185
Advantage: 56

Cool Pharm, Ltd

Tel: 021-60455363 18019463053
Fax: 50966098
Email: sales@coolpharm.com
Country: China
ProdList: 12346
Advantage: 58

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51395
Advantage: 80

Changzhou Anxuan Chemical, Co., Ltd.

Tel: 13912302692 13912302692;
Fax: 0519-88064678
Email: sales@anxuanchem.com
Country: China
ProdList: 4828
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Chengdu Huachun Technology Co., Ltd

Tel: 400-1166-196 15982826727
Fax: QQ：800101999
Email: cdhxsj@163.com
Country: China
ProdList: 14603
Advantage: 60

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Zhengzhou Huiju Chemical Co., Ltd.

Tel: 0371-55900031 18137872243
Fax: QQ：2853979815
Email: 2853979815@qq.com
Country: China
ProdList: 9984
Advantage: 55

Shanghai CR Corporation Limited

Tel: 13062833949; 4006653949 4006653949
Fax: QQ: 2136646215
Email: fred.wen@crcorporation.cn
Country: China
ProdList: 9754
Advantage: 58

Shanghai Zhen Li Biological Technology Co., Ltd

Tel: 021-16621358918; 18516310516
Fax: 13045646768
Email: zhenlipharma888@163.com
Country: China
ProdList: 19035
Advantage: 58

Hubei XinMingTai Chemical Co., Ltd.

Tel: 177-7179-1433 17771741533
Fax: 027-62437337
Email: 1228159977@qq.com
Country: China
ProdList: 1298
Advantage: 58

Capot Chemical Co.,Ltd.

Tel: +86-（0）57185586718; +8613336195806
Fax: +86-571-85864795
Email: sales@capot.com
Country: China
ProdList: 29735
Advantage: 60

Aikon International Limited

Tel: 025-66061636 18013972705
Fax: (3)02557626880
Email: qqyang@aikonchem.com
Country: China
ProdList: 15814
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 400821072
Fax: 021-58955996
Email: malulu@leyan.com
Country: China
ProdList: 25000
Advantage: 58

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400-6387771-6039 18920764717
Email: sales@heowns.com
Country: China
ProdList: 23771
Advantage: 60

Wuhu Nuowei Chemical Technology Co., Ltd

Tel: 553-553-2911116-803-803 18055326116
Email: sales@nuowei-chem.com
Country: China
ProdList: 305
Advantage: 58

CR Corporation Limited

Tel: +8613062833949
Email: fred.wen@crcorporation.cn
Country: China
ProdList: 8645
Advantage: 58

Hefei TNJ Chemical Industry Co.,Ltd.

Tel: +86-0551-65418671 +8618949823763
Fax: 0551-65418697
Email: sales@tnjchem.com
Country: China
ProdList: 34563
Advantage: 58

CD Chemical Group Limited

Tel: +8615986615575
Fax: 0086-13651442114
Email: info@codchem.com
Country: China
ProdList: 20342
Advantage: 58

Win-Win chemical CO., Limited

Tel: +86-0086-577-64498589 +86-15355981851
Fax: 0086-577-56994596
Email: sales@win-winchemical.com
Country: China
ProdList: 14359
Advantage: 58

Jinan Qinmu Fine Chemical Co.,Ltd.

Tel: +8618660799346
Fax: +86 531 8316 6650
Email: sales@qinmuchem.com
Country: China
ProdList: 1008
Advantage: 58

Amel Pharmatech Corporation

Tel: 027-888-4366503
Fax: 888-502-1736
Email: sales@amelpharmatech.com
Country: China
ProdList: 5000
Advantage: 58

Shanghai Amico Chemicals Co. LTD

Tel: 微信 17321281695 18019252918
Fax: qq:1454668768
Email: 1454668768@qq.com
Country: China
ProdList: 14873
Advantage: 58

CONIER CHEM AND PHARMA LIMITED

Tel: +8618523575427
Email: sales@conier.com
Country: China
ProdList: 49975
Advantage: 58

career henan chemical co

Tel: +86-0371-86658258 +8613203830695
Fax: 0086-371-86658258
Email: factory@coreychem.com
Country: China
ProdList: 29798
Advantage: 58

Fuxin Pharmaceutical

Tel: +86-021-021-50872116 +8613122107989
Email: contact@fuxinpharm.com
Country: China
ProdList: 10000
Advantage: 58

Suzhou Ningrui Pharmaceutical Co., Ltd

Tel: 0512-18261440723
Email: 2149720772@qq.com
Country: China
ProdList: 51
Advantage: 58

Chongqing Kemai Material Technology Co., Ltd

Tel: 17830741407
Fax: QQ：2479150351
Email: sales@chem47.com
Country: China
ProdList: 1768
Advantage: 58

Lingyuan Bebiansen Biological Technology Co., Ltd

Tel: 18642120371
Email: 2837458851@qq.com
Country: China
ProdList: 7963
Advantage: 58

Nanjing Puxin Pharmaceutical Technology Co., Ltd

Tel: 17366295326
Fax: QQ360829978
Email: puxinpharma_2017@126.com
Country: China
ProdList: 2444
Advantage: 58

Shanghai Sunway Pharmaceutical Technology Co.,Ltd.

Tel: 021-51816796-820 13611835272
Fax: 021-5161 3951
Email: sales2@sunwaypharm.com
Country: China
ProdList: 44119
Advantage: 58

Hebei Zhentian Food Additives Co., Ltd.

Tel: 0551-77777777-5 13333333333
Fax: 0319 5925599
Country: China
ProdList: 9998
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-6005915
Email: sales@picasso-e.com
Country: China
ProdList: 39653
Advantage: 58

Jiaxing Zhejia Biotechnology Co., LTD

Tel: 0573-85609002 18367600069;
Email: zhejia01@163.com
Country: China
ProdList: 8887
Advantage: 58

Changzhou Wanyao Biotechnology Co., Ltd.

Tel: 051989185693 15312551983
Email: 2410037592@qq.com
Country: China
ProdList: 1201
Advantage: 58

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 17801761073
Email: Gsiyu@solarbio.com
Country: China
ProdList: 50464
Advantage: 58

Zhuhai Aobokai Biomedical Technology Co., Ltd.

Tel: 400-0628126 15697567703
Email: sales-team@aobchem.com.cn
Country: China
ProdList: 49999
Advantage: 58

Changzhou Yanji Biotechnology Co., Ltd.

Tel: 0519-83556355 18015005120
Fax: -
Email: shikewei397@163.com
Country: China
ProdList: 3734
Advantage: 55

Hefei Mokai Pharmaceutical Technology Co., Ltd

Tel: 19355912709
Email: 690231469@qq.com
Country: China
ProdList: 7593
Advantage: 58

Nanjing Shizhou Biology Technology Co.,Ltd

Tel: 025-85560043 15850508050
Fax: 025-85563444
Email: rose.shi@synzest.com
Country: China
ProdList: 6210
Advantage: 58

Less

View Lastest Price from 2-CHLORO-3-HYDROXY-4-METHOXYBENZALDEHYDE manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: 2-Chloro-3-Hydroxy-4-Methoxybenzaldehyde 37687-57-3
Price: US $65.00-20.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20ton
Release date: 2024-06-04

Capot Chemical Co.,Ltd.

Product: 2-Chloro-3-hydroxy-4-methoxybenzaldehyde 37687-57-3
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: kgs
Release date: 2023-01-03

Career Henan Chemical Co

Product: 2-CHLORO-3-HYDROXY-4-METHOXYBENZALDEHYDE 37687-57-3
Price: US $6.60/KG
Min. Order: 1KG
Purity: 97%-99%
Supply Ability: 1kg -1000kg
Release date: 2020-01-02

37687-57-3, 2-CHLORO-3-HYDROXY-4-METHOXYBENZALDEHYDERelated Search:

2-Chloroveratraldehyde Quincarbate 5-CHLORO-4-HYDROXY-3-METHOXYBENZALDEHYDE,3-CHLORO-4-HYDROXY-5-METHOXYBENZALDEHYDE 2-CHLORO-3,4-DIMETHOXYBENZOIC ACID 2-CHLORO-3,4-DIMETHOXYBENZAMIDE 2-CHLORO-3-HYDROXY-4-METHOXYBENZOIC ACID METHYL 2-CHLORO-3,4-DIMETHOXYBENZOATE 2-CHLORO-3,4-DIMETHOXY-6-NITROBENZALDEHYDE ETHYL 2-CHLORO-3,4-DIMETHOXYBENZOATE 2-CHLORO-3-HYDROXY-4-METHOXYBENZALDEHYDE 2-BROMO-3-CHLORO-4-HYDROXY-5-METHOXYBENZALDEHYDE 2,6-DICHLORO-3,4-DIMETHOXYBENZALDEHYDE 2-CHLORO 3,4 DIMETHOXY BENZIL RARECHEM AL BF 0917 RARECHEM AL BE 0997 RARECHEM AL BI 0907 RARECHEM AL BI 0997 RARECHEM AL BE 0917

2-CHLOROISOVANILLIN

2-CHLORO-3-HYDROXY-4-METHOXYBENZALDEHYDE

2-CHLORO-3-HYDROXY-P-ANISALDEHYDE

2-Chloro-3-hydroxy-p-anisaldehyde, 2-Chloroisovanillin

Chloroisovaniline

2-Chloro-3-hydroxy-4-methoxybenzaldehyde 97%

TIMTEC-BB SBB003704

AKOS B028960

Benzaldehyde, 2-chloro-3-hydroxy-4-methoxy-

chloroisovanilin

a-Bromo-5'-fluoro-3'-methoxyacetophenone

37687-57-3

7687-57-3

CH3OC6H2ClOHCHO

C8H7CIO3

Organic Building Blocks

Building Blocks

Aldehydes

Carbonyl Compounds