ChemicalBook > CAS DataBase List > A-METHYL-DL-P-TYROSINE

A-METHYL-DL-P-TYROSINE

Product Name
A-METHYL-DL-P-TYROSINE
CAS No.
658-48-0
Chemical Name
A-METHYL-DL-P-TYROSINE
Synonyms
h9/88;MK-781;Valine-d1;rac metyrosine D3;DL-α-Methyltyrosine;α-Methyl-p-tyrosine;alpha-methyl-tyrosin;α-Methylparatyrosine;A-METHYL-DL-P-TYROSI;α-Methyl-DL-tyrosine
CBNumber
CB6498278
Molecular Formula
C10H13NO3
Formula Weight
195.22
MOL File
658-48-0.mol
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A-METHYL-DL-P-TYROSINE Property

Melting point:
>300 °C(lit.)
Boiling point:
331.88°C (rough estimate)
Density 
1.1926 (rough estimate)
refractive index 
1.5150 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Aqueous Acid (Sparingly), Aqueous Base, Water (Slightly)
form 
Solid
pka
2.29±0.16(Predicted)
color 
White to Off-White
BRN 
2938704
InChI
InChI=1S/C10H13NO3/c1-10(11,9(13)14)6-7-2-4-8(12)5-3-7/h2-5,12H,6,11H2,1H3,(H,13,14)
InChIKey
NHTGHBARYWONDQ-UHFFFAOYSA-N
SMILES
C(O)(=O)C(C)(CC1C=CC(O)=CC=1)N
EPA Substance Registry System
.alpha.-Methyltyrosine (658-48-0)
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
RTECS 
YP2890000
HS Code 
29225000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
120693
Product name
α-Methyl-DL-tyrosine
Purity
98%
Packaging
5g
Price
$170
Updated
2023/01/07
Sigma-Aldrich
Product number
120693
Product name
α-Methyl-DL-tyrosine
Purity
98%
Packaging
25g
Price
$675
Updated
2023/01/07
TRC
Product number
M332685
Product name
α-Methyl-D,L-tyrosine
Packaging
2.5g
Price
$180
Updated
2021/12/16
Activate Scientific
Product number
AS48401
Product name
2-Amino-3-(4-hydroxyphenyl)-2-methylpropanoic acid
Purity
97%
Packaging
5G
Price
$207
Updated
2021/12/16
Ark Pharm
Product number
AK129847
Product name
2-Amino-3-(4-hydroxyphenyl)-2-methylpropanoicacid
Purity
97%
Packaging
250mg
Price
$14
Updated
2021/12/16
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A-METHYL-DL-P-TYROSINE Chemical Properties,Usage,Production

Chemical Properties

off-white fine powder

Uses

peptide synthesis

reaction suitability

reaction type: solution phase peptide synthesis

in vivo

α-Methyl-p-tyrosine (250 mg/kg, intraperitoneal injection, single dose) can exacerbate the severity and duration of tonic and clonic seizures induced by Pentylenetetrazol in male CFI mice[2].

Animal Model:Pentylenetetrazol (PTZ)-induced epilepsy CFI strain mouse model (15-25 g)
Dosage:250 mg/kg
Administration:Intraperitoneal injection (i.p.), single dose, PTZ administered 8 hours after α-Methyl-p-tyrosine injection?
Result:Increased the severity and duration of seizures, especially enhancing tonic and clonic seizures induced by PTZ.

A-METHYL-DL-P-TYROSINE Preparation Products And Raw materials

Raw materials

Preparation Products

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A-METHYL-DL-P-TYROSINE Suppliers

Belgium 1 Canada 1 China 89 Europe 1 France 1 Germany 2 India 3 Switzerland 2 United Kingdom 2 United States 15 Global 117
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View Lastest Price from A-METHYL-DL-P-TYROSINE manufacturers

Career Henan Chemical Co
Product
A-METHYL-DL-P-TYROSINE 658-48-0
Price
US $1.00/g
Min. Order
1g
Purity
99.0%
Supply Ability
100kg
Release date
2020-01-09

658-48-0, A-METHYL-DL-P-TYROSINERelated Search:

racephedrine DL-Tyrosine ALPHA-METHYL-DL-P-TYROSINE METHYL ESTER HYDROCHLORIDE N-ACETYL-O-METHYL-DL-ORTHO-TYROSINE ETHYL ESTER Α-METHYL-DL-M-TYROSINE α-Methyl-DL-p-tyrosine,ALPHA-METHYL-DL-P-TYROSINE ALPHA-METHYL-DL-M-TYROSINE METHYL ESTER HYDROCHLORIDE: MONOHYDRATE N-ACETYL-O-METHYL-DL-ORTHO-TYROSINE ETHYL ESTER Α-METHYL-DL-P-TYROSINE METHYL ESTER Α-METHYL-DL-M-TYROSINE METHYL ESTER Fmoc-a-methyl-DL-m-tyrosine N-ACETYL-O-METHYL-DL-META-TYROSINE ETHYL ESTER

  • (2R)-2-ammonio-3-(4-hydroxyphenyl)-2-methylpropanoate
  • A-METHYL-DL-P-TYROSINE
  • alpha-methyl-para-tyrosine
  • alpha-methyl-p-tyrosine
  • alpha-methyl-tyrosin
  • h9/88
  • DL-α-Methyltyrosine
  • 2-P-HYDROXYPHENYLMETHYL-DL-ALANINE
  • Tyrosine, .alpha.-methyl-
  • DL-2-METHYL-4-TYROSINE
  • 2-Amino-3-(4-hydroxy-phenyl)-2-methyl-propionic acid
  • DL-2-Methyl-3-(4-hydroxyphenyl)alanine, AMPT
  • 2-Amino-3-(4-hydroxyphenyl)-2-methylpropanoic acid
  • MK-781
  • α-Amino-β-(4-hydroxyphenyl)-α-methylpropionic acid
  • α-Methylparatyrosine
  • α-Methyl-p-tyrosine
  • DL-alpha-Methyltyrosine,98%
  • DL-alpha-Methyltyrosinealpha-MT
  • DL-alpha-Methyltyrosine
  • A-METHYL-DL-P-TYROSI
  • (S)-2-AMino-3-(4-hydroxyphenyl)-2-Methylpropanoic acid
  • (S-2-Amino-3-(4-Hydroxyphenyl-2-Methylpro
  • α-Methyl-DL-tyrosine
  • (S)-2-Amino-3-(4-hydroxyphenyl)-2-methylpropanoicaci
  • A-METHYL-DL-P-TYROSINE USP/EP/BP
  • rac metyrosine D3
  • inhibit,DOPA,catecholamine synthesis,tyrosine hydroxylase,Inhibitor,Racemetirosine
  • Valine-d1
  • METHYL-DL-TYROSINE, ALPHA-
  • α-Methyl-<sc>DL</sc>-tyrosine
  • Racemetyrosine (SM-88)
  • 658-48-0
  • 658-48-1
  • 4HOC6H4CH2CCH3NH2CO2H