ATRACTYLINE(DISCONTINUED)(SH)

Product Name: ATRACTYLINE(DISCONTINUED)(SH)
CAS No.: 6989-21-5
Chemical Name: ATRACTYLINE(DISCONTINUED)(SH)
Synonyms: Atractyline;(4aS,8aR)-3,8a-diMethyl-5-Methylene-4,4a,5,6,7,8,8a,9-octahydronaphtho[2,3-b]furan;ATRACTYLINE(DISCONTINUED)(SH);(4aS)-4,4aα,5,6,7,8,8a,9-Octahydro-3,8aβ-dimethyl-5-methylenenaphtho[2,3-b]furan;(4aS,8aR)-4,4a,5,6,7,8,8a,9-Octahydro-3,8a-dimethyl-5-methylene-naphtho[2,3-b]furan;Naphtho[2,3-b]furan, 4,4a,5,6,7,8,8a,9-octahydro-3,8a-diMethyl-5-Methylene-, (4aS,8aR)-
CBNumber: CB6500946
Molecular Formula: C15H20O
Formula Weight: 216.32
MOL File: 6989-21-5.mol

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ATRACTYLINE(DISCONTINUED)(SH) Property

Melting point:: 61-63℃
Boiling point:: 287.1±19.0℃ (760 Torr)
Density: 1.02±0.1 g/cm3 (20 ºC 760 Torr)
Flash point:: 121.7±8.3℃
storage temp.: 2-8°C
solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form: Soild
color: Faint red to very dark red
InChI: InChI=1S/C15H20O/c1-10-5-4-6-15(3)8-14-12(7-13(10)15)11(2)9-16-14/h9,13H,1,4-8H2,2-3H3/t13-,15+/m0/s1
InChIKey: TYPSVDGIQAOBAD-DZGCQCFKSA-N
SMILES: O1C=C(C)C2C[C@]3([H])[C@@](C)(CC1=2)CCCC3=C
LogP: 5.570

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML3510
Product name: Atractylon
Purity: ≥85% (HPLC)
Packaging: 5MG
Price: $87.2
Updated: 2023/06/20

Sigma-Aldrich

Product number: SML3510
Product name: Atractylon
Purity: ≥85% (HPLC)
Packaging: 25MG
Price: $351
Updated: 2023/06/20

Biosynth Carbosynth

Product number: FA74011
Product name: Atractylon
Packaging: 2mg
Price: $50
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA74011
Product name: Atractylon
Packaging: 5mg
Price: $100
Updated: 2021/12/16

AK Scientific

Product number: 6693CJ
Product name: Atractylon
Packaging: 2mg
Price: $117
Updated: 2021/12/16

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ATRACTYLINE(DISCONTINUED)(SH) Chemical Properties,Usage,Production

Chemical Properties

Yellow liquid, soluble in organic solvents such as methanol, ethanol, DMSO, etc., derived from Atractylodes macrocephala and Atractylodes lancea.

Uses

Atractylone (Atractylon) is a sesquiterpenoid extracted from Atractylodis Rhizoma. Atractylone (Atractylon) alleviates influenza A virus (IAV)-induced lung injury via regulating the TLR7 signaling pathway, and acts as a promising agent for IAV treatment. Atractylone (Atractylon) inhibits the degranulation of mast cell and exhibits potential for the treatment of mast cell-mediated allergic reactions[1][2].

Definition

ChEBI: Atractylone is a sesquiterpenoid.

Biological Activity

Atractylon is a main active component of Atractylodis Rhizoma th at exhibits antibacterial, antiviral, anti-inflammatory, anti-allergic, anticancer, gastroprotective and neuroprotective activities. Atractylon inhibits proliferation, induces apoptosis and blocks invasion in varies hepatic cancer cell lines. It inhibits the expression of Bcl-2 and promotes the expression of Bax.

target

IL Receptor | VEGFR | Histamine Receptor

References

[1] Cheng Y, et al. Antiviral activities of atractylon from Atractylodis Rhizoma. Mol Med Rep. 2016 Oct;14(4):3704-10. DOI:10.3892/mmr.2016.5713
[2] Han NR, et al. Inhibitory effects of atractylone on mast cell-mediated allergic reactions. Chem Biol Interact. 2016 Oct 25;258:59-68. DOI:10.1016/j.cbi.2016.08.015

ATRACTYLINE(DISCONTINUED)(SH) Preparation Products And Raw materials

Raw materials

Preparation Products

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ATRACTYLINE(DISCONTINUED)(SH) Suppliers

China 143 India 1 United Kingdom 2 United States 6 USA 1 Global 153

Shanghai Moqi Biological Technology Co., LTD

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View Lastest Price from ATRACTYLINE(DISCONTINUED)(SH) manufacturers

Shanghai Standard Technology Co., Ltd.

Product: Atractylon 6989-21-5
Price: US $0.00/mg
Min. Order: 20mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2020-04-26

Career Henan Chemical Co

Product: ATRACTYLINE(DISCONTINUED)(SH) 6989-21-5
Price: US $9.80/KG
Min. Order: 1KG
Purity: ≥98%
Supply Ability: 20 tons
Release date: 2020-01-09

6989-21-5, ATRACTYLINE(DISCONTINUED)(SH)Related Search:

Atractylodis Macrocephalae Rhizoma Curcumenol β-Caryophyllene Furanodienone Atractylodin Curzerenone Curcumol Artemether beta-Eudesmol HINESOL Curdione Curzerene (1S,3aβ,8aα)-1-Methyl-1α,4α-dihydroxy-4-(hydroxymethyl)-7β-[1-methyl-1-(β-D-glucopyranosyloxy)ethyl]decahydroazulene-2-one alpha-Cyperone Eupatorii Herba Achyranthis bidentatae radix Angelicae Dahuricae Radix CYPERI RHIZOMA

Atractyline

ATRACTYLINE(DISCONTINUED)(SH)

(4aS)-4,4aα,5,6,7,8,8a,9-Octahydro-3,8aβ-dimethyl-5-methylenenaphtho[2,3-b]furan

(4aS,8aR)-3,8a-diMethyl-5-Methylene-4,4a,5,6,7,8,8a,9-octahydronaphtho[2,3-b]furan

Naphtho[2,3-b]furan, 4,4a,5,6,7,8,8a,9-octahydro-3,8a-diMethyl-5-Methylene-, (4aS,8aR)-

(4aS,8aR)-4,4a,5,6,7,8,8a,9-Octahydro-3,8a-dimethyl-5-methylene-naphtho[2,3-b]furan

6989-21-5

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