4 4'-DIISOTHIOCYANATO-2 2'-STILBENEDISU&
- Product Name
- 4 4'-DIISOTHIOCYANATO-2 2'-STILBENEDISU&
- CAS No.
- 207233-90-7
- Chemical Name
- 4 4'-DIISOTHIOCYANATO-2 2'-STILBENEDISU&
- Synonyms
- 4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-D;4 4'-DIISOTHIOCYANATO-2 2'-STILBENEDISU&;Disodium 4,4′-diisothiocyanatostilbene-2,2′-disulfonate;DIDS, Disodium 4,4μ-diisothiocyanatostilbene-2,2μ-disulfonate;Disodium 4,4'-diisothiocyanato-2,2'-stilbenedisulphonate hydrate;4,4''-DIISOTHIOCYANATOSTILBENE-2,2''-DISULPHONIC ACID DISODIUM SALT;disodium 2,2'-(E)-ethene-1,2-diylbis(5-isothiocyanatobenzenesulfonate);4,4'-diisothiocyanatostilbene-2,2'-disulfonic acid disodium salt hydrate;4,4'-Diisothiocyanatostilbene-2,2'-disulfonic acid disodium salt hydrate;4,4'-Diisothiocyanatostilbene-2,2'-disulphonic acid disodium salt hydrate
- CBNumber
- CB6499068
- Molecular Formula
- C16H13N2NaO7S4
- Formula Weight
- 496.52
- MOL File
- 207233-90-7.mol
4 4'-DIISOTHIOCYANATO-2 2'-STILBENEDISU& Property
- storage temp.
- 2-8°C
- solubility
- 0.1 M potassium bicarbonate: soluble50mg/mL
- form
- powder
- color
- yellow
- BRN
- 8179433
Safety
- Hazard Codes
- Xn
- Risk Statements
- 36/37/38-42
- Safety Statements
- 22-26
- WGK Germany
- 3
- HS Code
- 29309090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H334May cause allergy or asthma symptoms or breathing difficulties if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- D3514
- Product name
- 4,4′-Diisothiocyanatostilbene-2,2′-disulfonic acid disodium salt hydrate
- Purity
- ≥80% (elemental analysis), powder
- Packaging
- 25mg
- Price
- $60
- Updated
- 2023/01/07
- Product number
- D3514
- Product name
- 4,4′-Diisothiocyanatostilbene-2,2′-disulfonic acid disodium salt hydrate
- Purity
- ≥80% (elemental analysis), powder
- Packaging
- 1g
- Price
- $529
- Updated
- 2022/05/15
- Product number
- D3514
- Product name
- 4,4′-Diisothiocyanatostilbene-2,2′-disulfonic acid disodium salt hydrate
- Purity
- ≥80% (elemental analysis), powder
- Packaging
- 100mg
- Price
- $128
- Updated
- 2023/01/07
- Product number
- D3514
- Product name
- 4,4′-Diisothiocyanatostilbene-2,2′-disulfonic acid disodium salt hydrate
- Purity
- ≥80% (elemental analysis), powder
- Packaging
- 250mg
- Price
- $187
- Updated
- 2022/05/15
- Product number
- BID2117
- Product name
- Disodium4,4'-diisothiocyanato-2,2'-stilbenedisulphonatehydrate
- Packaging
- 100mg
- Price
- $80
- Updated
- 2021/12/16
4 4'-DIISOTHIOCYANATO-2 2'-STILBENEDISU& Chemical Properties,Usage,Production
Uses
4,4′-Diisothiocyanatostilbene-2,2′-disulfonic acid disodium salt hydrate has been used:
- as band3 protein inhibitor in rabbits(19)
- for the inhibition of bicarbonate transporters in brain slice tissue(20)
- as HCO3-/Cl- exchanger (anion exchanger) in embryos(21)
Biochem/physiol Actions
4,4′-Diisothiocyanatostilbene-2,2′-disulfonic acid is an anionic alkylating agent containing isothiocyanate residue. It is a negatively charged homobifunctional cross-linking reagent. 4,4′-Diisothiocyanatostilbene-2,2′-disulfonic acid is a specific inhibitor of cellular anion permeability used in cell transport studies. The isothiocyanate groups react with primary amines at pH 9.0-10.0. 4,4′-Diisothiocyanatostilbene-2,2′-disulfonic acid alkylates lysine residues and inhibits apoptosis indirectly by targeting membrane based anion transporters.In addition, it also inhibits calcium transport in vesicles.
4 4'-DIISOTHIOCYANATO-2 2'-STILBENEDISU& Preparation Products And Raw materials
Raw materials
Preparation Products
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