ChemicalBook > CAS DataBase List > MA-0204

MA-0204

Product Name
MA-0204
CAS No.
2095128-17-7
Chemical Name
MA-0204
Synonyms
CS-2841;MA-0204;MA-0204, 10 mM in DMSO;MA0204,inhibit,MA 0204,Peroxisome proliferator-activated receptors,MA-0204,PPAR,Inhibitor;(R)-3-methyl-6-(2-((5-methyl-2-(4-(trifluoromethoxy)phenyl)-1H-imidazol-1-yl)methyl)phenoxy)hexanoic acid;(3R)-3-methyl-6-[2-({5-methyl-2-[4-(trifluoromethoxy)phenyl]-1H-imidazol-1-yl}methyl)phenoxy]hexanoic acid;Hexanoic acid, 3-methyl-6-[2-[[5-methyl-2-[4-(trifluoromethoxy)phenyl]-1H-imidazol-1-yl]methyl]phenoxy]-, (3R)-
CBNumber
CB64744843
Molecular Formula
C25H27F3N2O4
Formula Weight
476.49
MOL File
2095128-17-7.mol
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MA-0204 Property

Boiling point:
611.9±65.0 °C(Predicted)
Density 
1.23±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
form 
Solid
pka
4.76±0.10(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0064227
Product name
MA-0204
Purity
99.71%
Packaging
5mg
Price
$450
Updated
2021/12/16
ChemScene
Product number
CS-0064227
Product name
MA-0204
Purity
99.71%
Packaging
10mg
Price
$750
Updated
2021/12/16
Biorbyt Ltd
Product number
orb573177
Product name
MA-0204
Purity
>98%
Packaging
100mg
Price
$1431.4
Updated
2021/12/16
ChemScene
Product number
CS-0064227
Product name
MA-0204
Purity
99.71%
Packaging
25mg
Price
$1500
Updated
2021/12/16
ChemScene
Product number
CS-0064227
Product name
MA-0204
Purity
99.71%
Packaging
50mg
Price
$2100
Updated
2021/12/16
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MA-0204 Chemical Properties,Usage,Production

Uses

MA-0204 is a potent, highly selective and orally available peroxisome proliferator activated receptor δ (PPARδ) modulator with EC50s of 0.4 nM, 7.9 nM and 10 nM for human, mouse and rat PPARδ, respectively. Potential treatment for Duchene Muscular Dystrophy (DMD)[1].

in vivo

PPARδ (30, 100 mg/kg) increases target gene transcription in the muscle[1].

IC 50

PPARδ: 0.4 nM (EC50, in human); PPARδ: 7.9 nM (EC50, in mouse); PPARδ: 10 nM (EC50, in rat)

References

[1] Lagu B, et al. Selective PPARδ Modulators Improve Mitochondrial Function: Potential Treatment for Duchenne Muscular Dystrophy (DMD). ACS Med Chem Lett. 2018 Jul 31;9(9):935-940. DOI:10.1021/acsmedchemlett.8b00287

MA-0204 Preparation Products And Raw materials

Raw materials

Preparation Products

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MA-0204 Suppliers

China 36 United States 3 Global 39
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
15883
Advantage
64
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696，15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4757
Advantage
55
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
ShangHai Biochempartner Co.,Ltd
Tel
177-54423994 17754423994
Fax
QQ:2853530913
Email
2853530910@QQ.com
Country
China
ProdList
8000
Advantage
62
Shanghai Chaolan Chemical Technology Center
Tel
021-QQ：65489617 15618227136
Fax
21-5161 9052
Email
Sales@ATKchemical.com
Country
China
ProdList
9125
Advantage
58
Fujian boshi pharmaceutical technology co. LTD
Tel
0595-22008920; 18120708884
Email
393612455@qq.com
Country
China
ProdList
255
Advantage
58
Fan De(Beijing) Biotechnology Co., Ltd.
Tel
15911056312
Email
liming@bio-fount.com
Country
China
ProdList
9729
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6391
Advantage
58

2095128-17-7, MA-0204Related Search:


  • MA-0204
  • CS-2841
  • Hexanoic acid, 3-methyl-6-[2-[[5-methyl-2-[4-(trifluoromethoxy)phenyl]-1H-imidazol-1-yl]methyl]phenoxy]-, (3R)-
  • MA0204,inhibit,MA 0204,Peroxisome proliferator-activated receptors,MA-0204,PPAR,Inhibitor
  • (R)-3-methyl-6-(2-((5-methyl-2-(4-(trifluoromethoxy)phenyl)-1H-imidazol-1-yl)methyl)phenoxy)hexanoic acid
  • (3R)-3-methyl-6-[2-({5-methyl-2-[4-(trifluoromethoxy)phenyl]-1H-imidazol-1-yl}methyl)phenoxy]hexanoic acid
  • MA-0204, 10 mM in DMSO
  • 2095128-17-7