4,7-Dichloroquinoline

ChemicalBook > CAS DataBase List > 4,7-Dichloroquinoline

4,7-Dichloroquinoline

Product Name: 4,7-Dichloroquinoline
CAS No.: 86-98-6
Chemical Name: 4,7-Dichloroquinoline
Synonyms: COPPER SEBACATE;Sulfate Impurity;4,7-dichloro-quinolin;tl1473;TL 1473;4, 7-dichloroquine;7-Dichloroquinoline;Chloroquine USP RC A;Amobiquine Impurity 1;4,7-DICHLOROQUINOLINE
CBNumber: CB6490818
Molecular Formula: C9H5Cl2N
Formula Weight: 198.05
MOL File: 86-98-6.mol

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4,7-Dichloroquinoline Property

Melting point:: 81-83 °C (lit.)
Boiling point:: 298.4 °F (148°C)
Density: 1.4178 (rough estimate)
vapor pressure: 0.103Pa at 25℃
refractive index: 1.6300 (estimate)
Flash point:: 164 °C
storage temp.: 2-30°C
solubility: chloroform: soluble50mg/mL, clear, colorless to greenish-yellow
pka: 1.99±0.27(Predicted)
form: Powder
color: White to pale brown
Water Solubility: insoluble
BRN: 125359
InChIKey: HXEWMTXDBOQQKO-UHFFFAOYSA-N
LogP: 3.193 at 25℃
CAS DataBase Reference: 86-98-6(CAS DataBase Reference)
NIST Chemistry Reference: Quinoline, 4,7-dichloro-(86-98-6)
EPA Substance Registry System: 4,7-Dichloroquinoline (86-98-6)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36-22
WGK Germany: 3
RTECS: VB4200000
Hazard Note: Irritant
TSCA: Yes
HS Code: 29334910

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H317May cause an allergic skin reaction

H319Causes serious eye irritation

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHR2438
Product name: Chloroquine Related Compound A
Purity: Pharmaceutical Secondary Standard; Certified Reference Material
Packaging: 50MG
Price: $668
Updated: 2024/03/01

Sigma-Aldrich

Product number: 141437
Product name: 4,7-Dichloroquinoline
Purity: ≥99%
Packaging: 25g
Price: $117
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1118328
Product name: Chloroquine Related Compound A
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 15MG
Price: $1210
Updated: 2024/03/01

Sigma-Aldrich

Product number: 1118328
Product name: Chloroquine Related Compound A
Purity: United States Pharmacopeia (USP) Reference Standard
Packaging: 25mg
Price: $1220
Updated: 2022/05/15

TCI Chemical

Product number: D1100
Product name: 4,7-Dichloroquinoline
Purity: >98.0%(GC)
Packaging: 25g
Price: $42
Updated: 2024/03/01

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4,7-Dichloroquinoline Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powder

Uses

4,7-Dichloroquinoline is used in the synthesis of hybrid aminoquinoline-triazine derivatives that show anti-microbial activity. In addition, it is used in the synthesis of novel oxazolidinones as anti -microbial agents showing efficacy against common bacterial strains. Chloroquinoline impurity.

Uses

4,7-Dichloroquinoline is used as a drug chloroquine phosphate intermediate. It was used in the synthesis of piperaquine. and as starting reagent in the synthesis of {3-amino-5-[(7-chloro-4-quinolyl)amino]phenyl}methanol.

General Description

Chloroquine Related Compound A is an impurity of chloroquine, which is a 9-aminoquinoline drug that effectively inhibits viral infections in humans.

Flammability and Explosibility

Not classified

Synthesis

4,7-Dichloroquinoline is obtained by chlorination of 7-chloro-4-hydroxyquinoline.

Purification Methods

Crystallise the dichloroquinoline from MeOH or 95% EtOH. [Beilstein 20/7 V 316.]

4,7-Dichloroquinoline Preparation Products And Raw materials

Raw materials

7-Chloroquinolin-4-ol

Preparation Products

7-Chloro-4-piperazinoquinoline 4-BROMO-7-CHLOROQUINOLINE CHLOROQUINE

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View Lastest Price from 4,7-Dichloroquinoline manufacturers

Jinan Finer Chemical Co., Ltd

Product: 4,7-Dichloroquinoline 86-98-6
Price: US $0.00/Kg/Drum
Min. Order: 1g
Purity: 99%
Supply Ability: 20mt
Release date: 2020-03-31

Shaanxi Dideu Medichem Co. Ltd

Product: 4,7-Dichloroquinoline 86-98-6
Price: US $0.00-0.00/KG
Min. Order: 1g
Purity: 99%
Supply Ability: 2000tons
Release date: 2019-12-31

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 4,7-Dichloroquinoline 86-98-6
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99% GC
Supply Ability: 500kgs
Release date: 2023-05-15

86-98-6, 4,7-DichloroquinolineRelated Search:

1,2-Dichloro-4-(chloromethyl)benzene 2,4-Dichlorophenol CHLOROQUINE Isoquinoline 3，7-Dichloroquinoline acid-8,3,7-DICHLOROQUINOLINE-8-CARBOXYLIC ACID 2',4'-Dichloroacetophenone 2,4-Dichlorobenzoic acid 7,10-dichloro-2-methoxybenzo[b]-1,5-naphthyridine 4,7-DICHLORO-2,8-DIMETHYLQUINOLINE 2-METHYL-4,5,7-TRICHLOROQUINOLINE 4,7-DICHLORO-2-METHYLQUINOLINE 2-METHYL-4,7,8-TRICHLOROQUINOLINE 6,9-Dichloro-2-methoxyacridine 6,7-Dichloroquinoline 2,8-DICHLOROQUINOLINE 5,7-Dichloroquinoline Pigment Red 202 4,8-DICHLOROQUINOLINE

Hydroxychloroquine Sulfate Impurity 7（Hydroxychloroquine Sulfate EP Impurity G）

Hydroxychloroquine Sulfate EP Impurity G

Sulfate Impurity

4,7-DICHLOROQUINOLINE

4,7-dichloro-quinolin

TL 1473

tl1473

Amobiquine Impurity 1

COPPER SEBACATE

4,7-Dichloroquinoline,97%

4,7-DICHLOLROQUINOLINE

4,7-DICHLOROQUINOLINE CHLOROQUINE PHOSPHATE

7-Dichloroquinoline

Chloroquine Related Compound A (25 mg) (4,7-dichloroquinoline)

4,7-Dichloroquinoline,98%

4,7-Dichloroquinoline,95%,tech.

Quinoline, 4,7-dichloro-

4,7-Dichloro-1-azanaphthalene

Chloroquine Related CoMpound A

4,7-DICHLOROQUINOLINE, 99+%

4,7-Dichloroquinoline(For Quinoline)

Hydroxychloroquine sulfate Impurity 4

Amodiaquine Impurity 1 (Hydroxychloroquine Sulfate EP Impurity G)

4,7-Dichloroquinoline&gt

Chloroquine USP RC A

N4-(7-chloroquinolin-4-yl)-N1-ethylpentane-1,4-diamine sulfate

Amodiaquine Dichloro Impurity (Hydroxychloroquine EP Impurity G/ Chloroquine?Related Compound A)

4,7-DICHLOROQUINOLINE 86-98-6

Chloroquine?Related Compound A (Amodiaquine Dichloro Impurity/ Hydroxychloroquine EP Impurity G)

Hydroxychloroquine EP Impurity G (Amodiaquine Dichloro Impurity)

High quailty 4,7-Dichloroquinoline 86-98-6

4,7- DichloroquinolineQ: What is 4,7- Dichloroquinoline Q: What is the CAS Number of 4,7- Dichloroquinoline Q: What is the storage condition of 4,7- Dichloroquinoline

Chloroquine Related Compound A (4,7-dichloroquinoline) (1118328)

4, 7-dichloroquine

Chloroquine USP Related Compound A

Lead hydroxide oxide sulfate 11083-39-9

4,7-dichloroquinoline (4,7-DCQ)

4,7-Dichloroquinolone

Hydroxychloroquine Sulfate Impurity G

Hydroxychloroquine EP Impurity G 4,7-Dichlrorquinoline

86-98-6

7640-85-7

C9H5Cl2N

Halogenated Heterocycles

Heterocyclic Building Blocks

Haloquinolines

Quinolines

Building Blocks

C8 to C10

Chemical Synthesis

Halogenated Heterocycles

Heterocyclic Building Blocks

Haloquinolines

Building Blocks

Halogenated Heterocycles

Heterocyclic Building Blocks

QuinolinesHeterocyclic Building Blocks