4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID
- Product Name
- 4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID
- CAS No.
- 53005-05-3
- Chemical Name
- 4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID
- Synonyms
- DIDS, Disodium Salt - CAS 53005-05-3;4,4'-Diisothiocyatostilbene-2,2'-disulfonic acid;4,4'-Diisothiocyano-2,2'-stilbenedisulfonic acid;4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID;4,4'-Diisothiocyanato-2,2'-stilbenedisulfonic acid;4,4'-Bis(isothiocyanato)stilbene-2,2'-bissulfonic acid;4,4'-diisothiocyano-trans-stilbene-2,2'-disulfonic acid;2,2'-(1,2-Ethenediyl)bis(5-isothiocyanatobenzenesulfonic acid);Benzenesulfonic acid,2,2'-(1,2-ethenediyl)bis[5-isothiocyanato-;4,4′-Diisotbiocyano-2,2′-stilbenedisulfnic Acid Disodium Salt
- CBNumber
- CB2683689
- Molecular Formula
- C16H10N2O6S4
- Formula Weight
- 454.52
- MOL File
- 53005-05-3.mol
4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID Property
- Melting point:
- >400°C
- Density
- 1.54±0.1 g/cm3(Predicted)
- pka
- -1.32±0.50(Predicted)
Safety
- HazardClass
- IRRITANT-HARMFUL
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- 309795
- Product name
- DIDS, Disodium Salt - CAS 53005-05-3 - Calbiochem
- Packaging
- 250mg
- Price
- $196
- Updated
- 2024/03/01
- Product number
- CHM0024866
- Product name
- 4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $671.86
- Updated
- 2021/12/16
- Product number
- CHM0024866
- Product name
- 4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $1052.67
- Updated
- 2021/12/16
- Product number
- MT-10026
- Product name
- 4,4'-Diisothiocyanatostilbene-2,2'-disulfonicacid
- Purity
- 98%
- Packaging
- 50g
- Price
- $628
- Updated
- 2021/12/16
4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID Chemical Properties,Usage,Production
Chemical Properties
Yellow Crystalline Solid
Uses
Stilbene disulfonates have been employed to inhibit anion transport in a large number of mammalian cell types (GABA, Cl-). Some stilbene disulfonates can bind specifically to proteins that are not anion transporters. DIDS reacts with CD4 glycoprot
Uses
Ion channel inhibitor; especially of anion transport.
Definition
ChEBI: 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid is an arenesulfonic acid.
General Description
Binds covalently and irreversibly to the outer surface of human erythrocyte membranes. Inhibits ATP transport into endoplasmic reticulum vesicles. Anion transport inhibitor that inhibits Cl– uptake (IC50 = 150 nM) in neuroblastoma cells. Has anti-ulcerous properties.
Biochem/physiol Actions
Primary TargetCl- uptake
4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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