COX-2 (human) Inhibitor Screening Assay Kit

Product Name: COX-2 (human) Inhibitor Screening Assay Kit
Chemical Name: COX-2 (human) Inhibitor Screening Assay Kit
Synonyms: COX-2 (human) Inhibitor Screening Assay Kit
CBNumber: CB64814449
Formula Weight: 0
MOL File: Mol file

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 701080
Product name: COX-2 (human) Inhibitor Screening Assay Kit
Packaging: 96Well
Price: $436
Updated: 2024/03/01

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COX-2 (human) Inhibitor Screening Assay Kit Chemical Properties,Usage,Production

Description

COX-1 and COX-2 catalyze the production of the prostaglandin (PG) and thromboxane precursor PGH₂. COX-2 is primarily responsible for the biosynthesis of PGs under acute inflammatory conditions. The COX-2 (human recombinant) Inhibitor Screening Assay measures PGF_2α that is produced by SnCl₂ reduction of COX-2-derived PGH₂. PGF_2α is quantified via enzyme immunoassay (EIA) using a broadly specific antiserum that binds to all the major PG compounds. This assay includes human recombinant COX-2 and is an excellent tool which can be used for general inhibitor screening, or to eliminate false positive leads generated by less specific methods.

References

[1] LINLIN XIE . Characterization of spirostanol glycosides and furostanol glycosides from anemarrhenae rhizoma as dual targeted inhibitors of 5-lipoxygenase and Cyclooxygenase-2 by employing a combination of affinity ultrafiltration and HPLC/MS[J]. Phytomedicine, 2020, 77: Article 153284. DOI: 10.1016/j.phymed.2020.153284
[2] MOSAAD S MOHAMED. Molecular modelling insights into a physiologically favourable approach to eicosanoid biosynthesis inhibition through novel thieno[2,3-b]pyridine derivatives.[J]. Journal of Enzyme Inhibition and Medicinal Chemistry, 2018, 33 1: 755-767. DOI: 10.1080/14756366.2018.1457657

COX-2 (human) Inhibitor Screening Assay Kit Preparation Products And Raw materials

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COX-2 (human) Inhibitor Screening Assay Kit Suppliers

CHINA 3 United States 1 Global 4

amyjet

Tel: 4006800868;027-59626688 18371453821;18771149750
Email: sales@amyjet.com
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Cayman Chemical Company

Tel: 800-364-9897
Email: sales@caymanchem.com
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Langfang Yusheng Ruichuang Technology Co., Ltd.

Tel: 17398520978
Country: CHINA
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COX-2 (human) Inhibitor Screening Assay Kit