ORY-1001(trans)

Product Name: ORY-1001(trans)
CAS No.: 1431303-72-8
Chemical Name: ORY-1001(trans)
Synonyms: Ladademstat;ORY-1001(trans);ORY1001 HCl salt;ORY-1001(Ladademstat);ORY-1001 dihydrochloride;Iadademstat dihydrochloride;Iadademstat dihydrochloride, 10 mM in DMSO;(1r,4R)-N1-((1R,2S)-2-phenylcyclopropyl)cyclohexane-1,4-diamine;trans-N1-((1R,2S)-2-Phenylcyclopropyl)cyclohexane-1,4-diamine dihydrochloride;RO 7051790,RG 6016,Iadademstat dihydrochloride,Histone Demethylase,Iadademstat,RO7051790,inhibit,RG6016,Inhibitor,ORY1001,RO-7051790,ORY 1001,ORY-1001,RG-6016
CBNumber: CB64796675
Molecular Formula: C15H23ClN2
Formula Weight: 266.81
MOL File: 1431303-72-8.mol

More

Less

ORY-1001(trans) Property

storage temp.: Store at -20°C
solubility: Water: 57.75 mg/mL (190.42 mM and warming); DMSO: 0.69 mg/mL (2.28 mM and warming)
form: Solid
color: White to off-white

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

ChemScene

Product number: CS-0044434
Product name: ORY-1001(trans)
Purity: 98.30%
Packaging: 5mg
Price: $110
Updated: 2021/12/16

ChemScene

Product number: CS-0044434
Product name: ORY-1001(trans)
Purity: 98.30%
Packaging: 10mg
Price: $180
Updated: 2021/12/16

ChemScene

Product number: CS-0044434
Product name: ORY-1001(trans)
Purity: 98.30%
Packaging: 50mg
Price: $700
Updated: 2021/12/16

ChemScene

Product number: CS-0044434
Product name: ORY-1001(trans)
Purity: 98.30%
Packaging: 100mg
Price: $1200
Updated: 2021/12/16

More

Less

ORY-1001(trans) Chemical Properties,Usage,Production

Uses

Iadademstat (ORY-1001) dihydrochloride is a selective irreversible lysine (K)-specific demethylase 1A (KDM1A/LSD1) inhibitor.

in vivo

Iadademstat reduces AML tumor growth in mice and rat xenografts and increases survival time in a disseminated model of T-ALL^[1].

References

[1] Maes T, et al. KDM1 histone lysine demethylases as targets for treatments of oncological and neurodegenerative disease. Epigenomics. 2015;7(4):609-26. doi: 10.2217/epi.15.9. DOI:10.2217/epi.15.9
[2] Tamara Maes, et al. ORY-1001, a Potent and Selective Covalent KDM1A Inhibitor, for the Treatment of Acute Leukemia. Cancer Cell. 2018 Mar 12;33(3):495-511.e12. DOI:10.1016/j.ccell.2018.02.002

ORY-1001(trans) Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

ORY-1001(trans) Suppliers

China 26 United States 2 Global 28

Sichuan Wei Keqi Biological Technology Co., Ltd.

Tel: 028-81700200 18116577057
Fax: 028-81705658
Email: 3003855609@qq.com
Country: China
ProdList: 7778
Advantage: 56

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9803
Advantage: 58

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 18101056239
Email: 3193328036@qq.com
Country: China
ProdList: 29760
Advantage: 68

Jiaxing Deyi Chemical Co., Ltd.

Tel: 86-0573-85866609 13325730825
Fax: 0573-85866609
Email: 945717149@qq.com
Country: China
ProdList: 8593
Advantage: 58

Fan De(Beijing) Biotechnology Co., Ltd.

Tel: 15911056312
Email: liming@bio-fount.com
Country: China
ProdList: 9729
Advantage: 58

HANGZHOU CLAP TECHNOLOGY CO.,LTD

Tel: 86-571-88216897,88216896 13588875226
Fax: 86-571-88216895
Email: sales@hzclap.com
Country: CHINA
ProdList: 6312
Advantage: 58

Changzhou Chenhong Biotechnology Co., Ltd.

Tel: +86-0519-85788828 +86-13775037613
Email: sales@chemrenpharm.com
Country: China
ProdList: 3934
Advantage: 58

ChemeGen(Shanghai) Biotechnology Co.,Ltd.

Tel: 18818260767
Fax: QQ 3610331285
Email: sales@chemegen.com
Country: China
ProdList: 11218
Advantage: 58

Shanghai hongqu biomedical technology co. LTD

Tel: 88888888888
Email: hongquchem@qq.com
Country: China
ProdList: 5132
Advantage: 58

1431303-72-8, ORY-1001(trans)Related Search:

ORY-1001(trans)

trans-N1-((1R,2S)-2-Phenylcyclopropyl)cyclohexane-1,4-diamine dihydrochloride

Ladademstat

ORY-1001 dihydrochloride

Iadademstat dihydrochloride

RO 7051790,RG 6016,Iadademstat dihydrochloride,Histone Demethylase,Iadademstat,RO7051790,inhibit,RG6016,Inhibitor,ORY1001,RO-7051790,ORY 1001,ORY-1001,RG-6016

(1r,4R)-N1-((1R,2S)-2-phenylcyclopropyl)cyclohexane-1,4-diamine

ORY-1001(Ladademstat)

ORY1001 HCl salt

Iadademstat dihydrochloride, 10 mM in DMSO

1431303-72-8