ChemicalBook > CAS DataBase List > H-Lys(Boc)-OH

H-Lys(Boc)-OH

Product Name
H-Lys(Boc)-OH
CAS No.
2418-95-3
Chemical Name
H-Lys(Boc)-OH
Synonyms
H-LYS(BOC)-OH;LYS(BOC);Lys(Boc)-OH;N6-Boc-L-lysine;(S)-2-AMino-6-((tert-butoxycarbonyl)aMino)hexanoic acid;L-LYS(BOC);Nepsilon L;L-LYSINE(BOC);LYSINE(BOC)-OH;e-BOC-L-lysine.
CBNumber
CB6485395
Molecular Formula
C11H22N2O4
Formula Weight
246.3
MOL File
2418-95-3.mol
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H-Lys(Boc)-OH Property

Melting point:
250 °C (dec.)(lit.)
alpha 
17 º (c=1% in acetic acid)
Boiling point:
389.3°C (rough estimate)
Density 
1.1313 (rough estimate)
refractive index 
18 ° (C=1, AcOH)
storage temp. 
2-8°C
solubility 
Soluble in DMSO
form 
powder to crystal
pka
2.53±0.24(Predicted)
color 
White to Almost white
optical activity
[α]20/D +18°, c = 1 in acetic acid
Water Solubility 
Slightly soluble in water.
BRN 
2417626
InChIKey
VVQIIIAZJXTLRE-QMMMGPOBSA-N
CAS DataBase Reference
2418-95-3(CAS DataBase Reference)
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Safety

Safety Statements 
24/25
WGK Germany 
3
HS Code 
29241990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
359661
Product name
H-Lys(Boc)-OH
Purity
≥95%
Packaging
5g
Price
$627
Updated
2025/07/31
TCI Chemical
Product number
B1670
Product name
Nepsilon-(tert-Butoxycarbonyl)-L-lysine
Purity
>97.0%(T)
Packaging
1g
Price
$71
Updated
2025/07/31
TCI Chemical
Product number
B1670
Product name
Nepsilon-(tert-Butoxycarbonyl)-L-lysine
Purity
>97.0%(T)
Packaging
5g
Price
$201
Updated
2025/07/31
TRC
Product number
B656905
Product name
Nε-Boc-L-lysine
Packaging
1g
Price
$50
Updated
2021/12/16
TRC
Product number
B656905
Product name
Nε-Boc-L-lysine
Packaging
100g
Price
$970
Updated
2021/12/16
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H-Lys(Boc)-OH Chemical Properties,Usage,Production

Chemical Properties

white crystalline powder

Uses

It is used as therapy to treat recurrent herpes simplex infections.

General Description

H-Lys(Boc)-OH, also known as H-Lys(t-BOC)-OH, is an ε-amino-protected lysine. Its e-amino free lysine could be conjugated to polyurethane surfaces by reaction of the alpha-amino group with the NHS and deprotection. The covalent conjugation was carried out in phosphate-buffered saline (PBS), pH 8.2. Lysine was used to create a plasminogen-binding potentially fibrinolytic surface[1].

References

[1] Chen H , et al. Surfaces having dual fibrinolytic and protein resistant properties by immobilization of lysine on polyurethane through a PEG spacer. Journal of Biomedical Materials Research Part A, 2008; 90A: 940-946.

reaction suitability

reaction type: solution phase peptide synthesis

Synthesis

71989-26-9

2418-95-3

Step 1. N-alpha-Fluorenylmethoxycarbonyl-N-epsilon-tert-butoxycarbonyl-L-lysine (5 g, 10.7 mmol) was dissolved in dichloromethane (DCM) at room temperature and piperidine (5.5 ml, 53 mmol) was added with stirring. The reaction mixture was stirred continuously for 16 hours at room temperature. Upon completion of the reaction, the reaction mixture was extracted with water, the aqueous phase was combined and concentrated to afford N(e)-Boc-L-lysine (20-3) in 95% yield.

H-Lys(Boc)-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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H-Lys(Boc)-OH Suppliers

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View Lastest Price from H-Lys(Boc)-OH manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd
Product
H-Lys(Boc)-OH 2418-95-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1T+
Release date
2023-09-27
Chengdu Baishixing Science and Technology Industry Co.,Ltd
Product
Ne-Boc-L-lysine 2418-95-3
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2T/month
Release date
2023-07-26
Sichuan Jiaying Lai Technology Co.,LTD
Product
Lys(Boc) 2418-95-3
Price
US $1.00/g
Min. Order
1g
Purity
98%
Supply Ability
100KG
Release date
2019-07-29

2418-95-3, H-Lys(Boc)-OHRelated Search:

N-Carbobenzyloxyglycine Boc-Aib-OH Fmoc-N'-methyltrityl-L-lysine L-Lysine tert-Butyl carbazate Poly(L-lysine hydrobromide) Poly-L-lysine 5-Hydroxytryptophan (S)-2-amino-3-(4-(2-tert-butoxy-2-oxoethyl)phenyl)propanoic acid H-LYS(ALLOC)-OH N-EPSILON-ACETYL-L-LYSINE H-Lys(Boc)-OBzl·HCl Biocytin H-L-Pen-OH.HCl.H2O BOC-GLY-LEU-OH L-Phenylalanine, 4-cyclohexyl- H-L-Lys-NEt2.2HCl H-L-Tyr-NEt2.HCl

  • Lys(Boc)-OH
  • (S)-2-AMino-6-((tert-butoxycarbonyl)aMino)hexanoic acid
  • L-Lysine,N<sup>6</sup>-[(1,1-diMethylethoxy)carbonyl]-
  • H-Lys(Boc)-OH >=95%
  • Nε-Boc-L-Lysine≥ 98% (HPLC)
  • Ne-Boc-L-lysine N<sub>ε</sub>-Boc-L-lysine N-epsilon-tert-Butoxycarbonyl-L-lysine
  • Nepsilon-Boc-L-lysine H-Lys(Boc)-OH
  • N6-Boc-L-lysine
  • N-EPSILON-(TERT-BUTOXYCARBONYL)-L-LYSINE 97%
  • N-epsilon-Boc-L-lysine,99%
  • e-BOC-L-lysine.
  • L-LYS(BOC)
  • N-EPSILON-T-BUTYLOXYCARBONYL-L-LYSINE
  • Ne-Boc-L-lysine
  • BOC-L-LYSINE extrapure
  • Nepsilon-BOC-L-Lysine,97%
  • (2S)-2-Amino-6-(tert-butoxycarbonylamino)hexanoic acid
  • epsilon-tert-butyloxycarbonyl-lysine
  • L-LYSINE(BOC)
  • LYSINE(BOC)-OH
  • LYS(BOC)
  • H-LYS(BOC)-OH
  • H-L-LYS(BOC)-OH
  • N-ALPHA-T-BOC-L-LYS
  • N-EPSILON-(TERT-BUTOXYCARBONYL)-L-LYSINE
  • N-EPSILON-TERT-BUTYLOXYCARBONYL-L-LYSINE
  • NEPSILON-BOC-L-LYSINE
  • N-EPSILON-T-BUTOXYCARBONYL-L-LYSINE
  • N-EPSILON-T-BOC-L-LYSINE
  • Nepsilon L
  • L-Lysine, N6-[(1,1-dimethylethoxy)carbonyl]-
  • Ne-Boc-L-lysine USP/EP/BP
  • (2S)-2-azaniumyl-6-[(2-methylpropan-2-yl)oxycarbonylamino]hexanoate
  • H-Lys(Boc)-OH 98%
  • 2418-95-3
  • 2418-95-1
  • 418-95-3
  • CH33COCONHCH24CHNH2COOH
  • Specialty Synthesis
  • Amino Acid Derivatives
  • Lysine
  • Peptide Synthesis
  • Boc-Amino Acids
  • Protected & Labeled Amino Acids
  • Amino Acids (N-Protected)
  • Lysine [Lys, K]
  • Amino Acids and Derivatives
  • Amino Acids (N-Protected)
  • Biochemistry
  • Boc-Amino Acids
  • Boc-Amino acid series
  • Amino Acids