3,5-Dibromophenol
- Product Name
- 3,5-Dibromophenol
- CAS No.
- 626-41-5
- Chemical Name
- 3,5-Dibromophenol
- Synonyms
- 3,5-Dlbromophenol;3,5-Dibromophenol;3,5-Dibromophenol>Phenol, 3,5-dibroMo-;3 5-DIBROMOPHENOL 97;3,5-Dibromophenol 98%;Phloroglucinol Impurity 15;3,5-Dibromophenol pure, 98%;3,5-Dibromophenol@100 μg/mL in Toluene
- CBNumber
- CB6500148
- Molecular Formula
- C6H4Br2O
- Formula Weight
- 251.9
- MOL File
- 626-41-5.mol
3,5-Dibromophenol Property
- Melting point:
- 79-83 °C (lit.)
- Boiling point:
- 122°C/3mmHg(lit.)
- Density
- 1.8854 (rough estimate)
- refractive index
- 1.5380 (estimate)
- storage temp.
- Inert atmosphere,Room Temperature
- form
- powder to crystal
- pka
- pK1:8.056 (25°C)
- color
- White to Light yellow to Light orange
- Water Solubility
- Sightly soluble in water. Soluble in methanol.
- InChIKey
- PZFMWYNHJFZBPO-UHFFFAOYSA-N
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 22-36/37/38
- Safety Statements
- 26-36
- RIDADR
- UN 2811 6.1/PG 3
- WGK Germany
- 3
- Hazard Note
- Irritant/Keep Cold
- HazardClass
- 6.1
- PackingGroup
- Ⅲ
- HS Code
- 29081990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 646105
- Product name
- 3,5-Dibromophenol
- Purity
- 97%
- Packaging
- 1g
- Price
- $23.85
- Updated
- 2025/07/31
- Product number
- 646105
- Product name
- 3,5-Dibromophenol
- Purity
- 97%
- Packaging
- 10g
- Price
- $201.5
- Updated
- 2025/07/31
- Product number
- D3820
- Product name
- 3,5-Dibromophenol
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $20
- Updated
- 2025/07/31
- Product number
- D3820
- Product name
- 3,5-Dibromophenol
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $76
- Updated
- 2025/07/31
- Product number
- D425985
- Product name
- 3,5-Dibromophenol
- Packaging
- 10g
- Price
- $155
- Updated
- 2021/12/16
3,5-Dibromophenol Chemical Properties,Usage,Production
Chemical Properties
White to brown solid
Uses
3,5-Dibromophenol is used as a pharmaceutical intermediate. It is also used to prepare aromatic polyesters and drugs for arthritis.
Synthesis
74137-36-3
626-41-5
General procedure for the synthesis of 3,5-dibromophenol from 3,5-dibromoanisole: 3,5-dibromoanisole (15.57 g, 58.5 mmol) and tetrabutylammonium bromide (1.0 g, 3.1 mmol) were suspended in 48% hydrobromic acid solution (100 mL), and heated to reflux for 3 days. After the reaction was completed, it was cooled to room temperature and the reaction mixture was extracted with dichloromethane (3 x 60 mL). The organic layers were combined, washed with water, dried over anhydrous magnesium sulfate and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography (eluent: ethyl acetate/heptane, 10:1, v/v). After removal of the solvent, 14.23 g (97% yield) of 3,5-dibromophenol was obtained as light brown needle-like crystals.
References
[1] Journal of Organic Chemistry, 2004, vol. 69, # 25, p. 8982 - 8983
[2] Patent: US2006/270686, 2006, A1. Location in patent: Page/Page column 35
[3] Journal of Medicinal Chemistry, 2011, vol. 54, # 1, p. 179 - 200
[4] Patent: US2008/280891, 2008, A1. Location in patent: Page/Page column 35
[5] Patent: WO2008/8059, 2008, A1. Location in patent: Page/Page column 96
3,5-Dibromophenol Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3,5-Dibromophenol manufacturers
- Product
- 3,5-Dibromophenol 626-41-5
- Price
- US $34.00-1.20/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-08
- Product
- 3,5-Dibromophenol 626-41-5
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- Customized
- Release date
- 2019-05-23