MLN-4760

Product Name: MLN-4760
CAS No.: 305335-31-3
Chemical Name: MLN-4760
Synonyms: MLN-4760;((S)-1-carboxy-2-(1-(3,5-dichlorobenzyl)-1H-imidazol-5-yl)ethyl)-L-leucine;L-Histidine, N-[(1S)-1-carboxy-3-methylbutyl]-3-[(3,5-dichlorophenyl)methyl]-;inhibit,Angiotensin-converting Enzyme (ACE),MLN 4760,Inhibitor,MLN-4760,MLN4760;(2S)-2-{[(1S)-1-carboxy-2-{1-[(3,5-dichlorophenyl)methyl]-1H-imidazol-5-yl}ethyl]amino}-4-methylpentanoic acid
CBNumber: CB64845021
Molecular Formula: C19H23Cl2N3O4
Formula Weight: 428.31
MOL File: 305335-31-3.mol

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MLN-4760 Property

storage temp.: Store at -20°C
solubility: DMSO: soluble
form: A solid
color: Off-white to light yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H332Harmful if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P330Rinse mouth.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 5.30616
Product name: ACE2 Inhibitor, MLN-4760
Purity: ≥97% (HPLC), powder, Calbiochem?
Packaging: 2MG
Price: $273
Updated: 2023/01/07

ChemScene

Product number: CS-0015513
Product name: MLN-4760
Purity: 99.93%
Packaging: 1mg
Price: $200
Updated: 2021/12/16

ChemScene

Product number: CS-0015513
Product name: MLN-4760
Purity: 99.93%
Packaging: 5mg
Price: $480
Updated: 2021/12/16

ChemScene

Product number: CS-0015513
Product name: MLN-4760
Purity: 99.93%
Packaging: 10mg
Price: $800
Updated: 2021/12/16

ChemScene

Product number: CS-0015513
Product name: MLN-4760
Purity: 99.93%
Packaging: 25mg
Price: $1700
Updated: 2021/12/16

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MLN-4760 Chemical Properties,Usage,Production

Definition

ChEBI: MLN-4760 is a L-histidine derivative that is L-histidine in which a hydrogen of the primary amino group is substituted by a (1S)-1-carboxy-3-methylbutyl group and the ring NH group is substituted by a 3,5-dichlorobenzyl group. It is a potent and selective human angiotensin-converting enzyme 2 (ACE2) inhibitor (IC50 = 0.44 nM) which was in clinical development for the treatment of ulcerative colitis. It has a role as an anti-inflammatory agent and an EC 3.4.17.23 (angiotensin-converting enzyme 2) inhibitor. It is a L-histidine derivative, a dichlorobenzene and a L-leucine derivative.

storage

Store at -20°C

MLN-4760 Preparation Products And Raw materials

Raw materials

Preparation Products

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MLN-4760 Suppliers

China 29 United States 5 Global 34

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305335-31-3, MLN-4760Related Search:

Pevonedistat MLN9708 MLN-8237

MLN-4760

L-Histidine, N-[(1S)-1-carboxy-3-methylbutyl]-3-[(3,5-dichlorophenyl)methyl]-

((S)-1-carboxy-2-(1-(3,5-dichlorobenzyl)-1H-imidazol-5-yl)ethyl)-L-leucine

inhibit,Angiotensin-converting Enzyme (ACE),MLN 4760,Inhibitor,MLN-4760,MLN4760

(2S)-2-{[(1S)-1-carboxy-2-{1-[(3,5-dichlorophenyl)methyl]-1H-imidazol-5-yl}ethyl]amino}-4-methylpentanoic acid

305335-31-3