ChemicalBook > CAS DataBase List > AC-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER-OH

AC-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER-OH

Product Name
AC-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER-OH
CAS No.
66641-26-7
Chemical Name
AC-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER-OH
Synonyms
Ac-Angiotensinogen (1-14), porcine;Angiotensinogenn-acetyl-fragment1-14;ACETYL-ANGIOTENSINOGEN (1-14) (HORSE);ACETYL ANGIOTENSINOGEN (1-14), PORCINE;ACETYL-PREANGIOTENSINOGEN (1-14) (HORSE);ACETYL-TETRADECAPEPTIDE RENIN SUBSTRATE (HORSE);N-ACETYL-RENIN SUBSTRATE TETRADECAPEPTIDE PORCINE;AC-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER;AC-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER-OH;ACETYL-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER
CBNumber
CB6477149
Molecular Formula
C87H125N21O21
Formula Weight
1801.05
MOL File
66641-26-7.mol
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AC-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER-OH Property

Density 
1.41±0.1 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
insoluble in EtOH; insoluble in H2O; ≥180.1 mg/mL in DMSO
form 
solid
pka
2.98±0.10(Predicted)
Sequence
Ac-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Leu-Val-Tyr-Ser
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ApexBio Technology
Product number
A1034
Product name
Acetyl Angiotensinogen (1-14), porcine
Packaging
5mg
Price
$45
Updated
2021/12/16
Chem-Impex
Product number
32965
Product name
Ac-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Leu-Val-Tyr-Ser-OH
Packaging
1MG
Price
$74.55
Updated
2021/12/16
ApexBio Technology
Product number
A1034
Product name
Acetyl Angiotensinogen (1-14), porcine
Packaging
10mg
Price
$75
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA110828
Product name
Ac-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-Leu-Val-Tyr-Ser-OH
Packaging
1mg
Price
$98
Updated
2021/12/16
ApexBio Technology
Product number
A1034
Product name
Acetyl Angiotensinogen (1-14), porcine
Packaging
25mg
Price
$105
Updated
2021/12/16
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AC-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER-OH Chemical Properties,Usage,Production

Uses

Acetyl angiotensinogen (1-14), porcine is a synthetic peptide and N-terminal acetylated form of Angiotensinogen (1-14) porcine (HY-P4774)[1].

Biological Activity

acetyl angiotensinogen (1-14),porcine, (c87h125n21o21) is a peptide with the sequence ac-asp-arg-val-tyr-ile-his-pro-phe-his-leu-leu-val-tyr-ser-oh, mw= 1801.05. the protein encoded by the angiotensinogen gene is known as pre-angiotensinogen or angiotensinogen precursor. pre-angiotensinogen is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure(1). the resulting product, angiotensin i, is then cleaved by angiotensin converting enzyme (ace) to generate the physiologically active enzyme angiotensin ii. angiotensin ii is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia(2). mutations in the gene are associated with susceptibility to essential hypertension and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. defects in the gene have also been associated with non-familial structural atrial fibrillation and inflammatory bowel disease.figure1 formula of acetyl angiotensinogen (1-14),porcinefigure2 the renin–angiotensin–aldosterone system

References

1. Basso N, Terragno NA (December 2001). "History about the discovery of the renin-angiotensin system". Hypertension 38 (6): 1246–9.2. Skurk T, Lee YM, Hauner H (May 2001). "Angiotensin II and its metabolites stimulate PAI-1 protein release from human adipocytes in primary culture". Hypertension 37 (5): 1336–40.

AC-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from AC-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER-OH manufacturers

Career Henan Chemical Co
Product
AC-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER-OH 66641-26-7
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100kg
Release date
2020-02-18

66641-26-7, AC-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER-OHRelated Search:


  • N-ACETYL-RENIN SUBSTRATE TETRADECAPEPTIDE PORCINE
  • AC-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER
  • AC-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER-OH
  • ACETYL-ANGIOTENSINOGEN (1-14) (HORSE)
  • ACETYL ANGIOTENSINOGEN (1-14), PORCINE
  • ACETYL-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-LEU-LEU-VAL-TYR-SER
  • ACETYL-TETRADECAPEPTIDE RENIN SUBSTRATE (HORSE)
  • ACETYL-PREANGIOTENSINOGEN (1-14) (HORSE)
  • Angiotensinogenn-acetyl-fragment1-14
  • Ac-Angiotensinogen (1-14), porcine
  • Acetyl-Preangiotensinogen (1-14) (horse), Acetyl-Tetradecapeptide Renin Substrate (horse), Acetyl-Angiotensinogen (1-14) (horse)
  • Angiotensinogen (tetradecapeptide renin substrate), N-acetyl-5-L-isoleucine-
  • 66641-26-7
  • C87H125N21O21
  • Biochemicals and Reagents
  • Amino Acids and Peptides
  • BioChemical
  • Peptides
  • Other Peptides
  • SignalTransduction