ChemicalBook > CAS DataBase List > 4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID

4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID

Product Name
4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID
CAS No.
53005-05-3
Chemical Name
4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID
Synonyms
DIDS, Disodium Salt - CAS 53005-05-3;4,4'-Diisothiocyatostilbene-2,2'-disulfonic acid;4,4'-Diisothiocyano-2,2'-stilbenedisulfonic acid;4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID;4,4'-Diisothiocyanato-2,2'-stilbenedisulfonic acid;4,4'-Bis(isothiocyanato)stilbene-2,2'-bissulfonic acid;4,4'-diisothiocyano-trans-stilbene-2,2'-disulfonic acid;2,2'-(1,2-Ethenediyl)bis(5-isothiocyanatobenzenesulfonic acid);Benzenesulfonic acid,2,2'-(1,2-ethenediyl)bis[5-isothiocyanato-;4,4′-Diisotbiocyano-2,2′-stilbenedisulfnic Acid Disodium Salt
CBNumber
CB2683689
Molecular Formula
C16H10N2O6S4
Formula Weight
454.52
MOL File
53005-05-3.mol
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4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID Property

Melting point:
>400°C
Density 
1.54±0.1 g/cm3(Predicted)
pka
-1.32±0.50(Predicted)
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Safety

HazardClass 
IRRITANT-HARMFUL
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
309795
Product name
DIDS, Disodium Salt - CAS 53005-05-3 - Calbiochem
Packaging
250mg
Price
$196
Updated
2024/03/01
American Custom Chemicals Corporation
Product number
CHM0024866
Product name
4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID
Purity
95.00%
Packaging
1G
Price
$671.86
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0024866
Product name
4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID
Purity
95.00%
Packaging
5G
Price
$1052.67
Updated
2021/12/16
AHH
Product number
MT-10026
Product name
4,4'-Diisothiocyanatostilbene-2,2'-disulfonicacid
Purity
98%
Packaging
50g
Price
$628
Updated
2021/12/16
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4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID Chemical Properties,Usage,Production

Chemical Properties

Yellow Crystalline Solid

Uses

Stilbene disulfonates have been employed to inhibit anion transport in a large number of mammalian cell types (GABA, Cl-). Some stilbene disulfonates can bind specifically to proteins that are not anion transporters. DIDS reacts with CD4 glycoprot

Uses

Ion channel inhibitor; especially of anion transport.

Definition

ChEBI: 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid is an arenesulfonic acid.

General Description

Binds covalently and irreversibly to the outer surface of human erythrocyte membranes. Inhibits ATP transport into endoplasmic reticulum vesicles. Anion transport inhibitor that inhibits Cl– uptake (IC50 = 150 nM) in neuroblastoma cells. Has anti-ulcerous properties.

Biochem/physiol Actions

Primary TargetCl- uptake

4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID Suppliers

Canada 1 China 15 Germany 2 United Kingdom 5 United States 6 Global 29
Toronto Research Chemicals
Tel
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Fax
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Email
info@trc-canada.com
Country
Canada
ProdList
6038
Advantage
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53005-05-3, 4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACIDRelated Search:

4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID, DISODIUM SALT (DIDS) 4,4'-DIAMINOSTILBENE DIHYDROCHLORIDE 4,4'-DIISOTHIOCYANATO-2,2'-STILBENEDISULFONIC ACID, DISODIUM SALT HYDRATE 4,4'-Diamino-2,2'-stilbenedisulfonic acid 4,4'-diisothiocyanatostilbene-2,2'-disulfonic acid disodium salt hydrate P-VINYLPHENYL ISOTHIOCYANATE 4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID

  • 4,4'-DIISOTHIOCYANATOSTILBENE-2,2'-DISULFONIC ACID
  • 2,2'-(1,2-Ethenediyl)bis(5-isothiocyanatobenzenesulfonic acid)
  • 4,4'-Bis(isothiocyanato)stilbene-2,2'-bissulfonic acid
  • 4,4'-Diisothiocyanato-2,2'-stilbenedisulfonic acid
  • 4,4'-Diisothiocyano-2,2'-stilbenedisulfonic acid
  • 4,4′-Diisotbiocyano-2,2′-stilbenedisulfnic Acid Disodium Salt
  • 5-isothiocyanato-2-[(E)-2-(4-isothiocyanato-2-sulfophenyl)ethenyl]benzenesulfonic acid
  • Benzenesulfonic acid,2,2'-(1,2-ethenediyl)bis[5-isothiocyanato-
  • 4,4'-diisothiocyano-trans-stilbene-2,2'-disulfonic acid
  • 4,4'-Diisothiocyatostilbene-2,2'-disulfonic acid
  • DIDS, Disodium Salt - CAS 53005-05-3
  • 53005-05-3
  • C16H10N2O6S4
  • Cross Linking Reagents
  • Fluorescent Labels & Indicators